Abnormal retinal blood vessels in diabetes mellitus, trypsin digest

Source dog, 12 year male springer spaniel
Fixative formalin
Stain periodic acid-Schiff, hematoxylin
Notes this dog had diabetes mellitus from many years; notice the substantial loss of pericyte and endothelial cell nuclei
See also similar field in normal retina
similar field in normal retina
Legend integral to image
Illustration click on image to see larger picture