Progressive retinal degeneration

Source dog, 5 year spayed female golden retriever, OD (UC Davis Clinic 183575, Pathol 79N1734, Ophthal 79071)
Fixative glutaraldehyde, osmium
Stain azure II-methylene blue
Notes ventral to optic disk; shows essentially total loss of outer layers and substantial loss of inner layers; notice clumping of retinal epithelial cells which corresponds to hypermelanotic zones in the fundus
See also ocular fundus corresponding to this region
dorsolateral to edge of optic disk
Legend integral to image
Illustration click on image to see larger picture