Googgie, a 17-week-old spayed female Sphynx, was brought to the UC Davis veterinary hospital following a three-day bout of inappetence, lethargy and vomiting. Originally seen by the Emergency and Critical Care Service, she was noted to have an enlarged, painful left kidney.With ultrasound, it was discovered that an obstruction of the left ureter was preventing flow of urine to the bladder. It could not be determined through imaging what was causing the blockage, and surgery was needed to discover, then alleviate, the obstruction.
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Anesthesia & Pain Management
After a tendon injury, Hulahalla retired from a career in racing and became part of the teaching/research herd of the UC Davis Center for Equine Health. For unknown reasons, she developed laminitis, a devastating inflammatory condition that affects the nailbed, causing severe pain and suffering. Many of these cases are unresponsive or poorly responsive to current standard of care practices. As a consequence, many horses are put down as a last resort to end the pain and agony. Famous horses that lost their lives as a consequence of laminitis include Secretariat, the 1973 US Triple Crown champion, and more recently, Barbaro, the 2006 Kentucky Derby winner. Countless other horses lose their lives to laminitis. Instead of subjecting Hulahalla to Secretariat's or Barbaro's fate, Assistant Professor of Clinical Surgical and Radiological Sciences, Dr. Alonso Guedes, administered an experimental compound, t-TUCB, to Hulahalla, who at this point was not responding to the standard of care, was lying down for most of the time, and had extremely high blood pressure and pain. After only four days of treatment, the veterinarians saw great improvements in her demeanor, blood pressure, and pain levels. Hulahalla had a complete recovery and has been laminitis-free for the past year and a half!
A clinical trial to further examine this experimental anti-inflammatory compound is awaiting funding.
- Guedes, A.G.P., Morisseau, C., Sole, A., Soares, J.H.N., Ulu, A., Dong, H., & Hammock, B.D. (2013). "Use of a soluable epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis". Veterinary Anaesthesia and Analgesia, ePub 7 Mar 2013. DOI: 10.1111/vaa.12030