Optic nerve degeneration in glaucoma, cross section

Source 2.5 year male Doberman pinscher, OS
Fixative Zenker's
Stain Luxol fast blue
Notes This eye had glaucoma and panophthalmitis due to blastomycosis; this image shows early optic nerve degeneration (notice the reduction in stained myelinated nerve fibers compared with the nerve from the normal eye)
See also normal, Luxol fast blue
Legend arrow - points to extensions of pia mater which form the septae (along with astrocytes) that surround each fascicle, A - arachnoid, F - fascicle
Illustration Click on image to see larger picture