Success Stories

Photo: Case of the Month November 2016 - Fred the Dog

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VMTH Clinical Trial "Case of the Month" for November 2016

Fred, a 6-year-old male shepherd cross, was diagnosed by his referring veterinarian with cancer in his left forelimb in April 2016. Due to preexisting orthopedic issues, he was not a candidate for the traditional amputation and chemotherapy treatment. Faced with only being offered palliative care for Fred, his dedicated owners, Rob and Linda, continued to hope and sought out other options. They discovered a new clinical trial at the UC Davis veterinary hospital that offered a cutting-edge approach to treating dogs with osteosarcoma.

Read Fred's full story

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Anesthesia & Pain Management

Hulahalla the Thoroughbred gets a new lease on life with experimental treatment for Laminitis

After a tendon injury, Hulahalla retired from a career in racing and became part of the teaching/research herd of the UC Davis Center for Equine Health. For unknown reasons, she developed laminitis, a devastating inflammatory condition that affects the nailbed, causing severe pain and suffering. Many of these cases are unresponsive or poorly responsive to current standard of care practices. As a consequence, many horses are put down as a last resort to end the pain and agony. Famous horses that lost their lives as a consequence of laminitis include Secretariat, the 1973 US Triple Crown champion, and more recently, Barbaro, the 2006 Kentucky Derby winner. Countless other horses lose their lives to laminitis. Instead of subjecting Hulahalla to Secretariat's or Barbaro's fate, Assistant Professor of Clinical Surgical and Radiological Sciences, Dr. Alonso Guedes, administered an experimental compound, t-TUCB, to Hulahalla, who at this point was not responding to the standard of care, was lying down for most of the time, and had extremely high blood pressure and pain. After only four days of treatment, the veterinarians saw great improvements in her demeanor, blood pressure, and pain levels. Hulahalla had a complete recovery and, as of 2013, has been laminitis-free!


  • Guedes, A.G.P., Morisseau, C., Sole, A., Soares, J.H.N., Ulu, A., Dong, H., & Hammock, B.D. (2013). "Use of a soluable epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis".  Veterinary Anaesthesia and Analgesia, ePub 7 Mar 2013. DOI: 10.1111/vaa.12030