Center for Children's Environmental Health

Photo: Publications
Dr. Frank Sharp


Click on the article titles or PMIDs to see the full articles. If you cannot open an article, it means you do not have access rights to that journal. Please call 530-754-8157 to receive a hard copy of the article.

276 publications in the current project period.  J=Joint Publication, G=Grad Student, P=PostDoc, Jr=Junior Faculty, + = submitted for Just in Time, *=Cites NIEHS or EPA grant number for CCEH; N=no CCEH citation.  Graduate students were listed as co-authors on 87 CCEH papers during the current project period, junior faculty participated in writing 27 papers, and postdocs were listed on 32 papers.   

2012 Publications


* G - Ahn, K.C., T. Kasagami, H.-J. Tsai, N.H. Schebb, S.J. Gee and B.D. Hammock. An immunoassay to evaluate human/environmental exposure to the antimicrobial triclocarban. Env. Sci. Technol. 2012 46(1):374-81. PMID: 22077920. PMCID: PMC3258304.  Env

N - Bennett DH, Wu XM, Teague CH, Lee K, Cassady DL, Ritz B, Hertz-Picciotto I. Passive sampling methods to determine household and personal care product use. J Expo Sci Environ Epidemiol. 2012 Mar-Apr;22(2):148-60. Epub 2011 Dec 21. PMID:22189587. No PMCID. Epi 


N, P, Jr - Barrientos GC, Feng W, Truong K, Matthaei KI, Yang T, Allen PD, Lopez JR, Pessah IN. Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826I-RYR1 malignant hyperthermia-susceptible muscle.  J Biol Chem. 2012 Jan 20;287(4):2863-76. Epub 2011 Dec 2.  PMID: 22139840. PMCID: PMC3267780.  Neuro


+ J, G - Braunschweig D, Golub MS, Koenig CM, Qi L, Pessah IN, Van de Water J, Berman RF. Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model. J of Neuroimmunology. In Press. Immuno 


* J, G, Jr - Braunschweig D, Duncanson P, Boyce R, Hansen R, Ashwood P, Pessah IN, Hertz-Picciotto I, Van de Water J. Behavioral correlates of maternal antibody status among children with autism. J Autism Dev Disord 2012 Jul;42(7):1435-45. PMID: 22012245.  No PMCID. Immuno/behav


+ N, J - Cao Z, Hammock BD, McCoy M, Rogawski M, Lein P, Pessah I. Tetramethylenedisulfotetramine Alters Ca2+ Dynamics in Cultured Hippocampal Neurons: Mitigation by NMDA Blockade and GABAA Receptor Positive Modulation. Toxicol Sci. 2012 Aug 13. [Epub ahead of print] PMID: 22889812.  Neuro


+ * Cao Z, Hulsizer S, Tassone F, Tang HT, Hagerman RJ, Rogawski MA, Hagerman PJ, Pessah IN. Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Hum Mol Genet. 2012 Jul 1;21(13):2923-35. Epub 2012 Mar 30. PMID: 22466801.  PMCID:  PMC3373240.  Neuro


* J, G - Chaidez V, Hansen RL, Hertz-Picciotto I. Autism Spectrum Disorders in Hispanics and non-Hispanics. Autism. 2012 Mar 7. [Epub ahead of print] PMID: 22399446. No PMCID. Epi

+ * J, Jr, G, P - Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proc Natl Acad Sci U S A. 2012 Aug 13. [Epub ahead of print] PMID: 22891308. Neuro


N - Dutta SK, Mitra PS, Ghosh S, Zang S, Sonneborn D, Hertz-Picciotto I, Trnovec T, Palkovicova L, Sovcikova E, Ghimbovschi S, Hoffman EP. Differential gene expression and a functional analysis of PCB-exposed children: understanding disease and disorder development. Environ Int. 2012 Apr;40:143-54. Epub 2011 Sep 8. PMID: 21855147. PMCID: PMC3247643. Epi/gene/env 


N - Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD. Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. 


Proc Natl Acad Sci U S A. 2012 May 15;109(20):7923-8. Epub 2012 Apr 30. PMID: 22547813. PMCID: PMC3356662. Neuro


N - Ghosh R, Joad J, Benes I, Dostal M, Sram RJ, Hertz-Picciotto I. Ambient nitrogen oxides exposure and early childhood respiratory illnesses. Environ Int. 2012 Feb;39(1):96-102. Epub 2011 Nov 11. PMID:22208747. No PMCID.  Epi/env

* J, G - Heuer LS, Rose M, Ashwood P, Van de Water J.  2012.  Decreased levels of total immunoglobulin in children with autism are not a result of B cell dysfunction.  Journal of Neuroimmunology July 30 2012.  PMID:  22854260.  Immuno 


* G - Hua S, Nwosu CC, Strum JS, Seipert RR, An HJ, Zivkovic AM, German JB, Lebrilla CB. Site-specific protein glycosylation analysis with glycan isomer differentiation.  Anal Bioanal Chem. 2012 May;403(5):1291-302. Epub 2011 Jun 8.  PMID: 21647803.  No PMCID. Env



N - Hunsaker MR, Arque G, Berman RF, Willemsen R, Hukema RK. Mouse models of the fragile x premutation and the fragile X associated tremor/ataxia syndrome.  Results Probl Cell Differ. 2012;54:255-69.  PMID: 22009357.  No PMCID. Neuro 


N, G - Jusko TA, Sonneborn D, Palkovicova L, Kocan A, Drobna B, Trnovec T, Hertz-Picciotto I. Environ Health Perspect. Pre- and postnatal polychlorinated biphenyl concentrations and longitudinal measures of thymus volume in infants. 2012 Apr;120(4):595-600. Epub 2012 Jan 3. PMID: 22275729. PMCID: PMC3339462.  Epi/env

* Kim, H.J., M. McCoy, Z. Majkova, J. Dechant, S.J. Gee, S. Tabares-da Rosa, G.G. Gonzalez-Sapienza and B.D. Hammock. 2012. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Anal Chem. 84:1165-71. PMID: 22148739. PMCID: PMC3264785.   Env


* J, G - Koenig, C.M., Walker, C., Qi, L., Pessah, I.N. & Berman, R.F.  Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J Mice. Plos One 2012; 7(6):e38911. PMID: 22719983. PMCID: PMC3374803. Neuro/epi/env 


* J, G - Krakowiak, P., Cheryl K. Walker, Andrew A. Bremer, Alice S. Baker, Sally Ozonoff, Robin L. Hansen, Irva Hertz-Picciotto. Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders. Pediatrics 2012 May;129(5):e1121-8. PMID: 22492772. PMCID: PMC3340592.  Epi/behav

N - Liu J, Koscielska KA, Cao Z, Hulsizer S, Grace N, Mitchell G, Nacey C, Githinji J, McGee J, Garcia-Arocena D, Hagerman RJ, Nolta J, Pessah IN, Hagerman PJ. Signaling defects in iPSC-derived fragile X premutation neurons.  Hum Mol Genet. 2012 Sep 1;21(17):3795-805. Epub 2012 May 28. PMID: 22641815.  No PMCID. Neuro


Jr - Lyall K, Schmidt RJ, Hertz-Picciotto I (In Press). “The environment in autism spectrum disorders” In: PR Hof and JD Buxbaum (Eds.) The Neuroscience of Autism Spectrum Disorders. Elsevier.  Epi/env


* McCanlies EC, Fekedulegn D, Mnatsakanova A, Burchfiel CM, Sanderson WT, Charles LE, Hertz-Picciotto I. Parental Occupational Exposures and Autism Spectrum Disorder.  J Autism Dev Disord. 2012 Mar 8. [Epub ahead of print] PMID: 22399411. No PMCID. Epi/Env

+ Medici V, Shibata NM, Kharbanda KK, LaSalle JM, Woods R, Liu S, Engelberg JA, Devaraj S, Torok NJ, Jiang JX, Havel PJ, Lonnerdal B, Kim K, Halsted CH.  Wilson disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease.  Hepatology, in press.  Genetics 


* J, Jr - Mitchell MM, Woods R, Chi L-H, Schmidt RJ, Pessah IN, Kostyniak PJ, LaSalle JM (In Press). Levels of select PCB and PBDE congeners in human post-mortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder.  Environ. Mol. Mutagenesis.  


N - Mitra PS, Ghosh S, Zang S, Sonneborn D, Hertz-Picciotto I, Trnovec T, Palkovicova L, Sovcikova E, Ghimbovschi S, Hoffman EP, Dutta SK. Analysis of the toxicogenomic effects of exposure to persistent organic pollutants (POPs) in Slovakian girls: correlations between gene expression and disease risk.  Environ Int. 2012 Feb;39(1):188-99. Epub 2011 Dec 8. PMID: 22208759.  PMCID: PMC3259908.  Epi/Env/Gene 


N, G - Onore C, Careaga M, Ashwood P. The role of immune dysfunction in the pathophysiology of autism. Brain Behav Immun. 2012 26(3):383-92. PMID: 21906670.  No PMCID. Immuno

N - Onore C, Nordahl C, Young G, Van de Water J, Rogers S, P Ashwood P. Levels of Soluble Adhesion Molecules PECAM-1 and P-Selectin are decreased in Children with Autism Spectrum Disorder. Biological Psychiatry 2012 Jun 19 [Epub ahead of print]. PMID: 22717029.  No PMCID. Immuno 


N - Schebb, N.H., K.C. Ahn, H. Dong, S.J. Gee and B.D. Hammock. 2012. Whole blood is the sample matrix of choice for bio-monitoring of human triclocarban exposure. Chemosphere. 87:825-27.  PMID: 22273184.  No PMCID.  Env


N - Schebb, N.H., B. Franze, R. Maul, A. Ranganathan and B.D. Hammock. In vitro glucuronidation of the antibacterial triclocarban and its oxidative metabolites. Drug Metab Dispos 2012 40(1):25-31. PMID: 21953915.  PMCID: PMC3250046.  Env

N, J, Jr - Schmidt RJ, Tancredi DJ, Ozonoff S, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tassone F, Hertz-Picciotto I. Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. Am J Clin Nutr. 2012 Jul;96(1):80-9. PMID: 22648721.  PMCID: PMC3374734. Epi/Env/behav


* J, G - Shelton JF, Hertz-Picciotto I, Pessah IN. Tipping the Balance of Autism Risk: Potential Mechanisms Linking Pesticides and Autism.  Environ Health Perspect. 2012 Apr 11. [Epub ahead of print]  PMID: 22534084. No PMCID. Epi/Env


+ N - Stafstrom CE, Hagerman PJ, Pessah IN. Pathophysiology of Epilepsy in Autism Spectrum Disorders. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. PMID: 22787637 [PubMed] Books & Documents. Neuro


* + J - Tassone F, Choudhary NS, Tassone F, Durbin-Johnson B, Hansen R, Hertz-Picciotto I, Pessah I. Identification of Expanded Alleles of the FMR1 Gene in the CHildhood Autism Risks from Genes and Environment (CHARGE) Study. J Autism Dev Disord. 2012 Jul 6. [Epub ahead of print] PMID: 22767137.  Genetics


* P - Wayman GA, Bose DD, Yang D, Lesiak A, Bruun D, Impey S, Ledoux V, Pessah IN, Lein PJ. PCB 95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth. Environ Health Perspect. 120(7):1003-9.  PMID: 22534176.  PMCID: PMC3404671. Neuro


* P - Wayman GA, Yang D, Bose DD, Lesiak A, Ledoux V, Bruun D, Pessah IN, Lein PJ. PCB 95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. Environ Health Perspect. 120(7):997-1002. PMID: 22534141. PMCID:  PMC3404670. Neuro


* P - Woods R, Vallero RO, Golub MS, Suarez JK, Ta TA, Yasui DH, Chi LH, Kostyniak PJ, Pessah IN, Berman RF, Lasalle JM. Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation. Hum Mol Genet. 2012 Jun 1;21(11):2399-411. PMID: 22343140.  PMCID: PMC3349420.  Gene/Env

N - Wu XM, Bennett DH, Lee K, Cassady DL, Ritz B, Hertz-Picciotto I. Feasibility of using web surveys to collect time-activity data. J Expo Sci Environ Epidemiol. 2012 Mar-Apr;22(2):116-25. PMID: 21792233. No PMCID. Epi

N, Jr - Yuen B, Boncompagni S, Feng W, Yang T, Lopez JR, Matthaei KI, Goth SR, Protasi F, Franzini-Armstrong C, Allen PD, Pessah IN. Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage.  FASEB J. 2012 Mar;26(3):1311-22. Epub 2011 Nov 30.  PMID: 22131268.  PMCID: PMC3289506. Neuro/gene


J, G - Zerbo O, Iosif AM, Walker C, Ozonoff S, Hansen RL, Hertz-Picciotto I.  Is Maternal Influenza or Fever During Pregnancy Associated with Autism or Developmental Delays? Results from the CHARGE (CHildhood Autism Risks from Genetics and Environment) Study.  J Autism Dev Disord. 2012 May 5. [Epub ahead of print] PMID: 22562209.  No PMCID.  Epi/Immuno/Env/Behav


2011 Publications


* Ahn, K.C., S.J. Gee, H.J. Kim, P. Aronov, H. Vega, R.I. Krieger, B.D. Hammock. Immunochemical analysis of 3-phenoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides. Anal. Bioanal. Chem. 2011 401(4):1285-93. PMID 21717113.  No PMCID.  Env

* Ahn, K.C., HJ. Kim, M.R. McCoy, S.J. Gee and B.D. Hammock. 2011.  Immunoassays and biosensors for monitoring environmental and human exposure to pyrethroid insecticides. J. Agric. Food Chem. 59(7):2792-2802. PMID:  21105656.  PMCID: PMC3070843.  Env


* G - Ahn, K.C., H-J. Tsai, C. Morisseau, H. Huang, A. Samra, D.P.Y. Chang, S.J. Gee and B.D. Hammock.  In vitro biological activities of the antimicrobials triclocarban, its analogs and triclosan: enzyme-based bioassay and relevance to exposure monitoring.  Toxicological Sci. In Press.  Env


* J, Jr, G - Angkustsiri K, Krakowiak P, Moghaddam B, Wardinsky T, Gardner J, Kalamkarian N, Hertz-Picciotto I, Hansen RL. Minor physical anomalies in children with autism spectrum disorders. Autism 2011 Nov;15(6):746-60.  PMID: 21610186. No PMCID.  Epi/gene


N - Ashwood P, Corbett BA, Kantor A, Schulman H, Van de Water J, Amaral DG.  In search of cellular immunophenotypes in the blood of children with autism. PLoS One 2011 6(5):e19299. PMID: 21573236.  PMCID: PMC3087757.  Immuno


* J, G - Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Altered T cell responses in children with autism. Brain Behav Immun. 2011 Jul;25(5):840-9. Epub 2010 Sep 15. PMID: 20833247. PMCID: PMC3039713.  Immuno/Neuro


* J, G - Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J.
Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders.
J Neuroimmunol. 2011 Mar;232(1-2):196-9. PMID: 21095018. PMCID: PMC3053074.



G - Berman, R.F., Koenig, C., Hunsaker, M.R., Pessah, I.N. & LaSalle, J.M.
Neuro-developmental Toxicology and Autism Spectrum Disorders, W. Slikker & C. Wang, (ed), Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies and Mechanisms, Vol. 1, John Wiley & Sons, London. March 2011.  Neuro


N - Berman RF, Murray KD, Arque G, Hunsaker MR, Wenzel HJ. Abnormal dendrite and spine morphology in primary visual cortex in the CGG knock-in mouse model of the fragile X premutation.  Epilepsia. 2012 Jun;53 Suppl 1:150-60. PMID: 22612820. No PMCID. Neuro/Gene


N - Bookman EB, McAllister K, Gillanders E, Wanke K, Balshaw D, Rutter J, Reedy J, Shaughnessy D, Agurs-Collins T, Paltoo D, Atienza A, Bierut L, Kraft P, Fallin MD, Perera F, Turkheimer E, Boardman J, Marazita ML, Rappaport SM, Boerwinkle E, Suomi SJ, Caporaso NE, Hertz-Picciotto I, Jacobson KC, Lowe WL, Goldman LR, Duggal P, Gunnar MR, Manolio TA, Green ED, Olster DH, Birnbaum LS; for the NIH G × E Interplay Workshop participants. Gene-environment interplay in common complex diseases: forging an integrative model-recommendations from an NIH workshop.  Genet Epidemiol. 2011 Feb 9. [Epub ahead of print] PMID:21308768.  Gene/Env

N - Borthwell RM, Hunsaker MR, Willemsen R, Berman RF. Spatiotemporal processing deficits in female CGG KI mice modeling the fragile X premutation.  Behav Brain Res. 2012 Apr 26;233(1):29-34. [Epub ahead of print]  PMID: 22561129. PMCID: PMC3378809. Neuro 


N, P - Bose D. D. and Pessah, I. N. (2011). Ryanodine receptor type 1. UCSD Nature Molecule Pages.  Published online 24 Feb 2011. molecule/query?afcsid=A002108.  No PMID.  No PMCID.  Neuro

* Chichlowski M, German JB, Lebrilla CB, Mills DA. The influence of milk oligosaccharides on microbiota of infants: opportunities for formulas.  Annu Rev Food Sci Technol. 2011;2:331-51. Review. PMID: 22129386. No PMCID.  Env 

N - Cunningham CL, Martínez Cerdeño V, Navarro Porras E, Prakash AN, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC. Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development. Hum Mol Genet. 2011 Jan 1;20(1):64-79. Epub 2010 Oct 8.  PMID: 20935171.  PMCID: PMC3000676.  Neuro/gene/develop


* G - Dallas DC, Martin WF, Strum JS, Zivkovic AM, Smilowitz JT, Underwood MA, Affolter M, Lebrilla CB, German JB. N-linked glycan profiling of mature human milk by high-performance microfluidic chip liquid chromatography time-of-flight tandem mass spectrometry.  J Agric Food Chem. 2011 Apr 27;59(8):4255-63. Epub 2011 Mar 18.  PMID: 21384928. No PMCID. Env


N - Diep AA, Hunsaker MR, Kwock R, Kim K, Willemsen R, Berman RF. Female CGG knock-in mice modeling the fragile X premutation are impaired on a skilled forelimb reaching task. 


Neurobiol Learn Mem. 2012 Feb;97(2):229-34. Epub 2011 Dec 21. PMID: 22202169. PMCID: PMC3278548. Neuro/gene/behav


N - Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR.  (2011). Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak.  Proc. Natl. Acad. Sci. U S A,  108: 7046-51. PMID: 21482776. PMCID: PMC3084091.  Neuro


* P, Jr - Feng W, Barrientos GC, Cherednichenko G, Yang T, Padilla IT, Truong K, Allen PD, Lopez JR, Pessah IN. Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice. Mol Pharmacol. 2011 Mar;79(3):420-31. Epub 2010 Dec 14.  PMID: 21156754. PMCID: PMC3061367.  Neuro 


* German JB. Dietary lipids from an evolutionary perspective: sources, structures and functions. 


Matern Child Nutr. 2011 Apr;7 Suppl 2:2-16. Review.  PMID: 21366863. No PMCID. Env/gene


* G - German JB, Zivkovic AM, Dallas DC, Smilowitz JT. Nutrigenomics and personalized diets: What will they mean for food?  Annu Rev Food Sci Technol. 2011;2:97-123. Review. 


PMID: 22129377.  No PMCID. Env/gene/translation


N - Ghosh R, Amirian E, Dostal M, Sram RJ, Hertz-Picciotto I. Indoor coal use and early childhood growth. Arch Pediatr Adolesc Med. 2011 Jun;165(6):492-7. Epub 2011 Feb 7. PMID:21300646.  No PMCID. Epi/env/develop

* J, P - Giulivi C, Ross-Inta C, Omanska-Klusek A, Napoli E, Sakaguchi D, Barrientos G, Allen PD, Pessah IN. Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice.  J Biol Chem. 2011 Jan 7;286(1):99-113. Epub 2010 Oct 26.  PMID: 20978128. PMCID: PMC3013050. Cites 012691 (wrong # published?) Special thank you to Peter Green in this article.  So it is really a joint publication.  Neuro


* J, P, G - Goines, PE, Croen, LA, Braunschweig, D, Yoshida, CK, Grether, J, Hansen, R, Kharrazi, M, Ashwood, P, and Van de Water, J.  Increased mid-gestational IFN-gamma, IL-4, and IL-5 in women giving birth to a child with autism: a case-control study. Molecular Autism, 2011 2:13.  PMID: 21810230.  PMCID: PMC3170586.  Immuno

* J, P, Jr, G - Goines PE, Haapanen LD, Boyce RB, Duncanson PM, Braunschweig D, Delwiche L, Hansen R, Hertz-Picciotto I, Ashwood P, Van de Water J (epub Dec 2010). Autoantibodies to cerebellum in children with autism associated with behavior. Brain Behav Immun 2011;25(3):514-23. PMID: 21134442.  PMCID:  PMC3039058.  Immuno/behav


N - Greco CM, Navarro CS, Hunsaker MR, Maezawa I, Shuler JF, Tassone F, Delany M, Au JW, Berman RF, Jin LW, Schumann C, Hagerman PJ, Hagerman RJ. Neuropathologic  features in the hippocampus and cerebellum of three older  men with fragile X syndrome. Mol Autism. 2011 Feb 8;2(1):2. PMID: 21303513.  PMCID: PMC3045897. Neuro


N - Hasenau, A-L., G. Nielsen, C. Morisseau, B.D. Hammock, H. Wulff and R. Köhler. 2011. Improvement of endothelium-dependent vasodilations by SKA-31 and SKA-20, activators of small- and intermediate conductance Ca(2+)-activated K(+)-channels. Acta Physiol. (Oxf). 203(1):117–126. PMID:  21362152.  PMCID:  PMC3139805.  Env/neuro

N, J - Herr CE, Ghosh R, Dostal M, Skokanova V, Ashwood P, Lipsett M, Joad JP, Pinkerton KE, Yap PS, Frost JD, Sram R, Hertz-Picciotto I.  Exposure to air pollution in critical prenatal time windows and IgE levels in newborns.  Pediatr Allergy Immunol 2011 22(1 Pt 1):75-84. PMID: 20609135.  No PMCID.  Epi/Env/Immuno


* J, G - Hertz-Picciotto I, Bergman A, Fangstrom B, Rose MB, Krakowiak P, Pessah IN, Hansen RL, Bennett DH. Polybrominated diphenyl ethers in relation to autism and developmental delay: A case-control study.  Environ Health. 2011 Jan 5;10(1):1. PMID: 21205326  PMCID: PMC3029221. Epi/env


* G - Heuer, L, Braunschweig, D, Ashwood, P, Van de Water, J, and Campbell, DB. Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression. Translational Psychiatry 1, e48, 2011. doi:10.1038/tp.2011.48 No PMID. No PMCID. Immuno/gene


N - Horváthová M, Jahnová E, Palkovičová L, Trnovec T, Hertz-Picciotto I. The kinetics of cell surface receptor expression in children perinatally exposed to polychlorinated biphenyls. J Immunotoxicol. 2011 Oct-Dec;8(4):367-80. PMID:22047017. No PMCID.  Immuno/env/epi


N - Horváthová M, Jahnová E, Palkovičová L, Trnovec T, Hertz-Picciotto I. Dynamics of lymphocyte subsets in children living in an area polluted by polychlorinated biphenyls. J Immunotoxicol. 2011 Oct-Dec;8(4):333-45. Epub 2011 Oct 20. PMID:22013978.  No PMCID. Immuno/env/epi


N - Hunsaker MR, Greco CM, Spath MA, Smits AP, Navarro CS, Tassone F, Kros JM, Severijnen LA, Berry-Kravis EM, Berman RF, Hagerman PJ, Willemsen R, Hagerman RJ, Hukema RK. Widespread non-central nervous system organ pathology in fragile X premutation carriers with fragile X-associated tremor/ataxia syndrome and CGG knock-in mice. 


Acta Neuropathol. 2011 Oct;122(4):467-79. PMID: 21785977. PMCID: PMC3222079. Neuro/gene


N - Hunsaker MR, Greco CM, Tassone F, Berman RF, Willemsen R, Hagerman RJ, Hagerman PJ. Rare intranuclear inclusions in the brains of 3 older adult males with fragile x syndrome: implications for the spectrum of fragile x-associated disorders.  J Neuropathol Exp Neurol. 2011 Jun;70(6):462-9. PMID: 21572337.  PMCID: PMC3109086. Neuro 


N - Hunsaker MR, von Leden RE, Ta BT, Goodrich-Hunsaker NJ, Arque G, Kim K, Willemsen R, Berman RF. Motor deficits on a ladder rung task in male and female adolescent and adult CGG knock-in mice.  Behav Brain Res. 2011 Sep 12;222(1):117-21. Epub 2011 Mar 31. 


PMID: 21440572.  PMCID: PMC3095688. Neuro/gene/behav


N, G - Jusko TA, De Roos AJ, Schwartz SM, Lawrence BP, Palkovicova L, Nemessanyi T, Drobna B, Fabisikova A, Kocan A, Jahnova E, Kavanagh TJ, Trnovec T, Hertz-Picciotto I. Maternal and early postnatal polychlorinated biphenyl exposure in relation to total serum immunoglobulin concentrations in 6-month-old infants. J Immunotoxicol. 2011 Jan-Mar;8(1):95-100. PMID:21299357. PMCID:PMC3086069.  Epi/env/immuno


* Kim HJ, McCoy M, Gee SJ, González-Sapienza GG, Hammock BD. Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules.  Anal Chem. 2011 Jan 1;83(1):246-53. Epub 2010 Dec 9.  PMID: 21141939. PMCID: PMC3031424. Env 


* G, P, Jr - Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN.
Para- and Ortho-Substitutions are Key Determinants of Polybrominated Diphenyl Ether Activity Toward Ryanodine Receptors and Neurotoxicity.
Environ Health Perspect. 2011. 119(4):519-26. PMID: 21106467. PMCID: PMC3080935.  Neuro/env


* G - Kim, K. H. and Pessah, I. N. (2011).  Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo. Neurotoxicology 32, 981-5.  PMID: 21571002. PMCID: PMC3181005.  Neuro/env/develop


N, G - Lein, P. J., Barnhart, C. D., Pessah, I. N. (2011). Acute hippocampal slice preparation and hippocampal slice cultures.  Methods Mol Biol 758:115-34. PMID: 21815062.  No PMCID. Neuro


* Li, N., J-Y. Liu, H. Qiu, T.R. Harris, P. Sirish, B.D. Hammock and N. Chiamvimonvat. 2011. Use of metabolomic profiling in the study of arachidonic acid metabolism in cardiovascular disease. Congest. Heart Fail. 17(1):42-46. PMID:  21272227.  No PMCID.  Env/gene


N, P - Lit L, Sharp FR, Bertoglio K, Stamova B, Ander BP, Sossong AD, Hendren RL.  Gene expression in blood is associated with risperidone response in children with autism spectrum disorders.  Pharmacogenomics J. 2011 Jun 7 [Epub ahead of print]. PMID:  21647175.  PMCID:  PMC3175502.  Gene/env


* Magby, J. P., Neal, A. P., Atchison, W. D., Pessah, I. N., Shafer, T. J. (2011). Channelopathies: Summary of the hot topic keynotes session/  Neurotoxicology, 32, 661-5.  PMID: 21756936. PMCID: PMC3200451.  Neuro


* Oberbauer AM, German JB, Murray JD. Growth hormone enhances arachidonic acid metabolites in a growth hormone transgenic mouse.  Lipids. 2011 Jun;46(6):495-504. Epub 2011 Mar 27.  PMID: 21442273. No PMCID. Env 


Pessah, I. N. (2011). Autism Spectrum Disorders. In: Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies and Mechanisms. (Edited by C Wang and W Slikker) John Wiley and Sons, Somerset, NJ.   Neuro/develop


N - Rossi, C. C., Van de Water, J., Rogers, S. J., Amaral, D. G. Detection of plasma autoantibodies to brain tissue in young children with and without autism spectrum disorders. Brain Behavior and Immunity 2011 25:1123-1135.  PMID: 21420487.  PMCID: PMC3313674.  Immuno/neuro


J, Jr - Schmidt RJ, Browne ML, Pessah IN (2011 Jan). Caffeine intake and risk of Neural Tube Defects. [Correspondence] Birth Defects Res A Clin Mol Teratol 91(1):68. Published Online, Dec 1, 2010.  Epi/env/neuro/develop


* J, Jr - Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tancredi DJ, Tassone F, Hertz-Picciotto I.  Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism.  Epidemiology 2011;22:476-485. PMID: 21610500. PMCID: PMC3116691.  Epi/env/gene


Stafstrom, C. E., Hagerman, P. J. and Pessah, I. N. (2011), Epilepsy in autism spectrum disorders. In Jasper's Basic Mechanisms of the Epilepsies, 4th Ed (Noebels, J. Avoli, M., Rogawski, M,. Olsen R., Delgado-Escueta, A., eds). Oxford University Press, 1160 pp.  Neuro


* J, P - Stamova B, Green PG, Tian Y, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Teng J, Gregg JP, Ashwood P, Van de Water J, Sharp FR. (2011)  Correlations between gene expression and mercury levels in blood of boys with and without autism. Neurotoxicity Res 19(1):31-48. [Epub 2009 Nov 24]. PMID: 19937285  PMCID: PMC3006666.  Gene/env


* J, G - Ta, T. A., Koenig, C. M., Golub, M. S., Pessah, I. N., Qi, L., Aronov, P. A., Berman, R. F.  (2011).  Bioaccumulation and behavioral effects of 2,2’,4,4’-tetrabromodiphenyl ether (BDE-47) in perinatally exposed mice.  Neurotoxicol  Teratol 33, 393-404.  PMID:  21334437.  No PMCID. Neuro/env/behav


* J - Tassone, F., Qi, L., Zhang, W., Hansen, R. L., Pessah, I. N.,  Hertz-Picciotto, I. (2011). MAOA, DΒH and SLC6A4 variants in CHARGE:  a case-control study of autism spectrum disorders.  Autism Res 4, 250-61  PMID: 21538940. PMCID: PMC3151322.  Gene/epi


* J, P - Tian Y, Green PG, Stamova B, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Gregg JP,  Ashwood P, Jickling G, Van de Water J, Sharp FR. (2011) Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls. Neurotoxicity Res 19(1):1-13. [Epub 2009 Nov 17]
PMID: 19921347. PMCID: PMC3006638.  Gene/env


N, G - Trnovec T, Dedík L, Jusko TA, Lancz K, Palkovičová L, Kočan A, Šovčíková E, Wimmerová S, Tihányi J, Patayová H,Hertz-Picciotto I. Assessment of exposure to PCB 153 from breast feeding and normal food intake in individual children using a system approach model. Chemosphere. 2011 Dec;85(11):1687-93. Epub 2011 Nov 1. PMID: 22051344. PMCID: PMC32288605. Epi/env


* Volk HE, Hertz-Picciotto I, Delwiche L, Lurmann F, McConnell R (epub Dec 2010). Residential proximity to freeways and autism in the CHARGE Study.  Environ Health Persp 2011 Jun; 119(6):873-7. PMID: 21156395.  PMCID: PMC3114825.  Epi/env


* J, G - Wills S, Rossi CC, Bennett J, Cerdeño VM, Ashwood P, Amaral DG, Van de Water J. Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism. Molecular Autism 2011 2:5. PMID: 21521495.  PMCID: PMC3108923. Immuno


N - Wu X, Apte M, Maddalena R, Bennett D. Volatile Organic Compounds in Small- and Medium- Sized Commercial Buildings in California. Environmental Science & Technology, 2011 Oct 15;45(20:9075-83. PMID: 21888354.  No PMCID. Epi 


N - Wu X, Bennett DH, Lee K, Cassady DL, Ritz B, Hertz-Picciotto I. Longitudinal variability of time-location/activity patterns of population at different ages: a longitudinal study in California. Environ Health. 2011 Sep 20;10:80. PMID:21933379. PMCID: PMC3184256. Epi 


 N - Wu XM, Bennett DH, Ritz B, Frost J, Cassady D, Lee K, Hertz-Picciotto I. 
Residential insecticide usage in northern California homes with young children.
J Expo Sci Environ Epidemiol. 2011 Jul-Aug;21(4):427-36.  PMID: 20588323  No PMC.  Epi/env


* Yakes EA, Arsenault JE, Islam MM, Ahmed T, German JB, Drake C, Hossain MB, Lewis BL, Rahman AS, Jamil KM, Brown KH. Dietary intake of polyunsaturated fatty acids among breast-feeding and non-breast-feeding 24- to 48-month-old children in Bangladesh.  J Pediatr Gastroenterol Nutr. 2011 Mar;52(3):351-9.  PMID: 21336160. PMCID: PmC3079426. Epi/env 


* G - Yakes EA, Arsenault JE, Munirul Islam M, Hossain MB, Ahmed T, Bruce German J, Gillies LA, Shafiqur Rahman A, Drake C, Jamil KM, Lewis BL, Brown KH. Intakes and breast-milk concentrations of essential fatty acids are low among Bangladeshi women with 24-48-month-old children.  Br J Nutr. 2011 Jun;105(11):1660-70. Epub 2011 Feb 16.  PMID: 21324215. No PMCID. Epi/env 


N - Yang, J., H. Dong and B.D. Hammock. 2011. Profiling the regulatory lipids: Another systemic way to unveil the biological mystery. Curr Opin Lipidol. 22(3):197-203. PMID: 21537174. Env


* G - Zerbo O, Iosif AM, Delwiche L, Walker C, Hertz-Picciotto I (2011).  Month of conception and risk of autism. Epidemiology 2011;22:469–475. PMID: 21543984.  No PMCID. Epi/env


* G, P - Zivkovic AM, Barile D. Bovine milk as a source of functional oligosaccharides for improving human health.  Adv Nutr. 2011 May;2(3):284-9. Epub 2011 Apr 30.  PMID: 22332060. PMCID: PMC3090169. Env 


* G - Zivkovic AM, German JB, Lebrilla CB, Mills DA. Human milk glycobiome and its impact on the infant gastrointestinal microbiota.  Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4653-8. Epub 2010 Aug 2.  PMID: 20679197. PMCID: PMC3063602. Env 


G - Zivkovic, A.M., N. Telis, J.B. German and B.D. Hammock. 2011.  Dietary omega-3 fatty acids in the modulation of inflammation and metabolic health.  No PMID. No PMCID. California Agr. 65(3):106-111.  Env


2010 Publications


N, Jr - Akins, R., Angkustsiri, K., Hansen, R., Complementary and Alternative Medicine in Autism: An Evidence-Based Approach to Negotiating Safe and Efficacious Interventions with Families, Neurotherapeutics 7(3): 307-319, 2010. PMID: 20643384. No PMCID.  Epi/env/neuro/clinical translation 


* J, G - Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J.
Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome.
Brain Behav Immun. 2010 Aug 10. [Epub ahead of print]
PMID: 20705131  PMCID:  PMC2991432.  Immuno/neuro/behav



* P - Barile D, Marotta M, Chu C, Mehra R, Grimm R, Lebrilla CB, German JB. Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry. J Dairy Sci. 2010 Sep;93(9):3940-9.  PMID: 20723667. No PMCID. Env/metab




N - Bannister RA, Estève E, Eltit JM, Pessah IN, Allen PD, López JR, Beam KG.  A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels.  J Gen Physiol. 2010 Jun;135(6):629-40. Epub 2010 May 17. 


PMID: 20479108. PMCID: PMC2888063.  Neuro/gene/epigene



Buie, T. Campbell, D.B., Fuchs, G.F., Furuta, G.T., Levy, J, Van de Water, J, Whitaker, A.H., Atkins, D. Bauman, M.L., Beaudet, A.L., Carr, E.G., Gershon, M.D., Hyman, S.L., Jirapinyo, P., Jyonouchi, H., Kooros, K, Kushak, R., Levitt, P., Levy, S.E., Lewis, J.D., Murray, K.F., Natowicz, M.R., Sabra, A., Wershil, B.K., Weston, S.C., Zeltzer, L., and H. Winter. Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report.
Pediatrics 125:supplement Jan 2010, S1-S18.  Immuno/env/clinical translation

N, G - Careaga M, Van de Water J, Ashwood P. Immune dysfunction in autism: a pathway to treatment.  Neurotherapeutics. 2010 7(3):283-92. Review. PMID: 20643381.  No PMCID.  Immuno/translation

* Chen Y, Tassone F, Berman RF, Hagerman PJ, Hagerman RJ, Willemsen R, Pessah IN. (2009)
Murine Hippocampal Neurons Expressing Fmr1 gene Premutations Show Early Developmental Deficits and Late Degeneration.
Hum Mol Genet. 2010 19(1):196-208. PMID:  19846466.  PMCID:  PMC2792156.  Neuro/gene/develop



N, Jr - Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF. Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+.  J Biol Chem. 2010 Dec 3;285(49):38453-62. Epub 2010 Oct 6.  PMID: 20926377. PMCID: PMC2992278.  Neuro 




N - Eltit JM, Yang T, Li H, Molinski TF, Pessah IN, Allen PD, Lopez JR.
RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes.
J Biol Chem. 2010 Apr 30;285(18):13781-7. Epub 2010 Mar 5.
PMID: 20207743. PMCID:  PMC2859541. Neuro

* Enstrom AM, Onore CE, Van de Water JA, and Ashwood P.
Differential monocyte responses to TLR ligands in children with autism spectrum disorders.
Brain Behav Immun 2010 Jan;24(1):64-71.
PMID:19666104. PMCID: PMC3014091.  Immuno

N - Estève E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, López JR.

A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR.  J Gen Physiol. 2010 Jun;135(6):619-28. Epub 2010 May 17.  PMID: 20479110. PMCID: PMC2888056.  Neuro/gene/env



N, Jr - Feng W, Cherednichenko G, Ward CW, Padilla IT, Cabrales E, Lopez JR, Eltit JM, Allen PD, Pessah IN.
Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1).
Biochem Pharmacol. 2010 May 13. [Epub ahead of print]
PMID: 20471964. PMCID:  PMC2907350.  Neuro/env

* Froehlich JW, Dodds ED, Barboza M, McJimpsey EL, Seipert RR, Francis J, An HJ, Freeman S, German JB, Lebrilla CB. Glycoprotein expression in human milk during lactation.  J Agric Food Chem. 2010 May 26;58(10):6440-8.  PMID: 20415418. PMCID: PMC2882031.  Env



* P - Goines, P. and Van de Water, J. A.
The immune system's role in the biology of autism.
Curr. Opin. Neurol. 2010 Apr;23(2):111-7. 
PMID:  20160651.  No PMC.  Immuno

* Giulivi C, Zhang YF, Omanska-Klusek A, Ross-Inta C, Wong S, Hertz-Picciotto I, Tassone F, Pessah IN.
Mitochondrial dysfunction in autism.
JAMA. 2010 Dec 1;304(21):2389-96.
PMID: 21119085. No PMCID. Gene

N - Golub MS.
Recent studies of iron deficiency during brain development in nonhuman primates.
Biofactors. 2010 Mar;36(2):111-6.
PMID: 20336711. No PMCID.  Neuro/env/develop

* Hall, L.M., M.G. Kimlin, P.A. Aronov, B.D. Hammock, J.R. Slusser, L.R. Woodhouse and C.B. Stephensen. 2010. 
Vitamin D intake needed to maintain target serum 25-hydroxyvitamin D concentrations in participants with low sun exposure and dark skin pigmentation is substantially higher than current recommendations.
J. Nutr. 140(3):542-550.
PMID: 20053937. PMCID: PMC2821886.  Env

N - Herr CE, Dostal M, Ghosh R, Ashwood P, Lipsett M, Pinkerton KE, Sram R, Hertz-Picciotto I.
Air pollution exposure during critical time periods in gestation and alterations in cord blood lymphocyte distribution: a cohort of livebirths.
Environ Health. 2010 Aug 2;9:46.
PMID: 20678227 PMC2927516. Epi/env/immuno/develop

N - Hertz-Picciotto I, Cassady D, Lee K, Bennett DH, Ritz B, Vogt R.
Study of Use of Products and Exposure-Related Behaviors (SUPERB): study design, methods, and demographic characteristics of cohorts.
Environ Health. 2010 Aug 29;9:54.
PMID: 20799988 PMC2940867. Epi

* J - Hertz-Picciotto I, Green PG, Delwiche L, Hansen R, Walker C, Pessah IN. (2010) 
Blood mercury concentrations in CHARGE Study children with and without autism.
Environ Health Persp 118(1):161-6. PMID: 20056569. PMC2831962. Online 22 October 2009.  Epi/env

N - Hertz-Picciotto, I, et. al. California Dental Association Foundation; American College of Obstetricians and Gynecologists, District IX.
Oral health during pregnancy and early childhood: evidence-based guidelines for health professionals.
J Calif Dent Assoc. 2010 Jun;38(6):391-403, 405-40.
No abstract available. PMID: 20645626. No PMC.  Epi/env/develop/translation

N - Hunsaker MR, Goodrich-Hunsaker NJ, Willemsen R, Berman RF. Temporal ordering deficits in female CGG KI mice heterozygous for the fragile X premutation.  Behav Brain Res. 2010 Dec 1;213(2):263-8. Epub 2010 May 15.  PMID: 20478339  PMCID: PMC2902565.  Neuro/gene



N, G - Jusko TA, De Roos AJ, Schwartz SM, Lawrence BP, Palkovicova L, Nemessanyi T, Drobna B, Fabisikova A, Kocan A, Sonneborn D, Jahnova E, Kavanagh TJ, Trnovec T, Hertz-Picciotto I. A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age.
Environ Res. 2010 May;110(4):388-95. Epub 2010 Apr 7. PMID: 20378105  PMCID: PMC2859670.  Epi/env/immuno



* Kim, H-J., M.A. Rossotti, K.C. Ahn, G.G. González-Sapienza, S.J. Gee, R. Musker and B.D. Hammock. 2010. Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47. Analytical Biochemistry 401:38-46. PMID:  20152791.  PMCID: PMC2861364.  Children's Center acknowledged, but not grant number.  Env

G - Lein, P.M., Kim, K.H., Berman, R.F. & Pessah, I.N.
Exposure of the developing brain to polychlorinated biphenyls influences the susceptibility of the adult brain to stress, W. Slikker, (ed), Developmental Neurotoxicology Research: Principles, Models, Techniques, Strategies and Mechanisms. 2010.  Neuro/env/develop

* G - Park HY, Hertz-Picciotto I, Sovcikova E, Kocan A, Drobna B, Trnovec T.Neuro-developmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study.
Environ Health. 2010 Aug 23;9:51.PMID: 20731829  PMCID: PMC2939589.  Epi/neuro/env/develop

* Paul R, Pessah IN, Gane L, Ono M, Hagerman PJ, Brunberg JA, Tassone F, Bourgeois JA, Adams PE, Nguyen DV, Hagerman R.
Early onset of neurological symptoms in fragile X premutation carriers exposed to neurotoxins.
Neurotoxicology. 2010 Aug;31(4):399-402. PMID: 20466021.  No PMCID. Neuro/env/gene

* Jr - Pessah IN, Cherednichenko G, Lein PJ.
Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity.
Pharmacol Ther. 2010 Feb;125(2):260-85. Epub 2009 Nov 25. Review. PMID: 19931307. PMCID: PMC2823855. Neuro/env

* Qi, Lihong, Ying-Fang Wang, Yulei He. (2010). A Comparison of Multiple Imputation and Fully Augmented Weighted Estimators for Cox regression with Missing Covariates. Statistics in Medicine. Nov; 29(25):2592-2604. PMID:  20806403. No PMCID. Epi

* Jr - Qiu H, Li N, Liu JY, Harris TR, Hammock BD, Chiamvimonvat N. Soluble Epoxide Hydrolase Inhibitors and Heart Failure.  Cardiovasc Ther. 2010 Apr 23. [Epub ahead of print].  PMID: 20433684. PMCID: PMC3325372. Env




* J, G - Rose M, Bennett DH, Bergman A, Fangstrom B, Pessah IN, Hertz-Picciotto I (2010).
PBDEs in 2-5 year-old children from California and associations with diet and indoor environment. Env Sci Technol 44(7):2648-53. PMID: 20196589.  No PMCID. Epi/env 

Jr - Schmidt RJ and LaSalle J (2010 Nov). “Interactions between folate, other B vitamins, DNA methylation, and neurodevelopmental disorders" In: N Maulik and G Maulik (Eds.) Nutrition, epigenetic mechanisms and human disease. CRC Press.  Epi/env/neuro/develop



N - Shahlaie K, Lyeth BG, Gurkoff GG, Muizelaar JP, Berman RF. Neuroprotective effects of selective N-type VGCC blockade on stretch-injury-induced calcium dynamics in cortical neurons.  J Neurotrauma. 2010 Jan;27(1):175-87.  PMID: 19772476. PMCID: PMC2824229.  Neuro



* G - Shelton J, Tancredi DJ, Hertz-Picciotto I (2010).
Independent and dependent contributions of advanced maternal and paternal ages for autism risk. Autism Res 3(1):30-39.
[Epub ahead of print] PMID: 20143326.  No PMCID. Erratum in Autism Res 3(2):98.  Epi

* G - Van Meter KC, Christiansen LE, Delwiche, LD, Azari R, Carpenter TE, Hertz-Picciotto I. (2010)
Geographic Distribution of Autism in California: A Retrospective Birth Cohort Analysis.
Autism Res 3(1):19-29. PMID: 20049980. No PMCID. Epi

N - Wenzel HJ, Hunsaker MR, Greco CM, Willemsen R, Berman RF. Ubiquitin-positive intranuclear inclusions in neuronal and glial cells in a mouse model of the fragile X premutation.  Brain Res. 2010 Mar 8;1318:155-66. Epub 2010 Jan 4.  PMID: 20051238. PMCID: PMC3086812.  Neuro



N - Wu XM, Bennett DH, Ritz B, Cassady DL, Lee K, Hertz-Picciotto I. Usage pattern of personal care products in California households. Food Chem Toxicol. 2010 Nov;48(11):3109-19. Epub 2010 Aug 7.PMID: 20696198  No PMC. Epi



* Zhang X, Lv CC, Tian J, Miao R.J., Xi W, Hertz-Picciotto I, Qi L. 2010. 
Prenatal and perinatal risk factors for autism in China. J Autism Dev Dis 40(11):1311-21. PMID: 20358271.  PMCID:  PMC2974190.  Epi/develop



2009 Publications


* G - Ahn, K.C., S.J. Gee, H-J. Tsai, D. Bennett, M.G. Nishioka, A. Blum, E. Fishman and B.D. Hammock. 2009. 
Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47.  Environ. Sci. Technol. 43(20):7784-7790. PMID: 19921894. No PMCID. Env

* J - Ashwood, P., Schauer, J., Pessah, I. N., and Van de Water, J. (2009)
Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders.
J. Neuroimmunology, 208(1-2):130-135, Epub 2009 Feb 10.
PMID 19211157.  PMCID: PMC2692510. Immuno/neuro/env

N - Bannister RA, Pessah IN, Beam KG. 
The skeletal L-type Ca(2+) current is a major contributor to excitation-coupled Ca(2+) entry.
J Gen Physiol. 2009 Jan;133(1):79-91.PMID: 19114636. PMCID: PMC2606935.  Neuro

N, P, Jr - Barrientos G, Bose DD, Feng W, Padilla I, Pessah IN. 
The Na+/Ca2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate (KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels. Mol Pharmacol. 2009 Sep;76(3):560-8. Epub 2009 Jun 9. PMID: 19509218. PMCID: PMC2730388.  Neuro

N - Berman RF, Willemsen R. Mouse models of fragile X-associated tremor ataxia.  J Investig Med. 2009 Dec;57(8):837-41. Review.  PMID: 19574928. PMCID: PMC2787904.  Neuro/mouse



N - Campbell MA, Golub MS, Iyer P, Kaufman FL, Li LH, Moran Messen F, Morgan JE, Donald JM.
Reduced water intake: Implications for rodent developmental and reproductive toxicity studies.
Birth Defects Res B Dev Reprod Toxicol. 2009 Jun;86(3):157-75. Review. PMID: 19455576. No PMCID.  Neuro/env/develop

N, G - Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC.
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.Proc Natl Acad Sci U S A. 2009 May 5;106(18):7636-41. Epub 2009 Apr 21. PMID: 19383796. PMCID: PMC2678594.  Neuro

* J, G - Enstrom A, Krakowiak P, Onore C, Pessah IN, Hertz-Picciotto I, Hansen RL, Van de Water JA, Ashwood P (2009).  
Increased IgG4 levels in children with autism disorder.
Brain Behav Immun. 23(3):389-95. (epub 2008 Dec 25)
PMID: 19136055. PMCID: PMC2696343. Immuno

* J - Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P (2009).
Altered gene expression and function of peripheral blood natural killer cells in children with autism.
Brain Behav Immun 23(1):124-33. Epub 2008 Aug 14.
PMID: 18762240. PMCID: PMC2636576. Immuno

Enstrom AM, Van de Water JA, Ashwood P. (2009)
Autoimmunity in autism.
Curr Opin Investig Drugs 10(5):463-73
PMID: 19431079. No PMCID. Immuno

N - Golub MS, Hogrefe CE, Widaman KF, Capitanio JP.
Iron deficiency anemia and affective response in rhesus monkey infants.
Dev Psychobiol. 2009 Jan;51(1):47-59.PMID: 18814183. No PMCID. Neuro/env

* Halladay AK, Amaral D, Aschner M, Bolivar VJ, Bowman A, DiCicco-Bloom E, Hyman SL, Keller F, Lein P, Pessah I, Restifo L, Threadgill DW.
Animal models of autism spectrum disorders: information for neurotoxicologists.Neurotoxicology. 2009 Sep;30(5):811-21. Epub 2009 Jul 9. PMID: 19596370. PMCID: PMC3014989. Neuro

* Hertz-Picciotto I, Delwiche L.
The rise in autism and the role of age at diagnosis. Epidemiology 20(1):84-90.
PMID: 19234401. No PMCID. Epi


* Hillyard, S.L. and J.B. German.  2009. 
Quantitative lipid analysis and life span of the fat-3 mutant of Caenorhabditis elegans. 
J. Agric Food Chem. 57:3389-3396. 
PMID 19301819. No PMCID. Env

N - Hunsaker MR, Wenzel HJ, Willemsen R, Berman RF. Progressive spatial processing deficits in a mouse model of the fragile X premutation.  Behav Neurosci. 2009 Dec;123(6):1315-24. 


PMID: 20001115. No PMCID. Neuro 


* G - Kim, K.H., Inan, S.Y., Berman, R.F. & Pessah, I.N.
Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation.Toxicology & Applied Pharmacology 2009 Jun 1;237(2): 168-177. PMID: 19289137. PMCID:  PMC2693412. Neuro/env

* G - Kim, K. H., Inan, S. Y., Berman, R. F. and Pessah I. N.  (2009)
Differential patterns of excitotoxicity and ryanodine receptor modulation in the hippocampus by two ortho-substituted polychlorinated biphenyls.
Toxicol. Appl. Pharmacol.  237(2):168-77. Epub 2009 Mar 13
PMID: 19289137. PMCID: PMC2693412. Neuro/env

* G - Lemay, D.G., D.J. Lynn, W.F. Martin, M.C. Neville, T.M. Casey, G. Rincon, E.V. Kriventseva, W.C. Barris, A.S. Hinrichs, A.J. Molenaar, K.S. Pollard, N.J. Maqboll, K. Singh, E.M. Zdobnov, R.L. Tellam, J.F. Medrano, J.B. German and M. Rijnkels. 2009. 
The bovine lactation genome: insights into the evolution of mammalian milk. Genome Biology 10(4):R43. PMID: 19393040. PMCID: PMC2688934.  Env

* G - Li, N., J-Y. Liu, V. Timofeyev, H. Qiu, S.H. Hwang, D. Tuteja, L. Lu, J. Yang, H. Mochida, R. Low, B.D. Hammock and N. Chiamvimonvat. 2009. 
Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: insight gained using metabolomic approaches. Journal of Molecular and Cellular Cardiology 47(6):835-845. PMID:  19716829. PMCID:  PMC3290524.  Env/metabolomics

* J, Jr - Morisseau, C., O. Merzlikin, A. Lin, G. He, W. Feng, I. Padilla, M.S. Denison, I.N. Pessah and B.D. Hammock. 2009. 
Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environmental Health Perspectives 117(12):1867-1872.PMID: 20049205. PMCID: PMC2799460.  Env

* J, G - Onore C, Enstrom A, Krakowiak P, Hansen R, Hertz-Picciotto I, Van de Water J (2009 Nov).
Decreased cellular IL-23 but not IL-17 production in children with autism spectrum disorders. J Neuroimmunol 216(1-2):126-9. PMID 19800697.  PMCID:  PMC2981175. Immuno

* G, P - Park H-Y, Park J-S, Sovcikova E, Kocan A, Linderholm L, Bergman Å, Trnovec T, Hertz-Picciotto I.  Exposure to hydroxylated polychlorinated biphenyls (OH-PCBs) in the prenatal period and subsequent neurodevelopment in eastern Slovakia. Environ Health Persp 2009 Oct;117(10):1600-6.  PMID: 20019912.  PMCID: PMC2790516.  Epi/env/develop/neuro

* P, Jr - Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W.
Enantiomeric Specificity of (-)-2,2',3,3',6,6'-Hexachlorobiphenyl toward Ryanodine Receptor Types 1 and 2.
Chem Res Toxicol. 2009 Jan;22(1):201-7.  PMID: 18954145. PMCID: PMC2662366.  Neuro

* Samsó, M., Feng, W., Pessah, I. N., and Allen, P. D. (2009).
Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating.
PLoS Biol.  Published online April 14, 2009; 7(4):e85. 
PMID: 19402748. PMCID: PMC2672603.  Neuro

* Sentürk D, Nguyen DV.  Partial covariate adjusted regression.J Stat Plan Inference. 2009 Feb 1;139(2):454.  PMID: 20126296. PMCID: PMC2719909. Epi




G, P - Stamova, Boryana S, Michelle Apperson, Wynn L Walker, Yingfang Tian, Huichun Xu, Peter Adamczyk, Xinhua Zhan, Da-Zhi Liu, Bradley P Ander, Isaac H Liao, Jeffrey P Gregg, Renee J Turner, Glen C Jickling, Lisa Lit and Frank R Sharp (2009).
Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood.
BMC Med Genomics 2:49
PMID: 19656400. PMCID: PMC2736983.  Gene

* J, G - Wiest MM, German JB, Harvey DJ, Watkins SM, Hertz-Picciotto I (2009).
Plasma fatty acid profiles in autism: A case-control study.
Prostaglandins, Leukot, Essent Fatty Acids. 80(4):221-7.  
PMID: 19307110. No PMCID.  Epi

* G - Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral DG, Van de Water J.
Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders.
Brain Behav Immun. 2009 Jan;23(1):64-74. Epub 2008 Jul 30.
PMID: 18706993. PMCID: PMC3313674. Immuno/neuro

* G - Yang, D., Kim, K. H., Phimister, A. V., Bachstetter, A., Ward, T., Stackman, R., Mervis, R., Wisniewski, A., Klein, S., Kodavanti, P., Anderson, Wayman, G., Pessah, I. N., and Lein, P. J. (2009).
Developmental exposure to polychlorinated biphenyls (PCBs) interferes with experience-dependent dendritic plasticity and ryanodine receptor expression in weanling rats.
Env. Health Perspect. 117, 426-435. 
PMID: 19337518. PMCID: PMC2661913.  Neuro/env

* J, P - Yingfang Tian, Peter G Green, Boryana S Stamova, Irva Hertz-Picciotto, Isaac N Pessah, Robin Hansen, Xiaowei Yang, Jeffrey P Gregg,  Paul Ashwood, Glen Jickling, Judy Van de Water and Frank R Sharp (2009). 
Correlations of Gene Expression with Blood Lead Levels in Children with Autism Compared to Typically Developing Controls. Neurotox Res 2009. [Epub ahead of print]. 
PMID: 19921347. PMCID: PMC3006638.  Gene/env


N - Zhu X, Rivera A, Golub MS, Peng J, Sha Q, Wu X, Song X, Kumarathasan P, Ho M, Redman CM, Lee S.
Changes in red cell ion transport, reduced intratumoral neovascularization, and some mild motor function abnormalities accompany targeted disruption of the Mouse Kell gene (Kel).Am J Hematol. 2009 Aug;84(8):492-8. PMID: 19544475. No PMCID.  Neuro/gene



* G - Zivkovic AM, German JB. Metabolomics for assessment of nutritional status.  Curr Opin Clin Nutr Metab Care. 2009 Sep;12(5):501-7. Review.  PMID: 19584717. PMCID: PMC2887727.  Metabolomics/translation 




* G - Zivkovic AM, Bruce German J, Esfandiari F, Halsted CH. Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease.  Alcohol Clin Exp Res. 2009 Apr;33(4):751-8. Epub 2009 Jan 21.  PMID: 19170661. No PMCID. Env/metabolomics




* G - Zivkovic, A.M., M.M. Wiest, U. Nguyen, M.L. Nording, S.M. Watkins and J.B. German.  2009. 
Assessing individual metabolic responsiveness to a lipid challenge using a targeted metabolomic approach. 
Metabolomics 5:209-208. 
PMID: 20442800.  PMCID: PMC2862503. Env/metabolomics



2008 Publications


* J, Jr - Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kültz D, Chang DPY, Gee SJ and Hammock BD (2008).
In Vitro Biological Activities of the Antimicrobials Triclocarban, its Analogues, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens.
Env Health Perspectives 116(9):1203-10. PMID: 18795164. PMCID: PMC2535623. Env

* Anderson, PJ, Lango J, Carkeet C, Britten A, Krautler B, Hammock BD and JR Roth. 2008.
One pathway can incorporate either adenine or dimethylbenzimidazole as an alpha-axial ligand of B12 cofactors in Salmonella enterica.
J Bacteriol 190:1160-1171.
PMID: 17981976. PMCID: PMC2238215. Env

* P - Aronov, P.A., L.M. Hall, K. Dettmer, C.B. Stephensen and B.D. Hammock.  2008. Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra performance liquid chromatography-tandem mass spectrometry. 
Anal. Bioanal. Chem.  Epub ahead of print. 
PMID: 18437365. No PMCID. Env

* J, G - Ashwood P, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen RL, Croen LA, Ozonoff S, Pessah IN, de Water JV.
Decreased transforming growth factor beta1 in autism: A potential link between immune dysregulation and impairment in clinical behavioral outcomes.
J Neuroimmunol 204(1-2):149-53.
PMID: 18762342. PMCID: PMC2615583.  Immuno/neuro/translation/behav

* J, G - Ashwood, P., Kwong, C., Hansen, R., Hertz-Picciotto, I., Croen, L., Krakowiak, P., Walker, W., Pessah, I.N., and Van de Water, J. 2008.
Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype?
J. Autism and Devel. Disorders, 38 (1):169-175.
PMID: 17347881. No PMCID. Immuno/gene/develop

* Berman, R. F., Pessah, I. N., Mouton, P., Mav, D., Harry, J.  (2008).
Low-level neonatal thimerosal exposure: further evaluation of altered neurotoxic potential in SJL mice.
Toxicol Sci 101(2):294-309.
PMID: 17977901. No PMCID. Neuro/env

* J, G - Braunschweig D, Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water JA (2008). 
Maternally derived antibodies specific for fetal brain proteins. 
Neurotoxicology 29(2):226-231.
PMID: 18078998.  PMCID: PMC2305723. Immuno/neuro

N - Brouwer JR, Huizer K, Severijnen LA, Hukema RK, Berman RF, Oostra BA, Willemsen R. CGG-repeat length and neuropathological and molecular correlates in a mouse model for fragile X-associated tremor/ataxia syndrome.  J Neurochem. 2008 Dec;107(6):1671-82. Epub 2008 Nov 10.  PMID: 19014369.  PMCID: PMC2605773.  Neuro



Buck Louis GM, Gray LE Jr, Marcus M, Ojeda SR, Pescovitz OH, Witchel SF, Sippell W, Abbott DH, Soto A, Tyl RW, Bourguignon JP, Skakkebaek NE, Swan SH, Golub MS, Wabitsch M, Toppari J, Euling SY.
Environmental factors and puberty timing: expert panel research needs.Pediatrics. 2008 Feb;121 Suppl 3:S192-207. PMID: 18245512. No PMCID.  Neuro/env/develop

N, Jr - Feng W, Tu J, Pouliquin P, Cabrales E, Shen X, Dulhunty A, Worley PF, Allen PD, Pessah IN. 2008.
Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1.
Cell Calcium 43(3):307-14.
PMID: 17707505. No PMCID. Neuro

* German JB, Freeman SL, Lebrilla CB, Mills DA. Human milk oligosaccharides: evolution, structures and bioselectivity as substrates for intestinal bacteria.  Nestle Nutr Workshop Ser Pediatr Program. 2008;62:205-18; discussion 218-22. Review.  PMID: 18626202. PMCID: PMC2861563. Env/gene




Golub MS, Collman GW, Foster PM, Kimmel CA, Rajpert-De Meyts E, Reiter EO, Sharpe RM, Skakkebaek NE, Toppari J.
Public health implications of altered puberty timing.
Pediatrics. 2008 Feb;121 Suppl 3:S218-30. Review.
PMID: 18245514. No PMCID.  Neuro/develop/translation

N - Grandjean P, Bellinger D, Bergman A, Cordier S, Davey-Smith G, Eskenazi B, Gee D, Gray K, Hanson M, van den Hazel P, Heindel JJ, Heinzow B, Hertz-Picciotto I, Hu H, Huang TT, Jensen TK, Landrigan PJ, McMillen IC, Murata K, Ritz B, Schoeters G, Skakkebaek NE, Skerfving S, Weihe P.
The faroes statement: human health effects of developmental exposure to chemicals in our environment.
Basic Clin Pharmacol Toxicol. 2008 Feb;102(2):73-5.
PMID: 18226057. No PMCID.  Epi/env/develop

* J - Gregg J, Lit L, Baron C, Hertz-Picciotto I, Walker W, Davis R, Croen LA, Ozonoff S, Hansen R, Pessah I, Sharp FR (2008). 
Gene expression changes in children with autism. Genomics 91(1):22-9.
PMID: 18006270.  No PMCID. Gene

* J, G, Jr - Hansen RL, Ozonoff S, Krakowiak P, Angkustsiri K, Jones C, Deprey LJ, Le D-N, Croen L, Hertz-Picciotto I (2008). 
Regression in autism: prevalence and associated factors in the CHARGE Study. 
Ambul Pediatr 8(1):25-31.
PMID: 18191778. No PMCID.  Behav/epi

* G - Hertz-Picciotto I, Jusko TA, Willman EJ, Baker RJ, Keller JA, Teplin SW, Charles MJ (2008).
A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio.
Environmental Health 7(1):37.
PMID: 18627595. PMCID: PMC2483969.  Epi/env

* G - Hertz-Picciotto I, Park H-Y, Dostal M, Kocan A, Trnovec T, Sram R (2008). 
Prenatal exposures to persistent and non-persistent organic compounds and effects on immune system development. 
Basic Clin Pharmacol Toxicol 102(2):146-54. 
PMID: 18226068. No PMCID.  Epi/immuno/env/develop

* J, G, P - Heuer L, Ashwood P, Schauer J, Goines P, Krakowiak P, Hertz-Picciotto I, Hansen R,  Croen LA,  Pessah IN, Van de Water J (2008 Oct).
Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms.  
Autism Res 1(5):275-83.  
PMID: 19343198. PMCID: PMC2663897.  Immuno/neuro/behav

* Hwang, H-M., E-K. Park, T.M. Young and B.D. Hammock.  2008. 
Occurrence of endocrine-disrupting chemicals in indoor dust. 
Sci. Total Environ. 404:26-35. 
PMID: 18632138.  No PMCID.  Env

* J, G - Krakowiak P, Goodlin-Jones B, Hertz-Picciotto I, Croen LA, Hansen RL (2008).
Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based study.
J Sleep Res. 2008 Jun;17(2):197-206.
PMID: 18482108. No PMCID. Behav/epi/develop

* G - Martin, L. A. , Ashwood, P., Braunschweig, D., Cabanlit, M., Van de Water, J., and Amaral, D.G.  2008.
Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism. 
Brain Behavior and Immunity, E-Pub ahead of print (February 2008).
PMID: 18262386. No PMCID.  Immuno/neuro/behav

N, J - Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, Lasalle JM.  2008.  
MECP2 promoter methylation and X-chromosome inactivation in autism.  
Autism Research 1(3):169-178.
PMID: 19132145.  PMCID: PMC2614877. Gene

* Nguyen DV, Senturk D and Carroll JC. 2008.
Covariate-adjusted linear mixed effects model with an application to longitudinal data.
Journal of Nonparametric Statistics 20(6):459-481.  Epi

N - Ninonuevo, M. R.; Perkins, P. D.; Francis, J.; Lamotte, L.; LoCascio, R.G.; German, J. B.; Freeman, S. L.; Grimm, R.; Lebrilla, C. B.  2008. 
Daily variations in oligosaccharides of human milk determined by microfluidic chips and mass spectrometry.
J Agric F. Chem. 2008 Jan 23;56(2):618-26.  PMID: 18088092. No PMCID.

N - Ozonoff S, Young GS, Goldring S, Greiss-Hess L, Herrera AM, Steele J, Macari S, Hepburn S, Rogers SJ. 2008.
Gross motor development, movement abnormalities, and early identification of autism.
J Autism Dev Disord 38(4):644-56.
PMID: 17805956. No PMCID. Behav/neuro/develop/translation

N - Palkovicova L, Ursinyova M, Hladikova V, Yu Z, Hertz-Picciotto I (2008). 
Maternal amalgam dental fillings as a major source of mercury in the developing fetus and newborn. 
J Expos Science & Env Epidemiol 18(3):326-31.
PMID: 17851449. No PMCID.  Epi/env

* G - Park H-Y, Hertz-Picciotto I, Petrik J, Palkovicova L, Kocan A and Trnovec T. 2008.
Prenatal PCB exposure and thymus size at birth in neonates in Eastern Slovakia.
Environ Health Perspect 116(1):104-109.
PMID:18197307. PMCID: PMC2199273.  Epi/env

* P - Park JS, Bergman A, Linderholm L, Athanasiadou M, Kocan A, Petrik J, Drobna B, Trnovec T, Charles MJ, Hertz-Picciotto I.
Placental transfer of polychlorinated biphenyls, their hydroxylated metabolites and pentachlorophenol in pregnant women from eastern Slovakia.
Chemosphere 2008 70(9):1676-84. Epub 2007 Aug 30.
PMID:17764717. PMCID: PMC2703177. Epi/env

* J - Pessah IN, Seegal RF, Lein PJ, Lasalle J, Yee BK, Van de Water J, Berman RF. (2008).
Immunologic and neurodevelopmental susceptibilities of autism.
Neurotoxicology 29(3):532-45. February 23, Epub ahead of print. 
PMID: 18394707. PMCID: PMC2475601.   Neuro/immuno/develop

N - Sakimura J.N., Dang M.T., Ballard K.B., and Hansen R.L. (2008).
Cognitive and temperament profiles in 3 to 5-year-old children with aggressive behavior.
Journal of School Health, 78(1):38-45. 
PMID: 18177299.  Behav/epi/neuro/translation

* J, G - Sonneborn D, Park HY, Babinska K, Palkovicova L, Trnovec T, Kocan A, Nguyen DV, Hertz-Picciotto I. Serum PCB concentrations in relation to locally produced food items in eastern Slovakia.
Expo Sci Environ Epidemiol. 2008 Nov;18(6):581-7. Epub 2008 Feb 20.
PMID: 18285840. No PMCID.    Epi/env

* J, G - Sonneborn, D., Park, H.-Y., Petrik, J., Kocan, A., Palkovicova, L., Trnovec, T., Nguyen, D.V. and Hertz-Picciotto, I. (2008).
Prenatal PCB exposures in Eastern Slovakia modify effects of social factors on birthweight.
Paediatric and Perinatal Epidemiology, 22, 202-213. 
PMID: 18426515. No PMCID.Epi/env

* G - Ulu, A., B.B. Davis, H-J. Tsai, I-H. Kim, C. Morisseau, B. Inceoglu, O. Fiehn, B.D. Hammock and R.H. Weiss.  2008.
Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein E-knockout mouse model. 
J. Cardiovasc. Pharmacol. 52:314-323. 
PMID: 18791465. PMCID: PMC2637359. Env/gene


* J, G - Van Meter KC, Christiansen LE, Hertz-Picciotto I, Azari R, Carpenter TE, Wills, S., Cabanlit, M., Bennett, J., Ashwood, P., Amaral, D.G., and Van de Water, J. 2008.
A procedure to characterize geographic distributions of rare disorders in cohorts.
Int J Health Geogr. 2008 May 28;7:26.
PMID: 18507863. PMCID: PMC2430550. Epi

* Vogel CF, Goth SR, Dong B, Pessah IN, Matsumura F. (2008). 
Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. 
Biochem. Biophys. Res. Commun. 375(3):331-5. 
PMID: 18694728. PMCID: PMC2583959. Neuro/env/immuno

* G - Wills, S., Cabanlit, M., Bennett, J., Ashwood, P., Amaral, D.G. and Van de Water, J. (2008).
Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders.
Brain Behavior and Immunity,23(1):64-74. E-pub Jul 30 2008.
PMID 18706993. PMCID: PMC2660333. Immuno/neuro



2007 Publications


* G, P - Cabanlit M, Wills S, Goines P, Ashwood P, Van de Water J.
Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder.
Annals of the New York Academy of Sciences, 2007. 1107:92-103.
PMID: 17804536. No PMCID.  Immuno

* Denning L, Anderson JA, Davis R, Gregg JP, Kuzdenyi J, and RA Maselli (2007).
High Throughput Genetic Analysis of Congenital Myasthenic Syndromes Using Resequencing Microarrays. 
PLoS ONE 2(9): e918.
PMID: 17878953. PMCID: PMC1975473. Gene

* P - Dettmer K, Aronov PA, Hammock BD. 2007.
Mass spectrometry-based metabolomics. Mass Spectrom Rev 26:51-78.
PMID: 16921475. PMCID: PMC1904337.  Env/metabolomics

* J, P - Dettmer K, Hanna D, Whetstone P, Hansen R, Hammock BD.
Autism and urinary exogenous neuropeptides: development of an on-line SPE-HPLC-tandem mass spectrometry method to test the opioid excess theory.
Analytical and Bioanalytical Chemistry, 2007. 388(8):1643-51.
PMID: 17520243. No PMCID. Env

* Dodds. E.D., J.B. German and C.B. Lebrilla.  2007. 
Enabling MALDI-FTICR-MS/MS for High-Performance Proteomics through Combination of Infrared and Collisional Activation. 
Anal Chem. 79:9547-9556. 
PMID: 18001128. No PMCID. Env/proteomics

* J - Enstrom A, Onore C, Tarver A, Hertz-Picciotto I, Hansen R, Croen L, Van de Water J, Ashwood P (2007). 
Detection of IL-17 and IL-23 in plasma samples of children with autism. 
Amer J Biochem Biotechnol 4:114-120. 
(ISSN 1553-3468). 
No PMID.  Immuno

* J - Enstrom A, Onore C, Tarver A, Hertz-Picciotto I, Hansen R, Croen L, Van de Water J, Ashwood P (2007).
Peripheral blood leukocyte production of BDNF following mitogen stimulation in early onset and regressive autism. 
Amer J Biochem Biotechnol 4(2):121-129. 
No PMID.  Immuno

N - Folkerts MM, Parks EA, Dedman JR, Kaetzel MA, Lyeth BG, Berman RF. 2007. Phosphorylation of calcium calmodulin-dependent protein kinase II following lateral fluid percussion brain injury in rats.
Journal of Neurotrauma. 24(4):638-50.
PMID 17439347. No PMCID.  Neuro

* G - German JB, Gillies LA, Smilowitz JT, Zivkovic AM, Watkins SM. 2007.
Lipidomics and lipid profiling in metabolomics.
Curr Opin Lipidol 18:66-71.
PMID 17218835.  No PMCID. Env/metabolomics

P - Goines, P., Schauer, J., Heuer, L., Ashwood, P., and Van de Water, J.  2007.
Beta-2-microglobulin in autism spectrum disorders.
Amer. J. Biotech. Biochem. 3:91-95.
No PMID.  Immuno


* Hertz-Picciotto I, Baker RJ, Yap PS, Dostal M, Joad JP, Lipsett M, Greenfield T, Herr CE, Benes I, Shumway RH, Pinkerton KE, Sram R. 2007.
Early childhood lower respiratory illness and air pollution.
Environ Health Perspect 115(10):1510-8.
PMID 17938744.  PMCID: PMC2022654. Epi/env

* Hillyard S.L. and J.B. German.  2007. 
Non-essential dietary factors: from test tube to lifespan. 
J. Sci. Food Agric. 87(10):1802-1805. 
No PMID.  Env

* Inceoglu B, Schmelzer KR, Morisseau C, Jinks SL, Hammock BD. 2007.
Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).
Prostaglandins Other Lipid Mediat 82(1-4):42-9.
PMID 17164131. PMCID: PMC1904338.  Env

* Kenet T, Froemke RC, Schreiner CE, Pessah IN, Merzenich MM. 2007.
Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex.
Proceedings of the National Academy of Sciences of the United States of America, 2007. 104(18):7646-51.
PMID: 17460041. PMCID: PMC1855918.  Neuro/env

* Kim, H.-J., K.C. Ahn, S.J. Ma, S.J. Gee and B.D. Hammock.  2007. 
Development of sensitive immunoassays for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroid exposure. 
J. Agr. Food Chem.  55:3750-3757.  PMID: 17455946. No PMCID.  Env

* G - Lange M.C., D.A. Lemay and J.B. German.  2007. 
A multi-ontology framework to guide agriculture and food towards diet and health.
J. Sci. Food Agric. 87(8):1427-1434. 
No PMID.  Env/translation

* G - Lemay, D.G., A.M. Zivkovic and J.B. German.  2007. 
Building the Bridges to Bioinformatics in Nutrition Research. 
Am. J. Clin. Nutr. 86:1261-1269. 
PMID: 17991634. No PMCID. Env/gene/bioinformatics

* G - Lemay, D.G., M.C. Neville, M.C. Rudolph, K.S. Pollard and J.B. German.  2007. 
Gene regulatory networks in lactation: identification of global principles using bioinformatics. 
BMC Systems Biology 1:56. 
PMID: 18039394.  PMCID: PMC2225983. Env/gene

N - Merin N, Young GS, Ozonoff S, Rogers SJ. 2007.
Visual fixation patterns during reciprocal social interaction distinguish a subgroup of 6-month-old infants at-risk for autism from comparison infants.
J Autism Dev Disord 37(1):108-21.
PMID 17191096.  No PMCID. Behav/epi/translation

N - Nadig AS, Ozonoff S, Young GS, Rozga A, Sigman M, Rogers SJ.
A prospective study of response to name in infants at risk for autism.
Arch Pediatr Adolesc Med, 2007. 161(4):378-83.
PMID: 17404135. No PMCID.  Behav/epi/translation

* Newman, J.W., G.A. Kaysen, B.D. Hammock and G.C. Shearer.  2007. 
Proteinuria increases oxylipid concentrations in VLDL and HDL, but not LDL particles in the rat. 
J. Lipid Res.  48:1792-1800. 
PMID: 17496268. No PMCID. Env

* Ninonuevo, M.R., Ward, R.E., LoCascio, R.G., German, J.B., Freeman, S.L, Barboza, M, Mills, D.A. and Lebrilla, C.B.  2007. 
Methods for the quantitation of human milk oligosaccharides in bacterial fermentation by mass spectrometry. Analytical Biochemistry 361:15–23.
PMID:  17218835.  No PMCID. Env

* Nguyen DV and Senturk D. 2007.
Distortion diagnostics for covariate-adjusted regression: graphical techniques based on local linear modeling.
Journal of Data Science 5:471-490.
No PMID.  Epi

* Ninonuevo MR, Ward RE, LoCascio RG, German JB, Freeman SL, Barboza M, Mills DA, Lebrilla CB. 2007.
Methods for the quantitation of human milk oligosaccharides in bacterial fermentation by mass spectometry.
Anal Biochem 361:15-23.
PMID 17181994. No PMCID.   Env

* Ostrovskaya O, Goyal R, Osman N, McAllister CE, Pessah IN, Hume JR, Wilson SM. 2007.
Inhibition of ryanodine receptors by 4-(2-aminopropyl)-3,5-dichloro-N,N-dimethylaniline (FLA 365) in canine pulmonary arterial smooth muscle cells.
J Pharmacol Exp Ther 323(1):381-90.
PMID:17640951. No PMCID.  Neuro

* J - Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD, Pessah IN.
Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.
Journal of Biological Chemistry, 2007. 282:8667-77.
PMID: 17237236.  No PMCID. Neuro

N, G - Ran R, Pan R, Lu A, Xu H, Davis RR, Sharp FR. 2007.
A novel 165-kDa Golgin protein induced by brain ischemia and phosphorylated by Akt protects against apoptosis.
Mol Cell Neurosci 36(3):392-407.
PMID: 17888676. No PMCID.  Gene/neuro

* Ta, T. A., and Pessah, I. N.  (2007).
Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95).
Neurotoxicology 28(4):770-779. (Cover Article).
PMID 17023049.  PMCID: PMC2274001. Neuro/env

* Ward R.E., M. Niñonuevo, D.A. Mills, C.B. Lebrilla and J.B. German.  2007. 
In vitro fermentability of human milk oligosaccharides by several strains of bifidobacteria. 
Mol. Nutr. Food Res. 51(11):1398-405. 
PMID: 17966141. No PMCID. Env

N, G - Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral D, Van de Water J. 2007. Autoantibodies in autism spectrum disorders (ASD).
Annals of the New York Academy of Sciences, 1107:79-91.
PMID: 17804535.  No PMCID. Immuno

N - Yang T, Allen PD, Pessah IN, Lopez JR. 2007.
Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RYR1 MH mutations.
The Journal of Biological Chemistry 282(52):37471-8.
PMID: 17942409.  No PMCID. Neuro

N - Yang T, Esteve E, Pessah IN, Molinski TF, Allen PD, López JR. Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR.  Am J Physiol Cell Physiol. 2007 May;292(5):C1591-8. Epub 2006 Dec 20.  PMID: 17182726. No PMCID. Neuro




2006 Publications




* Baron CA, Tepper CG, Liu SY, Davis RR, Wang NJ, Schanen NC, Gregg JP. 2006.
 Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes. Hum Mol Genet 15:853-69
PMID: 16446308. No PMCID. Gene



* Baron CA, Liu SY, Hicks C, Gregg JP.
Utilization of lymphoblastoid cell lines as a system for the molecular modeling of autism.
J Autism Dev Disord, 2006. 36(8):973-82.
PMID: 16845580. No PMCID. Gene

* Bu B, Ashwood P, Harvey D, King IB, Water JV, Jin LW. 2006.
Fatty Acid Compositions of Red Blood Cell Phospholipids in Children With Autism.
Prostaglandins Leukot Essent Fatty Acids 74:215-21
PMID: 16581239. No PMCID.  Epi/neuro/env

* Burke K, Cheng Y, Li B, Petrov A, Joshi P, Berman RF, Reuhl KR, DiCicco-Bloom E. 2006.
Methylmercury Elicits Rapid Inhibition of Cell Proliferation in the Developing Brain and Decreases Cell Cycle Regulator, Cyclin E.
Neurotoxicology 27:970-81.  PMID: 17056119. PMCID: PMC2013736. Neuro/env

* Carkeet C, Dueker SR, Lango J, Buchholz BA, Miller JW, Green R, Hammock BD, Roth JR, Anderson PJ. 2006.
Human Vitamin B12 Absorption Measurement By Accelerator Mass Spectrometry Using Specifically Labeled (14)C-cobalamin
Proc Natl Acad Sci U S A 103:5694-9.
PMID: 16585531. No PMCID.  Env

* Chelu MG, Goonasekera SA, Durham WJ, Tang W, Lueck JD, Riehl J, Pessah IN, Zhang P, Bhattacharjee MB, Dirksen RT, Hamilton SL.
Heat- and anesthesia-induced malignant hyperthermia in a RyR1 knock-in mouse
FASEB Journal, 20(2):329-330.
PMID: 16284304.  No PMCID. Neuro

* Dai JJ, Lieu L, Rocke D. 2006.
Dimension Reduction for Classification With Gene Expression Microarray Data.
Stat Appl Genet Mol Biol 5:Article6.
PMID: 16646870. No PMCID.  Epi

* Davis BB, Morisseau C, Newman JW, Pedersen TL, Hammock BD, Weiss RH. 2006.
Attenuation of Vascular Smooth Muscle Cell Proliferation By 1-Cyclohexyl-3-Dodecyl Urea Is Independent of Soluble Expoxide Hydrolase Inhibition.
J Pharmacol Exp Ther 316:815-21
PMID: 16221742. PMCID: PMC1456012.  Env

* J, G - Du X, Tang Y, Xu H, Lit L, Walker W, Ashwood P, Gregg JP, Sharp FR. 2006.
Genomic Profiles for Human Peripheral Blood T Cells, B Cells, Natural Killer Cells, Monocytes.
Genomics 87:693-703
PMID: 16546348.  No PMCID. Gene/immuno

G - German, J.B., Dillard, C.J., Hillyard, S.L., Lange, M.C., Smilowitz, J.T., Ward, R.E., Zivkovic, A.M.  2006. 
Metabolomics: Bringing nutrigenomics to practice in individualized health assessment. In Nutritional Genomics. Eds Jim Kaput & Raymond Rodriguez. John Wiley & Sons, New Jersey. Pg. 85-104.  Gene/metabolomics/translation



* G - German JB, Smilowitz JT, Zivkovic AM. Lipoproteins: When size really matters.  Curr Opin Colloid Interface Sci. 2006 Jun;11(2-3):171-183.  PMID: 20592953. PMCID: PMC2893739. Env




* J, Jr - Goth SR, Chu RA, Gregg JP, Cherednichenko G, and Pessah IN.
Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal.
Environ Health Perspect. 2006 Jul;114(7):1083-91.
PMID: 16835063. PMCID: PMC1513334.  Neuro/immuno/env

* J - Hertz-Picciotto I, Croen LA, Hansen R, Jones CR, van de Water J, Pessah IN.
The CHARGE Study: An Epidemiologic Investigation of Genetic and Environmental Factors Contributing to Autism.
Environ Health Perspect. 2006 Jul;114(7):1119-25.
PMID: 16835068.  PMCID: PMC1513329.  Epi

* Howards PP, Hertz-Picciotto I. 2006.
Invited Commentary: Disinfection By-Products and Pregnancy Loss--Lessons.
Am J Epidemiol 164:1052-5.
PMID: 16957028. No PMCID.  Epi/env/translation

* Huang H, Nishi K, Gee SJ, Hammock BD. 2006.
Evaluation of Chiral Alpha-Cyanoesters AS General Fluorescent Substrates for Screening Enantioselective Esterases.
J Agric Food Chem 54:694-9.
PMID: 16448170. PMCID: PMC1444886.  Env

* G - Jusko TA, Koepsell TD, Baker RJ, Greenfield TA, Willman EJ, Charles MJ, Teplin SW, Checkoway H, Hertz-Picciotto I. 2006.
Maternal DDT Exposures in Relation To Fetal and 5-Year Growth.
Epidemiology 17:692-700.
PMID: 17003683. No PMCID. Epi/env

* Li L. 2006.
Survival Prediction of Diffuse Large-B-Cell Lymphoma Based On Both Clinical and Gene Expression Information.
Bioinformatics 22:466-71.
PMID: 16339281. No PMCID. Epi/bioinformatics

* Masuno MN, Pessah IN, Olmstead MM, Molinski TF. 2006.
Simplified Cyclic Analogues of Bastadin-5. Structure-Activity Relationships for Modulation. 
J Med Chem 49:4497-511.
PMID: 16854055. No PMCID.  Neuro

* Ninonuevo MR, Park Y, Yin H, Zhang J, Ward RE, Clowers BH, German JB, Freeman SL, Killeen K, Grimm R, Lebrilla CB. 2006.
A Strategy for Annotating the Human Milk Glycome.
J Agric Food Chem 54:7471-80.
PMID:17002410. No PMCID. Env

* G, P - Pessah IN, Hansen LG, Albertson TE, Garner CE, Ta TA, Do Z, Kim KH, Wong PW. 2006.
Structure-Activity Relationship for Noncoplanar Polychlorinated Biphenyl Congeners Toward the Ryanodine Receptor-Ca2+ Channel Complex Type 1 (RyR1).
Chem Res Toxicol 19:92-101.
PMID: 16411661. No PMCID. Neuro/env

* Schmelzer KR, Inceoglu B, Kubala L, Kim IH, Jinks SL, Eiserich JP, Hammock BD. 2006.
Enhancement of Antinociception by Coadministration of Nonsteroidal Anti-Inflammatory Drugs and soluble epoxide hydrolase inhibitors.
Proc Natl Acad Sci USA 103(37):13646-51.
PMID: 16950874. PMCID: PMC1564210.  Env

* P - Schmelzer KR, Wheelock AM, Dettmer K, Morin D, Hammock BD. 2006.
The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways.
Environ Health Perspect 114(9):1354-60.
PMID: 16966088. PMCID: PMC1570074. Env

* P, Jr - Ta TA, Feng W, Molinski TF, Pessah IN. Hydroxylated xestospongins block inositol-1,4,5-trisphosphate-induced Ca2+ release and sensitize Ca2+-induced Ca2+ release mediated by ryanodine receptors.  Mol Pharmacol. 2006 Feb;69(2):532-8. Epub 2005 Oct 25.  PMID: 16249374. No PMCID. Neuro 




* Ward RE, Niñonuevo M, Mills DA, Lebrilla CB, German JB. 2006.
In Vitro Fermentation of Breast Milk Oligosaccharides by Bifidobacterium infantis and Lactobacillus gasseri. Appl Environ Microbiol 72:4497-9.
PMID: 16751577. PMCID: PMC1489581.  Env

* Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR. 2006.
Pharmacologic and Functional Characterization of Malignant Hyperthermia in the R163c Ryr1 Knock-In Mouse.
Anesthesiology 105:1164-75.
PMID: 17122579. No PMCID.  Neuro



2005 Publications Not Listed in Previous Renewal


* Fang X, Hu S, Watanabe T, Weintraub NL, Snyder GD, Yao J, Liu Y, Shyy JY, Hammock BD, Spector AA.
Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors.
J Pharmacol Exp Ther. 2005 Jul;314(1):260-70. Epub 2005 Mar 29.
PMID: 15798002. PMCID: PMC1450258. Env



* Gibney MJ, Walsh M, Brennan L, Roche HM, German B, van Ommen B.  Metabolomics in human nutrition: opportunities and challenges.  Am J Clin Nutr. 2005 Sep;82(3):497-503. Review.  PMID: 16155259. No PMCID. Env/metabolomics




* Hertz-Picciotto I, Charles MJ, James RA, Keller JA, Willman E, Teplin S.
In utero polychlorinated biphenyl exposures in relation to fetal and early childhood growth. Epidemiology. 2005 Sep;16(5):648-56.
PMID: 16135941. No PMCID.  Epi/env/develop



N - López JR, Linares N, Pessah IN, Allen PD. Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i.  Am J Physiol Cell Physiol. 2005 Mar;288(3):C606-12. Epub 2004 Nov 10. 


PMID: 15537710. No PMCID. Neuro 


* Shearer GC, Newman JW, Hammock BD, Kaysen GA.
Graded effects of proteinuria on HDL structure in nephrotic rats.
J Am Soc Nephrol. 2005 May;16(5):1309-19. Epub 2005 Mar 23.
PMID: 15788471. PMCID: PMC1456011.  Env

Smilowitz, J. T., Dillard, C. J. and German, J. B.
Milk beyond essential nutrients: the metabolic food.
Australian Journal of Dairy Technology 60 (2): 77-83 JUL 2005.
No PMID.  Env



2004 Publications Not Listed in Previous Renewal


* Bauman MD, Lavenex P, Mason WA, Capitanio JP, Amaral DG.  The development of social behavior following neonatal amygdala lesions in rhesus monkeys.  J Cogn Neurosci. 2004 Oct;16(8):1388-411.  PMID: 15509386. No PMCID. Neuro 




2003 Publications Not Listed in Previous Renewal


* Estève E, Smida-Rezgui S, Sarkozi S, Szegedi C, Regaya I, Chen L, Altafaj X, Rochat H, Allen P, Pessah IN, Marty I, Sabatier JM, Jona I, De Waard M, Ronjat M.  Critical amino acid residues determine the binding affinity and the Ca2+ release efficacy of maurocalcine in skeletal muscle cells.  J Biol Chem. 2003 Sep 26;278(39):37822-31. Epub 2003 Jul 17.  PMID: 12869557.  No PMCID. Neuro 



Aronov, P.A., K. Dettmer, J.A. Christiansen, A.J. Cornel and B.D. Hammock
Development of a HPLC/tandem-MS method for the analysis of the larvicides methoprene, hydroprene and kinoprene at trace levels using Diels-Alder derivatization
J. Agric. Food Chem, 2005. 53:3306-3312.
PMID 15853364

Croen LA, Grether JK, Yoshida CK, Odouli R, Van de Water J.
Maternal autoimmune diseases, allergy and asthma and childhood autism.
Arch Pediatr Adolesc Med, 2005. 159:151-157.
PMID 15699309

Dietrich, K.M., Eskenazi, B., Shantz, S., Yolton, K., Rauh, V.A., Johnson, C.B., Alkon, A., Canfield, R.L., Pessah, I.N., Berman, R.F.
Principles and practices of neurodevelopmental assessment in environmental health: From the Centers for Children's Environmental Health and Disease prevention research.
Environ Health Perspect. 2005 113(10):1437-46.
PMID 16203260

Fang X, Hu S, Watanabe T, Weintraub NL, Snyder GD, Yao J, Liu Y, Shyy JY, Hammock BD, Spector AA.
Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors.
J Pharmacol Exp Ther. 2005 Jul;314(1):260-70. Epub 2005 Mar 29.
PMID 15798002

German, J.B., B.D. Hammock and S.M. Watkins.  2005. 
Metabolomics:  building on a century of biochemistry to guide human health. 
Metabolomics 1:3-9.
PMC 1457093

German, J.B., Watkins, S.M. and Fay, L-B.
Metabolomics in Practice: Emerging Knowledge to Guide Future Dietetic Advice toward Individualized Health.
J. Am. Diet. Assoc. 2005 Sep;105(9):1425-32.
PMID 16129085

Gibney, M. J., Walsh, M., Brennan, L., Roche, H.M., German, B. , van Ommen, B.
Metabolomics in human nutrition: opportunities and challenges.
Am J Clin Nutr. 2005 82(3):497-503
PMID 16155259

Hertz-Picciotto I, Charles MJ, James RA, Keller JA, Willman E, Teplin S.
In utero polychlorinated biphenyl exposures in relation to fetal and early childhood growth.
Epidemiology. 2005 Sep;16(5):648-56.
PMID 16135941 (Abstract only)

Huang H, Stok JE, Stoutamire DW, Gee SJ, Hammock BD.
Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases.
Chem Res Toxicol. 2005 Mar;18(3):516-27.
PMID 15777092

Hurne AM, O'Brien JJ, Wingrove D, Cherednichenko G, Allen PD, Beam KG, Pessah IN.
Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion.
J Biol Chem. 2005 Nov 4;280(44):36994-7004. Epub 2005 Aug 24.
PMID 16120606

Inceoglu, B., J. Lango, I.N. Pessah and B.D. Hammock.
Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity.
Toxicon., 2005. 45:727-733.
PMID 15804521

Kim, I.-H., F.R. Heirtzler, C. Morisseau, K. Nishi, H.-J. Tsai, B.D. Hammock.
Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility.
J. Med. Chem., 2005. 48:3621-3629.
PMID 15887969

Kostyniak PJ, Hansen LG, Widholm JJ, Fitzpatrick RD, Olson JR, Helferich JL, Kim KH, Sable HJ, Seegal RF, Pessah IN, Schantz SL.
Formulation and characterization of an experimental PCB mixture designed to mimic human exposure from contaminated fish.
Toxicol Sci. 2005 Dec;88(2):400-11. Epub 2005 Sep 21.
PMID 16177234

Newman, J.W., C. Morisseau and B.D. Hammock.
Epoxide hydrolases: Their roles and interactions with lipid metabolism.
Prog. Lipid Res., 2005. 44:1-51.
PMID 15748653

Pessah IN, Hansen LG, Albertson TE, Garner CE, Ta TA, Do Z, Kim KH, and Wong PW.
Structure-activity relationship for Noncoplanar Polychlorinated Biphenyl Congeners toward the Ryanodine Receptor-Ca2+ Channel Complex Type 1 (RyR1).
Chem Res Toxicol, 2005. 19:92-101.
View Article

Schmelzer KR, Kubala L, Newman JW, Kim IH, Eiserich JP, Hammock BD.
Soluble epoxide hydrolase is a therapeutic target for acute inflammation.
Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9772-7. Epub 2005 Jun 30.
PMID 15994227

Shearer GC, Newman JW, Hammock BD, Kaysen GA.
Graded effects of proteinuria on HDL structure in nephrotic rats.
J Am Soc Nephrol. 2005 May;16(5):1309-19. Epub 2005 Mar 23.
PMID 15788471

Smilowitz, J. T., Dillard, C. J. and German, J. B.
Milk beyond essential nutrients: the metabolic food.
Australian Journal of Dairy Technology 60 (2): 77-83 JUL 2005.
No PMID. Smith, K.R., K.E. Pinkerton, T. Watanabe, T.L. Pedersen, S.J. Ma and B.D. Hammock.
Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor.
PNAS, 2005. 102:2186-2191.
PMID 15684051

Yang W, Yaoi T, Huang S, Yang Q, Hatcher S, Seet H, Gregg JP.
Detecting the C282Y and H63D mutations of the HFE gene by Holliday Junction-based allele- specific genotyping methods.
Clin Chem., 2005. Jan;51(1):210-3.
View Article


Aleman M, Riehl J, Aldridge BM, LeCouteur RA, Stott JL, and Pessah, IN
Association of a mutation in the ryanodine receptor 1 gene with equine malignant hyperthermia.
Muscle and Nerve, 2004. 30(3): 356-365.
PMID 15318347.

Ashwood, P., Van de Water, J.
Is autism an autoimmune disease?
Autoimmune Reviews, 2004. v.3, pp. 557-562.
View Article

Brown DuTeaux, S., Newman, J.W., Morisseau, C., Fairburn, E.A., Jelks, K., Hammock, B.D., Miller, M.G.
Epoxide hydrolase in the rat epididymis: Possible roles in xenobiotic and endogenous fatty acid metabolism.
Toxicological Sciences, 2004. v.78, no.2, pp.187-195.
View Article 

Cherednichenko G, Hurne A, Fessenden JD, Lee EH, Allen PD, Beam KG, and Pessah IN.
Conformational activation of Ca2+ entry by depolarization of skeletal myotubes.
Proc. Natl. Acad. Sci. USA 101, 2004.
November 2; 101(44): 15793-15798.
View Article

Cherednichenko, G., Zima, A.V., Feng,W., Schaefer, S., Blatter, L.A., I.N. Pessah.
NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release.
Circulation Research, 2004. v.94, pp. 478-486.
View Article 

Dey, A., R.S. Williams, D.M. Pollock, D.W. Stepp, J.W. Newman, B.D. Hammock and J.D. Imig.
Altered kidney CYP2C and increased Cyclooxygenase-2 levels are associated with obesity- related Albuminuria.
Obes. Res., 2004. 12:1278-1289.
View Article 

Hammock, B.D., and A.A. Spector.
Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels.
Am. J. Physiol.-Heart C., 2004. 287:H2412-H2420.
View Article 

Huang, H., J.E. Stok, D.W. Stoutamire, S.J. Gee and B.D. Hammock.
Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases.
Chem. Res. Toxicol., 2004. 18:516-527
View Article

Kim, I., Morisseau, C., Watanabe, T., Hammock, B.D. Journal of Medicinal Chemistry, 2004. v.47, no.8, pp. 2110-2122.
Design, synthesis, and biological activity of 1,3-distributed ureas and potent inhibitors of the soluble epoxide hydrolase of increased water solubility.
View Article

Lawler CP, Croen LA, Grether JK, Van de Water J.
Identifying environmental contributions to autism: provocative clues and false leads.
MRDD Research Reviews, 2004. 10:292-302.
View Article

Li L, Li H.
Dimension Reduction Methods for Microarrays with Application to Censored Survival Data.
Bioinformatics, 2004. 20:3406-3412.
View Article

Ward, C.W., Feng, W., Tu, J., Pessah, I.N., Worley, P.K., Schneider, M.F.
Homer protein increases activation of Ca2+ sparks in permeabilized skeletal muscle.
Journal of Biological Chemistry, 2004. v.279, no.7, pp. 5781-5787.
View Article

Voss AA, Lango J, Ernst-Russell M, Morin D, and Pessah IN.
Identification of hyperreactive cysteines within ryanodine receptor type 1 by mass spectrometry.
J. Biol. Chem., 2004. 279, 34514-20.
View Article

Zhao, X., Yamamoto, T., Newman, J.W., Kim, I., Watanabe, T., Hammock, B.D., Stewart, J., Pollock, J.S., Pollock, D.M., Imig, J.D.
Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.
Journal of the American Society of Nephrology, 2004. v.15, pp.1244-1253.
View Article


Chen, L., Estece, E., Sabatier, J.M., Ronjat, M., De Waard, M., Allen, P.D., Pessah, I.N.
Maurocalcine and peptide A stabilize distinct subconductance states of ryandodine receptor type 1, revealing a proportional gating mechanism.
Journal of Biological Chemistry, 2003. v.287, no.18, pp.16095-16106.
View Article

Gafni, J., Wong, P.W., Pessah, I.N.
Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors.
Toxicological Sciences, 2003. v.77, no.1, pp.72-82.
View Article

Gellar, S.C., Gregg J.P., Hagerman, P., Rocke, D.M.
Transformation and normalization of oglionucleotide microarray data.
Bioinformatics, 2003. v.19, no.14, pp. 1817-1823.
View Article

Howard, A.S., Fitzpatrick, R., Pessah, I., Kostyniak, P., Lein, P.J.
Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor.
Toxicology and Applied Pharmacology, 2003. v.190, pp.72-86.
View Article

Newman, J.W., Morisseau, C., Harris, T.R., Hammock, B.D.
The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate activity.
Proceedings of the National Academy of Sciences, 2003. v.100, pp. 1558-1563.
View Article

Viswanathan, S., Hammock, B.C., Newman, J.W., Meerarani, P., Toborek, M., Hennig, B.
Involvement of CYP 2C9 in Mediating the proinflammatory effects of linoleic acid in vascular endothelial cells.
Journal of the American College of Nutrition, 2003. v.22, no.6, pp. 502-510.
View Article 


Fang, X., Weintraub, N.L., Oltman, C.L., Stroll, L.L., Kaduce, T.L., Harmon, S., Dellsperger, K.C., Morisseau, C., Hammock, B.D., Spector, A.A.
Human coronary endothelial cells convert 14, 15-EET to a biologically active chain-shortened epoxide.
American Journal of Physiology-Heart and Circulation Physiology, 2002. v.283, no.6, pp. H2306-H2314.
PMID 12388281

Feng, W., Tu, J., Yang, T., Vernon, P.S., Allen, P.D., Worley, P.F., Pessah, I.N.
Homer regulates gain of ryanodine receptor type 1 channel complex.
Journal of Biological Chemistry, 2002. v.227, no.47, pp.44722-44730.
View Article

Newman, J.W., Watanabe, T., Hammock, B.D.
The simultaneous quantification of cytochrome P450 dependant linoleate and arachidonate and arachadonite metabolites in urine by HPLC-MS/MS.
Journal of Lipid Research, 2002. v.43, no.9, pp.1563-1578.
View Article 

Shan, G., Lipton, C., Gee, S.J., Hammock, B.D.
Immunoassays, biosensors and other nonchromatographic methods.
In: Handbook of Residue Analytical Methods for Agrochemicals (Lee, P.W. ed.), 2002. pp.623-679, John Wiley & Sons, Ltd. Chichester.