University of California

Center for Animal Alternatives

Readings and Resources on
Monoclonal Antibodies

Altweb: Special Section on Monoclonal Antibodies - policies, regulations, guidelines, recommendations

Altweb: Special Section on Monoclonal Antibodies - reports and proceedings

AWIC: Guidelines and Policies

DePoyster, J.D. "Animal Care's position on Alternatives in Monoclonal Antibody Production, a workshop of The Johns Hopkins University Center for Alternatives to Animal Testing (CAAT) and The Office for Protection from Research Risks, National Institutes of Health, Baltimore MD, USA 1997 Sep 24-25.

European laboratory animal research legislation in France, Germany, The Netherlands, Switzerland, and United Kingdom. European Biomedical Research Association.

Hendriksen, C.F.M. "A call for a European prohibition of monoclonal antibody production by the ascites procedure in laboratory animals." Alternatives to Laboratory Animals: ATLA 26(4) 1998 Jul/Aug:523-536.

Hendriksen, C.; Rozing, J.; Van der Kamp, M.; et al. "The European perspective." Proceedings for 'Alternatives in Monoclonal Antibody Production', a workshop of The Johns Hopkins University Center for Alternatives to Animal Testing (CAAT) and The Office for Protection from Research Risks, National Institutes of Health, Baltimore MD, USA 1997 Sep 24-25.

Jackson, L.R.; Fox, J.G. "Institutional policies and guidelines on adjuvants and antibody production." Institute of Laboratory Animal Resources: ILAR Journal 37(3) 1995:141-152.

Address for reprints: Reprints, European Centre for the Validation of Alternative Methods (ECVAM), TP580, JRC Environment Institute, 21020, Ispra (VA), Italy

National Health and Meidcal Research Council (NHMRC): Guidelines on Monoclonal Antibody Production.

Sibal, L.R. "Regulatory issues regarding alternatives in monoclonal antibody production." Proceedings for 'Alternatives in Monoclonal Antibody Production', a workshop of The Johns Hopkins University Center for Alternatives to Animal Testing (CAAT) and The Office for Protection from Research Risks, National Institutes of Health, Baltimore MD, USA 1997 Sep 24-25.

Ward, P.A.; Adams, J.; Faustman, D.; et al. Monoclonal Antibody Production: A Report of the Committee on Methods of Producing Monoclonal Antibodies. Institute for Laboratory Animal Research (ILAR), National Research Council, National Academy Press, Washington, DC 1999.

"Guidelines for using the ascites method of monoclonal antibody production". Johns Hopkins Animal Care and Use 2001 September 20.

"IACUC/LARC standard procedures on antibody production". University of California, San Francisco.

"Recommendations for the production of ascitic fluid." University of Iowa, Animal Care Unit 1998 Feb 25.

"Recommendations for the production of hybridomas." University of Iowa, Animal Care Unit 1997 Jun 17.

"Recommendations for use and alternatives to Freund's Complete Adjuvant." University of Iowa, Animal Care Unit 1996 Nov 19.

"Monoclonal Antibody Production Guidelines". Institutional Animal Care and Use Committee, University of Tennessee.

Altweb News on Monoclonal Antibody

Lamborn, C. "Critics cry foul in MAb review." Lab Animal 28(1) 1999 Jan:10-11.

Lamborn, C. "NRC Report opposes ban on MAb ascites production." Lab Animal 28(5) 1999 May:10-11.

Matfield, M. "ECVAM report: monoclonal Ab production." European Biomedical Research Association: EBRA Bulletin 1997 Aug.

Mark Matfield (correspondence), European Biomedical Research Association, 58 Great Marlborough St, London W1V 1DD, UK, email secretariat@ebra.org

McArdle, J. "Antibodies without animals." PSYETA News 18 1998 Spring:6-7.

Schulhof, J.; Lamborn, C. "Jumping from the banned wagon." Lab Animal 27(2) 1998 Feb:9

"US campaign to end ascites methods." Fund for the Replacement of Animals in Medical Experiments: FRAME News 43 1997 Sep:8.

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