Publications resulting from Comparative Transplant Laboratory research

Wooldridge JD, Gregory CR, Mathews KG, Aronson LR, Kyles AE. The prevalence of malignant neoplasia in feline renal-transplant recipients. Vet Surg. 2002 Jan-Feb;31(1):94-97.

Kyles AE, Gregory CR, Griffey SM, Galvez J, Ramsamooj R, Morris RE. Evaluation of the clinical and histologic features of renal allograft rejection in cats.Vet Surg. 2002 Jan-Feb;31(1):49-56.

Adin CA, Gregory CR, Kyles AE, Cowgill L. Diagnostic predictors of complications and survival after renal transplantation in cats.Vet Surg. 2001 Nov-Dec;30(6):515-21.

Gregory CR, Katznelson S, Griffey SM, Kyles AE, Berryman ER. Fluvastatin in combination with rad significantly reduces graft vascular disease in rat cardiac allografts. Transplantation. 2001 Sep 27;72(6):989-93.

Kyles AE, Gregory CR, Griffey SM, Bernsteen L, Jackson J, Morris RE. Leflunomide analog, MNA-715, plus cyclosporine reduces renal allograft rejection in mismatched dogs. Transplant Proc. 2001 Feb-Mar;33(1-2):368-9.

Gregory CR, Katznelson S, Griffey SM, Kyles AE, Berryman ER. Fluvastatin in combination with RAD significantly reduces transplant coronary vasculopathy in rat cardiac allografts. J Heart Lung Transplant. 2001 Feb;20(2):253.

Kyles AE, Gregory CR, Jackson J, Ilkiw JE, Pascoe PJ, Adin C, Samii VF, Herrgesell E.Evaluation of a portocaval venograft and ameroid ring for the occlusion of intrahepatic portocaval shunts in dogs.Vet Surg. 2001 Mar-Apr;30(2):161-9.

Kyles AE, Gregory CR, Craigmill AL. Comparison of the in vitro antiproliferative effects of five immunosuppressive drugs on lymphocytes in whole blood from cats. Am J Vet Res. 2000 Aug;61(8):906-9.

Bernsteen L, Gregory CR, Kyles AE, Wooldridge JD, Valverde CR. Renal transplantation in cats. Clin Tech Small Anim Pract. 2000 Feb;15(1):40-5.

Yeh LS, Gregory CR, Theriault BR, Hou SM, Lecouter RA. A functional model for whole limb transplantation in the rat. Plast Reconstr Surg. 2000 Apr;105(5):1704-11.

Kyles AE, Gregory CR, Wooldridge JD, Mathews KG, Aronson LR, Bernsteen L, Ilkiw JE. Management of hypertension controls postoperative neurologic disorders after renal transplantation in cats.Vet Surg. 1999 Nov-Dec;28(6):436-41.

Bernsteen L, Gregory CR, Pollard RE, Griffey SM, Menwrath V. Comparison of two surgical techniques for renal transplantation in cats.

Bernsteen L, Gregory CR, Aronson LR, Lirtzman RA, Brummer DG. Acute toxoplasmosis following renal transplantation in three cats and a dog. J Am Vet Med Assoc. 1999 Oct 15;215(8):1123-6.

Pollard R; Nyland TG; Bernsteen L; Gregory CR; Hornof WJ.Utrasonographic evaluation of renal autografts in normal cats.  Veterinary Radiology and Ultrasound, 1999 Jul-Aug, 40(4):380-5.

Wooldridge JD; Gregory CR.  Ionized and total serum magnesium concentrations in feline renal transplant recipients.  Veterinary Surgery, 1999 Jan-Feb, 28(1):31-7.

Gregory CR; Stewart A; Sturges B; DeManvelle T; Cannon A; Ortega T; Harb M; Morris RE.  Leflunomide effectively treats naturally occurring immune-mediated and inflammatory diseases of dogs that are unresponsive to conventional therapy. Transplantation Proceedings, 1998 Dec, 30(8):4143-8.

Lui LT; Lai YC; Yeh LS; Hou SM; Jeng CR; Gregory CR.  Irradiation or temporal variations in immunosuppressive schedules do not  prevent graft-versus-host disease following rat limb allotransplantation.  Transplantation Proceedings, 1998 Dec, 30(8):3960-1.

Gregory CR; Silva HT; Patz JD; Morris RE.  Comparative effects of malononitriloamide analogs of leflunomide on whole  blood lymphocyte stimulation in humans, rhesus macaques, cats, dogs, and rats.  Transplantation Proceedings, 1998 Jun, 30(4):1047-8.

Gregory CR; Galili U; Hancock WW; Valverde CR; Griffey SM; Berryman ER; Morris RE.  Squirrel monkeys hyperacutely reject porcine musculocutaneous flaps despite a lack of naturally occurring xenoantibodies.  Transplantation Proceedings, 1998 Jun, 30(4):1082-3.

Gregory CR.  Immunosuppressive approaches to the prevention of graft vascular disease.  Transplantation Proceedings, 1998 May, 30(3):878-80.

Mathews KG; Gregory CR.  Renal transplants in cats: 66 cases (1987-1996).  Journal of the American Veterinary Medical Association, 1997 Dec 1,  211(11):1432-6.

Yeh LS; Gregory CR; Griffey SM; Lecouter RA; Hou SM; Morris RE.  Combination leflunomide and cyclosporine prevents rejection of functional  whole limb allografts in the rat.  Transplantation, 1997 Sep 27, 64(6):919-22.

Gregory CR; Mathews KG; Aronson LR; Ilkiw JE; LeCouteur RA; Aldrich J.  Central nervous system disorders after renal transplantation in cats.  Veterinary Surgery, 1997 Sep-Oct, 26(5):386-92.

Davidson EB; Gregory CR; Kass PH.  Surgical excision of soft tissue fibrosarcomas in cats.  Veterinary Surgery, 1997 Jul-Aug, 26(4):265-9.

Aronson LR; Gacad RC; Kaminsky-Russ K; Gregory CR; Mullen KD.  Endogenous benzodiazepine activity in the peripheral and portal blood of  dogs with congenital portosystemic shunts.  Veterinary Surgery, 1997 May-Jun, 26(3):189-94.

Nyland TG; Fisher PE; Gregory CR; Wisner ER.  Ultrasonographic evaluation of renal size in dogs with acute allograft  rejection.  Veterinary Radiology and Ultrasound, 1997 Jan-Feb, 38(1):55-61.

Yeh LS; Gregory CR; Griffey SM; Lecouteur RA; Morris RE.  Effects of leflunomide and cyclosporine on myocutaneous allograft  survival in the rat. Transplantation, 1996 Sep 27, 62(6):861-3.

Galili U; Gregory CR; Morris RE.  New World monkeys as a primate model for xenografts in the absence of anti-Gal.  Transplantation Proceedings, 1996 Apr, 28(2):567-8.

Lirtzman RA; Gregory CR; Levitski RE; Griffey SM; Yeh LS; Patz JD; Morris  RE.  Combined immunosuppression with leflunomide and cyclosporine prevents  MLR-mismatched renal allograft rejection in a mongrel canine model.  Transplantation Proceedings, 1996 Apr, 28(2):945-.

Gregory CR; Cooke JP; Patz JD; Berryman ER; Shorthouse R; Morris RE. Enhanced nitric oxide production induced by the administration of  L-arginine does not inhibit arterial neointimal formation after overwhelming alloimmune injury.  Journal of Heart and Lung Transplantation, 1996 Jan, 15(1 Pt 1):58-66.

Gregory CR; Lirtzman RA; Kochin EJ; Rooks RL; Kobayashi DL; Seshadri R;Scott D.  A mucosal apposition technique for ureteroneocystostomy after renal transplantation in cats.  Veterinary Surgery, 1996 Jan-Feb, 25(1):13-7.

Walls CM; Gregory CR; Beck LS; Cooke JP; Griffey SM; Kass PH.  Effects of growth factors and L-arginine on ischemic skin flaps in rats.  Veterinary Surgery, 1995 Nov-Dec, 24(6):484-91.

 Lirtzman RA; Gregory CR.  Long-term renal and hematologic effects of uninephrectomy in healthy  feline kidney donors.  Journal of the American Veterinary Medical Association, 1995 Oct 15,

Galili U; Gregory CR; Morris RE.  Contribution of anti-Gal to primate and human IgG binding to porcine  endothelial cells.  Transplantation, 1995 Jul 27, 60(2):210-3.

Morris RE; Huang X; Gregory CR; Billingham ME; Rowan R; Shorthouse R; BerryGJ.  Studies in experimental models of chronic rejection: use of rapamycin  (sirolimus) and isoxazole derivatives (leflunomide and its analogue) for  the suppression of graft vascular disease and obliterative bronchiolitis.  Transplantation Proceedings, 1995 Jun, 27(3):2068-9.

Gregory CR; Huang X; Pratt RE; Dzau VJ; Shorthouse R; Billingham ME; Morris RE. Treatment with rapamycin and mycophenolic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial  replacement.  Transplantation, 1995 Mar 15, 59(5):655-61.

Morris RE; Cao W; Huang X; Gregory CR; Billingham ME; Rowan R; ShorthouseRA.  Rapamycin (Sirolimus) inhibits vascular smooth muscle DNA synthesis in  vitro and suppresses narrowing in arterial allografts and in balloon-injured carotid arteries: evidence that rapamycin antagonizes growth factor action on immune and nonimmune cells.  Transplantation Proceedings, 1995 Feb, 27(1):430-1.

Massat BJ; Gregory CR; Ling GV; Cardinet GH; Lewis EL.  Cystourethropexy to correct refractory urinary incontinence due to  urethral sphincter mechanism incompetence. Preliminary results in ten  bitches.  Veterinary Surgery, 1993 Jul-Aug, 22(4):260-8.

Gregory CR; Huie P; Billingham ME; Morris RE.  Rapamycin inhibits arterial intimal thickening caused by both alloimmune  and mechanical injury. Its effect on cellular, growth factor, and cytokine  response in injured vessels.  Transplantation, 1993 Jun, 55(6):1409-18.

Gregory CR; Olander HJ; Kochin EJ; Gourley IM; Cousyn D; Levy J.  Oxalate nephrosis and renal sclerosis after renal transplantation in a  cat.  Veterinary Surgery, 1993 May-Jun, 22(3):221-4.

Gregory CR; Huie P; Shorthouse R; Wang J; Rowan R; Billingham ME; Morris RE.  Treatment with rapamycin blocks arterial intimal thickening following  mechanical and alloimmune injury.  Transplantation Proceedings, 1993 Feb, 25(1 Pt 1):120-1.

Gregory CR; Pratt RE; Huie P; Shorthouse R; Dzau VJ; Billingham ME; MorrisRE.  Effects of treatment with cyclosporine, FK 506, rapamycin, mycophenolic  acid, or deoxyspergualin on vascular muscle proliferation in vitro and in vivo.  Transplantation Proceedings, 1993 Feb, 25(1 Pt 1):770-1.

Kochin EJ; Gregory CR; Wisner E; Cain G; Gourley IM.  Evaluation of a method of ureteroneocystostomy in cats.  Journal of the American Veterinary Medical Association, 1993 Jan 15,  202(2):257-60.

Gregory CR.  Status of renal transplantation in the 1990s.  Seminars in Veterinary Medicine and Surgery (Small Animal), 1992 Aug,  7(3):183-6.

Gregory CR; Gourley IM; Kochin EJ; Broaddus TW.  Renal transplantation for treatment of end-stage renal failure in cats.  Journal of the American Veterinary Medical Association, 1992 Jul 15,  201(2):285-91.

Griffin DW; Gregory CR.  Prevalence of bacterial urinary tract infection after perineal  urethrostomy in cats.  Journal of the American Veterinary Medical Association, 1992 Mar 1,  200(5):681-4.

Gregory CR; Gourley IM; Snyder JR; Ilkiw J.  Definition of the gracilis musculocutaneous flap for distant transfer in cats.  American Journal of Veterinary Research, 1992 Jan, 53(1):153-6.

Gregory CR; Madewell BR; Griffey SM; Torten M.  Feline leukemia virus-associated lymphosarcoma following renal  transplantation in a cat.  Transplantation, 1991 Dec, 52(6):1097-9.

Vasseur PB; Stevenson S; Gregory CR; Rodrigo JJ; Pauli S; Heitter D;  Sharkey N.  Anterior cruciate ligament allograft transplantation in dogs.  Clinical Orthopaedics and Related Research, 1991 Aug(269):295-304.

Gregory CR; Gourley IM; Ferreira H; Moore PF; Imondi KA; Patz JD; Gregory  TA; Pedersen NC.  Pathologic studies of acute rejection of mismatched feline  musculocutaneous flaps. Effect of cyclosporine and prednisolone.  Transplantation, 1991 Jun, 51(6):1170-5.

Peterson SL; Gregory CR; Snyder JR; Whiting PG; Strack D; Breznock EM.  Splanchnic surface oximetry during experimental portal hypertension and  surgical manipulation of portosystemic shunts in dogs.  Veterinary Surgery, 1991 May-Jun, 20(3):164-8.

Gregory CR; Gourley IM; Cain GR; Patz JD; Imondi KA; Martin JA.  Mizoribine serum levels associated with enterotoxicity in the dog.  Transplantation, 1991 Apr, 51(4):877-81.

Gregory CR; Gourley IM.  Identification of muscle flaps in small animals.  Microsurgery, 1991, 12(2):136-9.

Ilkiw JE; Forsyth SF; Hill T; Gregory CR.  Atracurium administration, as an infusion, to induce neuromuscular  blockade in clinically normal and temporarily immune-suppressed cats.  Journal of the American Veterinary Medical Association, 1990 Nov 1,

Gregory CR; Gourley IM.  Use of flaps and/or grafts for repair of skin defects of the distal limb  of the dog and cat.  Problems in Veterinary Medicine, 1990 Sep, 2(3):424-32.

Gregory CR; Guilford WG; Berry CR; Olsen J; Pederson NC.  Enteric function in cats after subtotal colectomy for treatment of  megacolon.  Veterinary Surgery, 1990 May-Jun, 19(3):216-20.

Gregory CR; Gourley IM; Broaddus TW; Christy WC; Mayer CR.  Long-term survival of a cat receiving a renal allograft from an unrelated  donor.  Journal of Veterinary Internal Medicine, 1990 Jan-Feb, 4(1):1-3.

Griffin DW; Gregory CR; Kitchell RL.  Preservation of striated-muscle urethral sphincter function with use of a  surgical technique for perineal urethrostomy in cats. Journal of the American Veterinary Medical Association, 1989 Apr 15,  194(8):1057-60.

Gregory CR; Hietala SK; Pedersen NC; Gregory TA; Floyd-Hawkins KA; Patz JD.  Cyclosporine pharmacokinetics in cats following topical ocular  administration.  Transplantation, 1989 Mar, 47(3):516-9.

Gregory CR; Gourley IM; Bruyette DS; Schultz LJ.  Free jejunal segment for treatment of cervical esophageal stricture in a  dog.  Journal of the American Veterinary Medical Association, 1988 Jul 15,  193(2):230-2.

Gregory CR; Gourley IM; Koblik PD; Patz JD.  Experimental definition of latissimus dorsi, gracilis, and rectus  abdominus musculocutaneous flaps in the dog. American Journal of Veterinary Research, 1988 Jun, 49(6):878-84.

Gregory CR; Gourley IM; Cain GR; Broaddus TW; Cowgill LD; Willits NH; PatzJD; Ishizaki G.  Effects of combination cyclosporine/mizoribine immunosuppression on canine  renal allograft recipients.  Transplantation, 1988 May, 45(5):856-9.

Gregory CR; Gourley IM; Cain GR.  Effects of mizoribine and combination mizoribine/cyclosporine  immunosuppression on canine renal allograft recipients. Transplantation Proceedings, 1988 Apr, 20(2 Suppl 2):223-5.

Gregory CR; Gourley IM; Haskins SC; Cain GR; Ishizaki G; Cowgill LD; Willits  NH; Patz JD.  Effects of mizoribine on canine renal allograft recipients.  American Journal of Veterinary Research, 1988 Mar, 49(3):305-11.

Gregory CR; Gourley IM; Taylor NJ; Broaddus TW; Olds RB; Patz JD.  Preliminary results of clinical renal allograft transplantation in the dog  and cat.  Journal of Veterinary Internal Medicine, 1987 Apr-Jun, 1(2):53-60.

Gregory CR; Taylor NJ; Willits NH; Theilen GH.  Response to isoantigens and mitogens in the cat: effects of cyclosporin A.  American Journal of Veterinary Research, 1987 Jan, 48(1):126-30.

Gregory CR; Cullen JM; Pool R; Vasseur PB.  The canine sacroiliac joint. Preliminary study of anatomy,  histopathology, and biomechanics.  Spine, 1986 Dec, 11(10):1044-8.

Gregory CR; Willits NH.  Electromyographic and urethral pressure evaluations: assessment of  urethral function in female and ovariohysterectomized female cats.  American Journal of Veterinary Research, 1986 Jul, 47(7):1472-5.

Gregory CR; Holliday TA; Vasseur PB; Bruhl-Day RA; Parker HR; McNeal D.  Electromyographic and urethral pressure profilometry: assessment of  urethral function before and after perineal urethrostomy in cats.  American Journal of Veterinary Research, 1984 Oct, 45(10):2062-5.

Gregory CR.  Electromyographic and urethral pressure profilometry. Clinical application  in male cats.  Veterinary Clinics of North America. Small Animal Practice, 1984 May,  14(3):567-74.

Klein HW; Gourley IM.  Use of magnetic resonance spectroscopy in the evaluation of skin flap  circulation.  Annals of Plastic Surgery, 1988 Jun, 20(6):547-51.

Carlsen RC; Klein HW; Matthews CC; Gourley IM.  Recovery of free muscle grafts in rat: improvement is associated with an  increase in cyclic adenosine monophosphate concentration or use of the  condition/test paradigm.  Experimental Neurology, 1987 Dec, 98(3):616-32.

Watson J; Donald PJ; Gourley IM; Pool R; Tyler W.  Composite vascularized free-rib and pleural transfer for laryngotracheal  reconstruction.  Otolaryngology - Head and Neck Surgery, 1983 Aug, 91(4):384-95.

Edell DJ; Churchill JN; Gourley IM.  Biocompatibility of a silicon based peripheral nerve electrode.  Biomaterials, Medical Devices and Artificial Organs, 1982, 10(2):103-22.

Munger RJ; Gourley IM.  Cross lid flap for repair of large upper eyelid defects.  Journal of the American Veterinary Medical Association, 1981 Jan 1,  178(1):45-8.

Gourley IM; Viscido AJ; Richards LW; Pool RR.  Evaluation of expandable titanium endosseous implants in a dog.  Journal of Oral Implantology, 1981, 9(4):538-47.

Al-Sadi HI; Gourley IM.  Simplified method for studying mechanical properties of healing linear  skin wounds in the dog.  American Journal of Veterinary Research, 1977 Jun, 38(6):903-6.

Gourley IM; Richards LW; Cordy DR.  Titanium endosteal dental implants in the mandibles of beagle dogs: a 2  year study.  Journal of Prosthetic Dentistry, 1976 NOV, 36(5):550-66.