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Are you interested in learning what happens to all of the data collected from our clinical trials?  Click on each of the bars below to see our publications!

General Translational Medicine
  • Kol, A., Arzi, B., Athanasiou, K.A., Farmer, D.L., Nolta, J.A., Rebhun, R.B., Chen, X., Griffiths, L.G., Verstraete, F.J.M., Murphy, C.J., & Borjesson, D.L. (2015).  Companion animals: Translational scientist's new best friends. Science Translational Medicine,  7(308), 1-8 (DOI: 10.1126/scitranslmed.aaa9116)
  • Lairmore, M.D., & Khanna, C. (2014). "Naturally Occurring Diseases in Animals: Contributions to Translational Medicine". Institute of Laboratory Animal Research, 55(1): 1-3. (DOI:10.1093/ilar/ilu022)
Anesthesia & Pain Management
  • Guedes, A.G.P., Morisseau, C., Sole, A., Soares, J.H.N., Ulu, A., Dong, H., & Hammock, B.D. (2013). "Use of a soluable epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis". Veterinary Anaesthesia and Analgesia, ePub, 7 Mar 2013. (DOI:10.1111/vaa.12030)
  • Woodhouse, K.J., Brosnan, R.J., Nguyen, K.Q., Moniz, G.W., & Galuppo, L.D. (2013). Effects of postanesthetic sedation with romifidine or xylazine on quality of recovery from isoflurane anesthesia in horses. Journal of the American Veterinary Medical Association, 242(4), 533-539. (DOI: 10.2460/javma.242.4.533)
  • Bain, M.J., Hart, B.L., Cliff, K.D. & Ruehl, W.W. (2001). Prevalence of behavioral changes associated with age-related cognitive impairment in dogs. Journal of the American Veterinary Medical Association, 218(11), 1792-5. (DOI:10.2460/javma.2001.218.1792)
  • Bergman, L., Hart, B.L., Bain, M.J., & Cliff, K. (2002). Evaluation of urine marking by cats as a model for understanding veterinary diagnostic and treatment approaches and client attitudes. Journal of the American Veterinary Medical Association, 221(9), 1282-86. (DOI:10.2460/javma.2002.221.1282)
  • Gaskins, L.A., & Bergman, L. (2011). Surveys of Avian Practitioners and Pet Owners Regarding Common Behavior Problems in Psittacine Birds. Journal of Avian Medicine and Surgery, 25(2), 111-8. (DOI:
  • Hart, B.L. (2001). Effect of gonadectomy on subsequent development of age-related cognitive impairment in dogs. Journal of the American Veterinary Medical Association, 219(1), 51-56. (DOI:10.2460/javma.2001.219.51)
  • Hart, B.L., Cliff, K.D., Tynes, V.V. & Bergman, L. (2005). Control of urine marking by use of long-term treatment with fluoxetine or clomipramine in cats. Journal of the American Veterinary Medical Association, 226(3), 378-82. (DOI:10.2460/javma.2005.226.378)
  • Helms, T.D. & Bain, M.J. (2009). Evaluation of owner attachment to dogs on the basis of whether owners are legally considered guardians of their pets. Journal of the American Veterinary Medical Association, 234(7), 896-900. (DOI:10.2460/javma.234.7.896)
  • Kwan, J.Y., & Bain, M.J. (2013). Owner Attachment and Problem Behaviors Related to Relinquishment and Training Techniques of Dogs. Journal of Applied Animal Welfare Science, 16(2), 168-83. (DOI:10.1080/10888705.2013.768923)
  • Malamed, R., Berger, J., Bain, M.J., Kass, P., & Spier, S.J. (2011). Retrospective evaluation of crib-biting and windsucking behaviours and owner-perceived behavioural traits as risk factors for colic in horses. Equine Veterinary Journal, 42(8), 686-92. (DOI:10.1111/j.2042-3306.2010.00096.x)
  • Neilson, J.C., Hart, B.L., Cliff, K.D., & Ruehl, W.W. (2001). Prevalence of behavioral changes associated with age-related cognitive impairment in dogs. Journal of the American Veterinary Medical Association, 218(11), 1787-91. (DOI:10.2460/javma.2001.218.1787)
  • Pryor, P.A., Hart, B.L., Cliff, K. & Bain, M.J. (2001). Effects of a selective serotonin reuptake inhibitor on urine spraying behavior in cats. Journal of the American Veterinary Medical Association, 221(11), 1557-61. (DOI:10.2460/javma.2001.219.1557)
  • Pryor, P.A., Hart, B.L., Bain, M.J. & Cliff, K. (2001). Causes of urine marking in cats and effects of environmental management on frequency of marking. Journal of the American Veterinary Medical Association, 219(12), 1709-13. (DOI:10.2460/javma.2001.219.1709)
  • Segurson, S.A., Serpell, J.A., & Hart, B.L. (2005). Evaluation of a behavioral assessment questionnaire for use in the characterization of behavioral problems of dogs relinquished to animal shelters. Journal of the American Veterinary Medical Association, 227(11), 1755-61. (DOI:10.2460/javma.2005.227.1755)
  • Stepita, M.E., Bain, M.J., & Kass, P.H. (2013). Frequency of CPV Infection in Vaccinated Puppies that Attended Puppy Socialization Classes. Journal of the American Animal Hospital Association, 49(2), 95-100. (DOI:1053526/JAAHA-MS-5825)
  • Sueda, K.L.C., Hart, B.L., & Cliff, K.D. (2008).  Characterisation of plant eating in dogs.  Applied Animal Behaviour Science, 111(1-2), 120-132.  (DOI:10.1016/j.applanim.2007.05.018)
  • Takeuchi, Y., Kaneko, F., Hasizume, C., Masuda, K., Ogata, N., Maki, T., Inoue-Muramyama, M., Hart, B.L., & Mori, Y. (2009).  Association analysis between canine behavioural traits and genetic polymorphisms in the Shiba Inu breed.  Animal Genetics, 40(5), 616-622.  (DOI:10.1111/j.1365-2052.2009.01888.x)
  • Torres de la Riva, G., Hart, B.L., Farver, T.B., Oberbauer, A.M., Messam, L.L.M., Willits, N., & Hart, L.A. (2013). Neutering Dogs: Effects on Joint Disorders and Cancers in Golden Retrievers. Public Library of Science One, 8(2), e55937. (DOI:10.1371/journal.pone.0055937)
  • Tynes, V.V., Hart, B.L. & Bain, M.J. (2007). Human-directed aggression in miniature pet pigs. Journal of the American Animal Hospital Association, 230(3), 385-89. (DOI:10.2460/javma.230.3.385)
  • Tynes, V.V., Hart, B.L., Pryor, P.A., Bain, M.J., & Messam, L.L.M. (2003). Evaluation of the role of lower urinary tract disease in cats with urine-marking behavior. Journal of the American Veterinary Medical Association, 223(4), 457-61. (DOI:10.2460/javma.2003.223.457)
Cardiology (Heart)
  • Stern, J.A., White, S.N., Lehmkuhi, L.B., Reina-Doreste, Y., Ferguson, J.L., Nascone-Yodeer, N.M., & Meurs, K.M. (2014). A single codon insertion in PICALM is associated with development of familial subvalvular aortic stenosis in Newfoundland dogs. Human Genetics, 133(9), 1139-48. (DOI: 10.007/s00439-014-1454-0)
Dentistry and Oral Surgery (Mouth and Face)
  • Arzi, B., Mills-Ko, E., Verstraete, F.J.M., Kol, Amir, Walker, N.J., Badgley, M.R., Fazel, N., Murphy, W.J., Vapniarsky, N., & Borjesson, D.L. (2016).  Therapeutic Efficacy of Fresh, Autologous Mesenchymal Stem Cells for Severe Refractory Gingivostomatitis in Cats.  Stem Cells Translational Medicine, 5:1-12.  (DOI: 10.5966/sctm.2015-0127)
  • Arzi, B., Kol, A., Murphy, B., Walker, N.J., Wood, J.A., Clark, K., Verstraete, F.J.M., & Borjesson, D.L. (2015)  Feline Foamy Virus Adversely Affects Feline Mesenchymal Stem Cell Culture and Expansion: Implications for Animal Model Development.  Stem Cells and Development, 24(7): 814-23. (DOI: 10.1089/scd.2014.0317)
  • Arzi, B. & Verstraete, F.J.M. (2014). Internal Fixation of Severe Maxillofacial Fractures in Dogs. Veterinary Surgery, ePub, 11 Feb 2014 (DOI: 10.1111/j.1532-950X.2014.12161.x)
  • Arzi, B. & Verstraete, F.J.M. (2014). Regenerating Mandibular Bone Using rhBMP-2: Part 1 - Immediate Reconstruction of Segmental Mandibulectomies. Veterinary Surgery, ePub, 10 Jan 2014 (DOI: 10.1111/j.1532-950X.2014.12123.x)
  • Farcas, N., Lommer, M.J., Kass, P.H., & Verstraete, F.J.M. (2014). Dental radiographic findings in cats with chronic gingivostomatitis (2002-2012). Journal of the American Veterinary Medical Association, 244, 339-45. (DOI: 10.2460/javma.244.3.339)
  • Henry, T., Pusterla, N., Guedes, A.G., & Verstraete, F.J.M. (2014). Evaluation and clinical use of an intraoral inferior alveolar nerve block int he horse. Equine Veterinary Journal, ePub, 22 Nov 2013. (DOI: 10.1111/evj.12219)
  • Loutonen, N., Kuntsi-Vaattovaara, H., Sarkiala-Kessel, E., Junnila, J.J.T., Laitinen-Vapaavuori, O., & Verstraete, F.J.M. (2014). Vital pulp therapy in dogs: 190 cases (2001-2011). Journal of the American Veterinary Medical Association, 244 (4); 449-59. (DOI: 10.2460/javma.244.4.449)
  • Nemec, A., Daniaux, L., Johnson, E., Peralta, S., & Verstraete, F.J.M. (2014). Craniomaxillofacial Abnormalities in Dogs with Congenital Palatal Defects: Computed Tomographic Findings.  Veterinary Surgery, ePub 16 Jan 2014 (DOI: doi: 10.1111/j.1532-950X.2014.12129.x.)
  • Peralta, S., Nemec, A., Fiani, N., & Verstraete, F.J.M. (2014). Staged Double-Layer Closure of Palatal Defects in 6 Dogs. Veterinary Surgery, ePub, 29 Jan 2014. (DOI:10.1111/j.1532-950X.2014.12131.x.)
  • Verstraete, F.J.M., Arzi, B., Huey, D.J., Cissell, D.D., & Kyriacos, A. (2014). Regenerating Mandibular Bone Using rhBMP-2: Part 2 - Treatment of Chronic, Defect Non-Union Fractures. Veterinary Surgery, ePub, 10 Jan 2014. (DOI: 10.1111/j.1532-950X.2014.12122.x)
  • Pedersen, N.C., Brucker, L., Green Tessier, N., Liu, H., Penedo, M.C.T., Hughes, S., Oberbauer, A., & Sacks,B. (2015).  The Effect of Genetic Bottlenecks and Inbreeding on the Incidence of Two Major Autoimmune Diseases in Standard Poodles, Sebaceous Adenitis and Addison's Disease.  Canine Genetics and Epidemiology, 2:14. (DOI:10.1186/s40575-015-0026-5)
  • Truve, K., Dickinson, P., Xiong, A., York, D., Jayashankar, K., Pielberg, G., et al. (2016). Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development - Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus. Public LIbrary of Science Genetics, e1006000. (DOI: 10.1371/journal.pgen.1006000)
  • Safra, N., Bassuk, A.G., Ferguson, P.J., Aguilar, M., Coulson, R.L., Thomas, N., Hitchens, P.L., Dickinson, P.J., Vernau, K.M., Wolf, Z.T., Bannasch, D.L. (2013). Genome-Wide Association Mapping in Dogs Enables Identification of the Homeobox Gene, NKX2-8, as a Genetic Component of Neural Tube Defects in Humans. Public Library of Science One Genetics, 9(7): e1003646. (DOI:10.1371/journal.pgen.1003646)
  • Vernau, K., Runstadler, J.A., Brown, E.A., Cameron, J.M., Juson, H.J., Higgins, R.J., Ackerley, C., Sturges, B.K., Dickinson, P.J., Purschner, B., Giulivi, C., Shelton, D., Robinson, B.H., DiMauro, S., Bollen, A.W., & Bannasch, D. (2013). Genome-Wide Association Analysis Identifies a Mutation in the Thiamine Transporter 2 (SLC19A3) Gene Associated with Alaskan Husky Encephalopathy. Public Library of Science One, 8(3): e57195. (DOI:10.1371/journal.pone.0057195)
Oncology (Cancer)
  • Burton, J., & Khanna, C. (2014). The Role of Clinical Trials in Veterinary Oncology. Veterinary Clinics of North America: Small Animal Practice, 44(5): 977-87.  (DOI:
  • Frazier, S.A., McKemie, D.S., Guerrero, T.A., Lachapelle, H., Skorupski, K.A., Kass, P.H., & Rodriguez, Jr., C.O. (2012). Phase I clinical trial of oral rosiglitazone in combination with intraveous carboplatin in cancer-bearing dogs.  Veterinary and Comparative Oncology, ePub 24 Feb 2012.  (DOI: 10.1111/j.1476-5829.2012.00322.x)
Ophthalmology (Eyes)
  • Labelle, A.L., Hamor, R.E., Townsend, W.M., Mitchelle, M.A., Zarfoss, M.K., Breaux, C.B., Thomasy, S.M., & Hall, T. (2011). Ophthalmic lesions in neonatal foals evaluated for nonophthalmic disease at referral hospitals. Journal of the American Veterinary Medical Association, 239 (4), 486-92. (DOI:10.2460/javma.239.4.486)
  • Thomasy, S.M., Covert, J.C., Stanley, S.D., & Maggs, D.J. (2012). Pharmacokinetics of famciclovir and penciclovir in tears following oral administration of famciclovir to cats: a pilot study. Veterinary Ophthalmology, 1-8. (DOI:10.1111/j.1463-5224.2011.00984.x)