Laura Van Winkle- BS, PhD
+1 530 754 7547
The role of sex-differences and xenobiotic metabolism in lung pathology and toxicology. Air pollution including tobacco smoke, particulates and ozone. Growth factors and cell-cell interactions in lung wound healing, in lung disease (lung cancer and asthma) and during lung development. Cell proliferation and progenitor cells. Microscopes and imaging methods.
Toxicology of the lung. Diplomate American Board of Toxicology (DABT)
1987 BS Pharmacology, University of California, Santa Barbara
Honors and Awards
1992-1993 Graduate Fellowship in Environmental Health Sciences
Diplomate American Board of Toxicology (General Toxicology)
Active Research Grants
Principal Investigator, San Joaquin Health Effects Research Center Project 1: Pulmonary metabolic response, Dr. Wexler is the PI on the entire $8 million Project. Dr. Van Winkle's Project #1 is funded in the amount of $1,285,200 (Principal Investigator), US EPA
Principal Investigator, Engineered Nanomaterials: Linking Physical and Chemical Properties to Biology, Pinkerton/Van Winkle (Principal Investigator), NIH/NIEHS
Co-Investigator, Novel approaches to evaluate carbon nanotube health impacts, Pinkerton (Principal Investigator), NIH/NIEHS
Principal Investigator, Comparative kinetics of metabolism of naphthalene in nasal epithelial microsomes from the mouse and monkey, Buckpitt/Van Winkle (Principal Investigator), American Petroleum Institute (API)
Co-Investigator, Health Effects of Central Valley Particulate Matter, Wexler (Principal Investigator), California Air Resources Board
Co-Investigator, Superfund Basic Research Program - Biomarkers to Hazardous Chemicals: Project 4: Urinary Protein Biomarkers for assessing the potential for toxicity, Hammock PI of P42/Buckpitt PI of Project 4 (Principal Investigator), NIH/NIEHS
Co-Investigator, Pulmonary Effects of Environmental Oxidant Pollutants - Project 3: Innervation & Neural Control, Hyde PI of P01/Schelegle PI of Project 3 (Principal Investigator), NIH/NIEHS
Most Recent 10 Publications
Most Recent 5 Book Chapters
2010 Pinkerton KE, Smiley-Jewell S, Van Winkle LS: Tracheobronchial airways, Yost et al, (ed), Toxicology of the Respiratory System, Comprehensive Toxicology, 2nd Edition. .
2010 Van Winkle LS: Cell damage and cell renewal in the lung, Yost et al, (ed), Toxicology of the Respiratory System, Comprehensive Toxicology, 2nd Edition. .
2008 Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM: Primate Models of Allergic Asthma, Kay AB et al, (ed), Allergy and Allergic Diseases, London. Chapter 54.
2008 Hyde DM, Miller LA, Schelegle ES, Fanucchi MV, Van Winkle LS, Tyler NK, Avdolovic MV, Evans MJ, Kajekar R, Buckpitt AR, Pinkerton KE, Joad JP, Gershwin LJ, Wu R, Plopper CG: Chronic airway disease in nonhuman primates, Voelkel & MacVee, (ed), Chronic Obstructive Lung Disease. Chapter 17.
2006 Witschi HR, Pinkerton KE, Van Winkle LS, Last JA: Chapter 15: Toxic Responses of the Respiratory System, Klaassen, (ed), Casarett and Doull's Toxicology: the basic science of poisons. .