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Edward Schelegle- BS, MS, PhD
Professor in Residence
Anatomy, Physiology & Cell Biology

2023 VM3B
Davis, CA 95616

+1 530 752 1177
esschelegle@ucdavis.edu

   

Education

1976 BS Animal Physiology, University of California, Davis, CA
1981 MS Exercise Physiology, University of California, Davis, CA
1988 PhD Cardiorespiratory Physiology & Environmental Toxicology, University of California, Davis, CA

Honors and Awards

1990-1992 Tobacco Related Disease Research Program Postdoctoral Fellowship, Department of Human Physiology, UC Davis
1988-1990 National Institute Health Postdoctoral Traineeship, Department of Internal Medicine, UC Davis
1979 Graduate Research Award, Department of Physical Education, UC Davis

Active Research Grants

Co-Investigator, California Regional Primate Research Center base grant, Barry Klein (Principal Investigator), NIH

Co-Investigator, Biomarkers of pulmonary arterial hypertension, Roblee Allen (Principal Investigator), Gilead, Inc

Principal Investigator, Persistent Immune Effects of Wildfire PM Exposure During Childhood Development, Lisa Miller (Principal Investigator), California Air Resources Board

Most Recent 10 Publications

  • Edward Schelegle: Exhaled volatile organic compounds in individuals with a history of high altitude pulmonary edema and varying hypoxia-induced responses. 2015 Figueroa JA, Mansoor JK, Allen RP, Davis CE, Walby WF, Aksenov AA, Zhao W, Lewis WR, Schelegle ES Exhaled volatile organic compounds in individuals with a history of high altitude pulmonary edema and varying hypoxia-induced responses. Journal of Breath Research,
  • Edward Schelegle: Early life exposure to allergen and ozone results in altered development in adolescent rhesus macaque lungs. 2015 Herring MJ, Putney LF, St George JA, Avdalovic MV, Schelegle ES, Miller LA, Hyde DM Early life exposure to allergen and ozone results in altered development in adolescent rhesus macaque lungs. Toxicology and Applied Pharmacology,
  • Edward Schelegle: SMAD Signaling in the Airways of Healthy Versus Asthmatic Rhesus Macaques Highlights a Relationship Between Inflammation and BMPs. 2015 Lynn TM, Molloy EL, Masterson JC, Glynn SF, Costello RW, Avdalovic MV, Schelegle ES, Miller LA, Hyde DM, O'Dea S SMAD Signaling in the Airways of Healthy Versus Asthmatic Rhesus Macaques Highlights a Relationship Between Inflammation and BMPs. American journal of respiratory cell and molecular biology,
  • Edward Schelegle: Diverse forms of pulmonary hypertension remodel the arterial tree to a high shear phenotype. 2014 Allen RP, Schelegle ES, Bennett SH Diverse forms of pulmonary hypertension remodel the arterial tree to a high shear phenotype. American Journal of Physiology. Heart and Circulatory Physiology,
  • Edward Schelegle: Analysis of volatile compounds in exhaled breath condensate in patients with severe pulmonary arterial hypertension. 2014 Mansoor JK, Schelegle ES, Davis CE, Walby WF, Zhao W, Aksenov AA, Pasamontes A, Figueroa J, Allen R Analysis of volatile compounds in exhaled breath condensate in patients with severe pulmonary arterial hypertension. PloS one,
  • Edward Schelegle: Persistence of serotonergic enhancement of airway response in a model of childhood asthma. 2014 Moore BD, Hyde DM, Miller LA, Wong EM, Schelegle ES Persistence of serotonergic enhancement of airway response in a model of childhood asthma. American Journal of Respiratory Cell and Molecular Biology,
  • Edward Schelegle: Ozone-induced airway epithelial cell death, the neurokinin-1 receptor pathway, and the postnatal developing lung. 2014 Murphy SR, Oslund KL, Hyde DM, Miller LA, Van Winkle LS, Schelegle ES Ozone-induced airway epithelial cell death, the neurokinin-1 receptor pathway, and the postnatal developing lung. American Journal of Physiology. Lung Cellular and Molecular Physiology,
  • Edward Schelegle: Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy. 2013 Davis BB, Zeki AA, Bratt JM, Wang L, Filosto S, Walby WF, Kenyon NJ, Goldkorn T, Schelegle ES, Pinkerton KE Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy. Eur Respir J,
  • Edward Schelegle: Behavioral inhibition in rhesus monkeys (Macaca mulatta) is related to the airways response, but not immune measures, commonly associated with asthma 2013 Chun K, Miller LA, Schelegle ES, Hyde DM, Capitanio JP Behavioral inhibition in rhesus monkeys (Macaca mulatta) is related to the airways response, but not immune measures, commonly associated with asthma PloS one,
  • Edward Schelegle: Ozone exposure alters serotonin and serotonin receptor expression in the developing lung. 2013 Murphy SR, Schelegle ES, Miller LA, Hyde DM, Van Winkle LS Ozone exposure alters serotonin and serotonin receptor expression in the developing lung. Toxicol Sci,

Most Recent 5 Book Chapters

2015 Last JA, Pinkerton K, Schelegle ES: Ozone and Oxidant Toxicity, , Reference Module in Biomedical Sciences 2015, New York, New York. .

2009 Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic MV, Gershwin LJ, Joad JP, Kajekar R, Larson SD, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM: Primate Models of Allergic Asthma, Kay AB, Kaplan AP, Bousquet J, Holt PG, (ed), Allergy and Allergic Diseases, Oxford, UK. Chapter 54.

2008 Hyde DM, Miller LA, Schelegle ES, Fanucchi MV, Van Winkle LS, Tyler NK, Avdalovic MV, Evans MJ, Kajekar R, Buckpitt AR, Pinkerton KKE, Joaj JP, Gershwin LJ, Wu R, Plopper CG: Chronic Airway Disease in Nonhuman Primates, NF Voelkel, W MacNee, (ed), Chronic Obstructive Lung Diseases, Hamilton. 235-268.

2001 Plopper CG, Paige R, Schelegle ES, Buckpitt A, Wong V, Tarkington B, Putney L, Hyde DM: Time-response profiles: Implications for injury, repair, and adaptation to ozone, Relationships Between Acute and Chronic Effects of Air Pollution, (ed), U. Heinrich and U. Mohr, Washington, DC. 23-37.

2000 Folinsbee LJ, Schelegle ES: Air pollutants and endurance performance, RJ Shephard and PO Astrand, (ed), Encyclopaedia of Sports Medicine, Endurance in Sports, 2nd Edition, Oxford, UK. 628-38.