Retinal epithelial dystrophy (central progressive retinal degeneration)

Source dog
Fixative formalin?
Stain hematoxylin & eosin
Notes retinal epithelial cells are enlarged due to accumulation of lipofuscin which is fluorescent
See also another H&E section
another H&E section
another H&E section
fluorescence microscopy section
Legend c - choroid; r - retinal epithelium: most of cytoplasm of these enlarged cells filled with light brown pigment which is lipofuscin; sometimes large lysosomal bodies are seen (arrow)
Illustration click on image to see larger picture