Search for Faculty

Photo: Stephen Barthold

Stephen Barthold- BS, DVM, MS, PhD
Professor Emeritus
Pathology, Microbiology & Immunology


Research Focus


Specialty Focus

Anatomic Pathology


1967 BS , University of California, Davis,
1969 DVM , University of California, Davis,
1973 MS , University of Wisconsin, Madison,
1974 PhD , University of Wisconsin, Madison,

Honors and Awards

2008 Pfizer Animal Health Award for Research Excellence
2008 Charles River Prize, American Veterinary Medical Association
2006 Honorary title, Distinguished Professor, UCD
2004 Frank Schofield Medalist, Ontario Veterinary College
2003 Honorary Diplomate, American College of Laboratory Animal Medicine
2001 Oscar W. Schalm Lecturer, University of California Davis School of Veterinary Medicine
2001 Wallace P. Rowe Lecturer, American Association for Laboratory Animal Science
2001 Elected Member, Institute of Medicine, National Academies
1998 Alumni Acheivement Award, University of California School of Veterinary Medicine
1996 Nathan R. Brrewer Award for Career Excellence in Research, American Association for Laboratory Animal Science
1994 American Association for Laboratory Animal Science Research Award
1991 American Association for Laboratory Animal Science Research Award
1978 American Association for Laboratory Animal Science Research Award


Diplomate American College of Veterinary Pathologists
State Licensure - California

Active Research Grants

Principal Investigator, Mouse Model of Lyme Borreliosis, (Principal Investigator), NIH/NIAID

Principal Investigator, Humoral Responses to Lyme Borreliosis-A Mouse MOdel, (Principal Investigator), NIH

Co-Investigator, Mutant Mouse Regional Resource Center, Lloyd (Principal Investigator), NIH

Principal Investigator, Comparative Medical Science Training Program, (Principal Investigator), NIH

Most Recent 10 Publications

  • Link Icon 2011 Bolon B, Altrock B, Barthold SW, Baumgarth N, Besselsen D, Boivin G, Boyd KL, Brayton C, Cardiff RD, Couto S, Eaton KA, Foreman O, Griffey SM, La Perle K, Lairmore MD, Liu C, Meyerholz DK, Nikitin AY, Schoeb TR, Schwahn D, Sellers RS, Sundberg JP, Tolwani R, Valli VE, Zink MC Advancing translational research Science,
  • Link Icon 2011 Imai DMBarr BCDaft BBertone JJFeng SHodzic EJohnston JMOlsen KJBarthold SW Lyme Neuroborreliosis in 2 Horses Vet Pathol,
  • Link Icon 2010 Blanchard MT, Chen CI, Anderson M, Hall MR, Barthold SW, Stott JL Serial passage of the etiologic agent of epizootic bovine abortion in immunodeficient mice Vet Microbiol,
  • Link Icon 2009 Feng S, Kasten RW, Werner JA, Hodzic E, Barthold SW, Chomel BB Immunogenicity of Bartonella henselae P26 in cats Vet Immunol Immunopathol,
  • Link Icon 2009 Barthold SW, Hodzic E, Imai DM, Feng S, Yang X, Luft BJ Ineffectiveness of tigecycline against persistent Borrelia burgdorferi Antimicrob Agents Chemother,
  • Link Icon 2008 Hodzic E, Feng S, Holden K, Freet KJ, Barthold SW Persistence of Borrelia burgdorferi following antibiotic treatment in mice Antimicrob Agents Chemother,
  • Link Icon 2008 Werner JA, Feng S, Chomel BB, Hodzic E, Kasten RW, Barthold SW P26-based serodiagnosis for Bartonella spp. infection in cats Comp Med,
  • Link Icon 2007 Hovius JW, Li X, Ramamoorthi N, van Dam AP, Barthold SW, van der Poll T, Speelman P, Fikrig E Coinfection with Borrelia burgdorferi sensu stricto and Borrelia garinii alters the course of murine Lyme borreliosis FEMS Immunol Med Microbiol,
  • Link Icon 2007 Strother KO, Hodzic E, Barthold SW, de Silva AM Infection of mice with lyme disease spirochetes constitutively producing outer surface proteins A and B Infect Immun,
  • Link Icon 2007 Werner JA, Kasten RW, Feng S, Sykes JE, Hodzic E, Salemi MR, Barthold SW, Chomel BB Experimental infection of domestic cats with passaged genotype I Bartonella henselae Vet Microbiol,

Most Recent 5 Book Chapters

2010 Barthold SW: Laboratory Animal Viruses, MacLachlan NJ, Dubovi EJ, (ed), Fenner's Veterinary Virology, Fourth Edition. .

2010 Barthold SW, Cadavid D, Philipp M: Animal Models of Borreliosis, S. Samuels and J Radolph, (ed), Borrelia: Molecular Biology, Host Interaction and Pathogenesis, Norfolk, UK. .

2009 Barthold SW, Bolser D, Garcia KD, Haywood JR, Leland S, Miller L, Nelson RJ, Serpell J, Talcott MR, Whitney R: Scientific and Humane Issues in the Use of Random-Source Dogs and Cats in Research, , National Research Council, Washington DC. .

2007 Barthold SW, and Smith AL: Lymphocytic Choriomeningitis Virus, Fox JG et al, (ed), The Mouse in Biomedical Research: Diseases, San Diego. .

2007 Barthold SW and Smith AL: Mouse Hepatitis Virus, Fox JG, et al, (ed), The Mouse in Biomedical Research: Diseases Vol. II, San Diego, CA. .