School Research Centers & Public Service Units School Clinical & Diagnostic Services Units SVM Office of Research Programs Internal Web Site for Faculty, Staff, and Students Search SVM web sites Continuing Education Opportunities for Veterinarians How to Support the School SVM Research & Service Units Veterinary Medical Teaching Hospital Information and Resources for Prospective Students Teaching Programs at the School of Veterinary Medicine Administrative and Organizational Information about the School Learn About New Developments at the School Return to the School of Veterinary Medicine Home Page
Center for Companion Animal Health
CCAH Supported Research Accomplishments

  Choose topic from drop-down list
up Anesthesia

Dexmedetomidine for balanced anesthesia in cats
Principle Investigators: Bruno Pypendop, Jan Ilkiw, Kristine Siao (2008-2009)

Evaluation of xenon for anesthesia in cats
Principle Investigators: Bruno Pypendop, Jan Ilkiw (2007-2008)

Pharmacokinetics and Anesthetic Effects of Fentanyl in Red-Tailed Hawks
Principle Investigators: Michelle Hawkins, Peter Pascoe, Theresa Baumgartner (2007-2008)

Comparison of the effect of isoflurane and propofol on urodynamics in cats
Principle Investigators: Jodi Westropp, Bruno Pypendop, Todd Cohen (2006-2007)

up Behavior

Support for the Companion Animal Behavior Program
Principle Investigator: Ben Hart (Multiyear)

Effects of catnip and feline facial pheromone on behavioral health of cats
Principle Investigators: Leslie Lyons, Eranda Rajapaksha (2007-2008)

Exploration of the use of antioxidants and mitochondrial cofactors to improve behavioral abnormalities of aging dog. (Matching Funds - AVMF Grant #CON-04-01).
Principle Investigators: Ben Hart, Laurie Bergman (2006-2007)

Effect of anti-anxiety medicines on urine spraying
Principle Investigator: Ben Hart (2001-2002)

up Cancer

Immunohistochemical profiling of feline oral squamous cell carcinoma and correlation with clinical data
Principle Investigators: Katherine Skorupski, Ellen Sparger (2007-2008)

The canine Immunoglobulin Kappa locus: A target for clonality assessment in B cell lymphoma
Principle Investigator: Peter F. Moore (2007-2008)

Deciphering the inheritance pattern and genetics of feline lymphosarcoma
Principle Investigator: Leslie A. Lyons (2006-2007)

Chromosome aberrations and Bcl-2 / P-glycoprotein expression in feline intestinal lymphoma
Principle Investigators: William Vernau, Peter Moore, Leslie Lyons, Lutz Froenicke (2006-2007)

Targeted imaging of canine lymphoma
Principle Investigator: Allison Zwingenberger, Michael S.Kent, Erik Wisner, Kit Lam (2006-2007)

Lymphoma - retro study of the results of chemotherapy
Principle Investigator: B.R. Madewell (1999)

Laser therapy (Photo dynamic Therapy) for cancer
Principle Investigators: B.R. Madewell, R. Higgins (1993-1998)

up Genetics

Mapping a canine dwarfism locus
Principle Investigator: Danika L. Bannasch (2007-2008)

Linkage disequilibrium mapping in feline progressive retinal atrophy
Principle Investigator: Leslie A. Lyons (2007-2008)

Genetic mapping of the feline craniofacial defect
Principle Investigator: Leslie A. Lyons (2007-2008)

DNA markers for genetic analysis of ferrets with cancer
Principle Investigators: Holly B. Ernest, Michelle Hawkins (2007-2008)

Correcting metabolic errors in the cat with adult stem cells
Principle Investigators: Phillip R. Vulliet, Quinton R. Rogers, Leslie A. Lyons (2006-2007)

Refinement of the candidate gene list for hyperuricosuria in the Dalmatian
Principle Investigator: Danika L. Bannasch (2005-2006)

1st Residency in Veterinary Genetics (worldwide)
Principle Investigators: N.C. Pedersen, D. Bannasch-Metallinos (1998)

International Feline Genetics Conference 2000
Principle Investigator: Leslie A. Lyons

up Infectious Disease

Oral shedding of Bartonella in cats: Correlation with bacteremia
Principle investigators: Bruno Chomel, Kate Hurley (2007-2008)

Campylobacter virulence genes: Detection and role in disease
Principle Investigator: Barbara A. Byrne, Stanley Marks, Nadira Chouicha (2007-2008)

Phase III Studies on the heritability of resistance/susceptibility to feline enteric coronavirus infection in randomly-bred, colony reared, domestic cats
Principle Investigators: Niels C. Pedersen, Leslie A. Lyons (2006-2007)

Pathogenicity of 'Candidatus Mycoplasma haemominutum' in cats
Principle Investigator: Jane Sykes (2006-2007)

Could Cat Scratch Disease pose a dangerous risk to cat owners who are immune-compromised (such as AIDs patients)?
Principle Investigator: Bruno Chomel

1st Shelter Medicine Program (worldwide).

Residency and training program; managing health, with a goal to increase adaptability and decrease euthanasia
Principle Investigator: J.E. Foley (2001)

Determining causes/risk factors for and the management of cats living in multi-cat facilities (esp. life threatening diseases such as FIP, FeCV)
Principle Investigators: NC Pedersen, J.E. Foley

2001 Gastrointestinal: helicobacter - association with G.I. disorders
Principle Investigator: S.L. Marks (1997)

Molecular cloning of Feline Immunodeficiency Virus (Feline AIDS). Principle Investigator: E.E. Sparger

up Medicine and Epidemiology

Cardiology: Analysis of platelet function in feline hypertrophic cardiomyopathy Principle Investigators: Karl Jandrey, Fern Tablin, Mark Kittleson (2007-2008)

Epidemiology: Discovered vaccination could cause a type of cancer (fibrosarcomas) in cats Principle Investigator: P. Kass

Study on Relinquishment - why do owners give up their pets or animals to shelters? Principle Investigator: P. Kass (1996)

Endocrinology: Effectiveness of diagnostics: CT, MRI in cats with insulin resistant and non insulin resistant diabetes mellitus
Principle Investigator: E. Feldman (1999)

Determining proper concentrations of drugs for treatment of diabetes mellitus
Principle Investigator: R.W. Nelson (2000)

Use of high fiber diet for treatment of diabetes
Principle Investigator: R.W. Nelson

1st hemodialysis for cats in kidney failure (worldwide)
Principle Investigator: L.D. Cowgill (1994)

up Nutrition

Plasma amino acid concentrations in cats consuming commercial diets
Principle Investigators: Andrea Fascetti, Phil Kass, Jennifer Larsen; and Resident Cailin Heinze (2007-2008)

Can the water content in canned foods promote weight loss in obese cats?
Principle Investigators: Jon Ramsey, Andrea Fascetti, Alfreda Wei (2007-2008)

Do domestic cats (Felis Catus) adapt protein oxidation rates to dietary protein intake?
Principle Investigators: Andrea Fascetti, Jon Ramsey, Alice Green (graduate student) (2005-2006)

Determining optimum levels in commercial diets: Taurine (Note – This team discovered that the absence/low levels of Taurine in commercial cat food caused a devastating but common heart disease in cats; once added, virtually eliminated the disease) Principle Investigators: Morris, Q.R. Rogers, SL Marks, R. Backus (1992-1999)

Identifying optimal requirements, metabolism and toxicity levels: Vitamins A, B, K, Choline and chloride for cats Principle Investigators: Morris, Q.R. Rogers, SL Marks, R. Backus (1992-1999)

Copper influences reproductive efficiency in queens
Principle Investigators: Morris, Q.R. Rogers, SL Marks, R. Backus (1999)

Nutritional requirements of growing kittens: Folate
Principle Investigators: Morris, Q.R. Rogers, SL Marks, R. Backus (1999)

Vitamin D & kidney effects
Principle Investigators: Morris, Q.R. Rogers, SL Marks, R. Backus (1999)

Obesity and rapid weight loss
Principle Investigators: Morris, Q.R. Rogers, SL Marks, R. Backus (1994)

Requirements of vitamin D & kidney effects
Principle Investigators: Morris, Q.R. Rogers, SL Marks, R. Backus (1995)

Discovered decreased zinc in pregnant queens results in cleft palate of the kittens Principle Investigators: Morris, Q.R. Rogers, SL Marks, R. Backus (2000)

up Reproduction

The role of ovarian hormones in endometrial hyperplasia in queens
Principle Investigators: Linda Munson, Anneke Moresco (2006-2007)

Linking pregnancy failure in cats with low taurine levels
Principle Investigator: B.L. Lasley (2000)

Origin of ovarian interstitial tissue and incidence of endometrial hyperplasia in domestic and feral cats Principle Investigator: B.L. Lasley (2000)

up Urology

Urodynamic evaluation of cats with feline idiopathic cystitis
Principle Investigators: Jodi Westropp, Christine Wu (2007-2008)

Investigation of the role of Oxalobacter formigenes in canine hyperoxaluria and calcium oxalate urolithiasis
Principle Investogators: Stanley Marks, Gerald Ling (2002-2003)

Described the ultra structure of urinary calculi in cats
Principle Investigator: G.V. Ling (1996)

UC Davis Center for Companion Animal Health, School of Veterinary Medicine, UC Davis, Tel 530.752.7295