Search for Faculty

Photo: N. James MacLachlan

N. James MacLachlan- BVSc, MS, PhD
Professor
Pathology, Microbiology & Immunology

5325 Vet Med 3A
Davis, CA 95616

+1 530 754 8125
njmaclachlan@ucdavis.edu

   

Research Focus

I study viral diseases of livestock that impact international commerce, notably emerging diseases such as bluetongue and African horse sickness that are transmitted by Culicoides biting midges. These diseases and their vectors are poorly characterized and are of increasing global concern, thus I serve regularly as an expert advisor to numerous organizations including the World Organization for Animal Health (O.I.E), the United States Departments of Agriculture and Homeland Security, and the European Union. My research laboratory is productively engaged in studying these diseases both locally and internationally and, in the process, training research scientists (including veterinarians) for careers in academia, industry and government.

Specialty Focus

Anatomic Pathology

Education

1975 BVSc Veterinary Medicine, Massey University, New Zealand
1979 MS Virology, University of Missouri, Columbia
1982 PhD Comparative Pathology, University of California, Davis,

Honors and Awards

2012 Sir Arnold Theiler Memorial Lecture, University of Pretoria, South Africa
2008, 2010 Keynote speaker, Senior Banquet, Veterinary School Classes of 2008 and 2010
2008 Recombinant vaccine against bluetongue virus, Patent WO/2008/030282; granted March 13, 2008: N James MacLachlan one of four listed inventors. http://www.wipo.int/pctdb/en/wo/jsp?wo=2008030282
2008 Recombinant African horse sickness vaccine, US Provisional application number 61/108,075 filed October 24, 2008. N. J. MacLachlan one of five listed investors. http://www.faqs.org/patents/app/20100119546
2007-2015 Appointed Extraordinary Professor, Department of Tropical Veterinary Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
2007 Alumni Achievement Award, School of Veterinary Medicine, University of California, Davis
2007 Invited Visiting Scientist, Institute of Virology and Immunoprophylaxis, Mittlehausern, Switzerland
2003 Pfizer Animal Health Award for Research Excellence, School of Veterinary Medicine, University of California
1998 President, American College of Veterinary Pathologists
1994 Commencement speaker, School of Veterinary Medicine, University of California
1993-2010 Outstanding/Favorite Teacher Award, Sophomore year 1993, 2003, 2006, 2008; UC Davis Veterinary Classes of 1995, 2005, 2008 and 2010
1993 Norden Distinguished Teaching Award, School of Veterinary Medicine, University of California

Licenses

Diplomate American College of Veterinary Pathologists

Active Research Grants

Principal Investigator, Bernard and Gloria Salick Equine Viral Disease Laboratory, (Principal Investigator), Salick Foundation

Principal Investigator, Characterization of the ecological drivers of bluetongue virus (BTV) infection of livestock for the predictive modeling of an emerging, economically important arboviral disease, (Principal Investigator), National Institute of Food and Agriculture

Principal Investigator, Bluetongue virus infection of ruminants in California: Pathogenesis and epizootiology, (Principal Investigator), Center for Food Animal Health

Principal Investigator, Research: $15,556, Principal Investigator, Host-virus interactions in bluetongue virus-infected ruminants, (Principal Investigator), USDA Formula Funds

Principal Investigator, Epizootic Hemorragic Disease (EHD): Epidemiology and Development of Vacine for White-tailed deer (Odocoileus Virginianus), (Principal Investigator), Kansas State University

Most Recent 10 Publications

  • N. James MacLachlan: Complete genome sequences of four African horse sickness virus strains from a commercial tetravalent live attenuated vaccine 2015 Guthrie AJ, Coetzee P, Martin DP, Lourens CW, Venter EH, Weyer CT, Joone C, le Grande M, Harper CK, Howell PG, Maclachlan NJ Complete genome sequences of four African horse sickness virus strains from a commercial tetravalent live attenuated vaccine Genome Announcments,
  • N. James MacLachlan: Complete genome sequences of the three African horse sickness virus strains from a commercial trivalent live attenuated vaccine 2015 Guthrie AJ, Coetzee P, Martin DP, Lourens CW, Venter EH, Weyer CT, Joone C, le Grande M, Harper CK, Howell PG, Maclachlan NJ Complete genome sequences of the three African horse sickness virus strains from a commercial trivalent live attenuated vaccine Genome Announcements,
  • N. James MacLachlan: Bluetongue virus infection creates light averse Culicoides vectors and serious errors in transmission risk estimates 2015 McDermott EG, Mayo CE, Gerry AC, Laudier D, Maclachlan NJ, Mullens BA Bluetongue virus infection creates light averse Culicoides vectors and serious errors in transmission risk estimates Parasites and Vectors,
  • N. James MacLachlan: Orbiviruses: A North American perspective 2015 McVey DS, Drolet BS, Ruder MG, Wilson WC, Nayduch D, Pfannesteil R, Cohnstaedt LW, Maclachlan NJ, Gay CG Orbiviruses: A North American perspective Vector Borne Zoonotic Diseases,
  • N. James MacLachlan: Serotype specific real-time reverse transcription PCR assays for detection of reference and field strains of the nine serotypes of African horse sickness virus 2015 Weyer CT, Joone C, Lourens CW, Monyai MS, Koekemoer O, Grewar JD, Majwa P, Maclachlan NJ, Guthrie AJ Serotype specific real-time reverse transcription PCR assays for detection of reference and field strains of the nine serotypes of African horse sickness virus ,
  • N. James MacLachlan: Vaccines for prevention of bluetongue and epizootic hemorrhagic disease in livestock – a North American perspective 2015 McVey DS, Maclachlan NJ. Vaccines for prevention of bluetongue and epizootic hemorrhagic disease in livestock – a North American perspective Vectorborne and Zoonotic Diseases,
  • N. James MacLachlan: The Changing Global Face of Bluetongue:  From the Beginning 2015 Maclachlan NJ The Changing Global Face of Bluetongue: From the Beginning Veterinaria Italiana,
  • N. James MacLachlan: Lack of evidence of laboratory and natural vertical transmission of bluetongue virus in Culicoides sonorensis (Diptera: Ceratopogonidae) 2015 Osborne CJ, Mayo CE, Mullens BA, McDermott EG, Gerry AC, Reisen WK, Maclachlan NJ Lack of evidence of laboratory and natural vertical transmission of bluetongue virus in Culicoides sonorensis (Diptera: Ceratopogonidae) Journal of Medical Entomology,
  • N. James MacLachlan: Epizootic haemorrhagic disease 2015 Maclachlan NJ, Zientara S, Savini G, Daniels PW. Epizootic haemorrhagic disease OIE Scientific and Technical Review,
  • N. James MacLachlan: Bluetongue 2015 Maclachlan NJ, Mayo CE, Daniels PW, Zientara S, Savini G, Gibbs EP. Bluetongue OIE Scientific and Technical Review,

Most Recent 5 Book Chapters

2014 Maclachlan NJ, Mayo CE: Bluetongue, Smith BP, (ed), Large Animal Internal Medicine, 5th edition. 745-747.

2013 Balasuriya UBR, MacLachlan NJ: Equine viral arteritis, Sellon DC, Long MT, (ed), Equine Infectious Diseases. .

2010 MacLachlan NJ, Dubovi EJ: BOOK: Fenner's Veterinary Virology, Fourth Edition, MacLachlan & Dubovi, (ed), . .

2008 MacLachlan NJ: Bluetongue, Brown CC, Torres A, (ed), Foreign Animal Diseases "The Gray Book.". 159-165.

2008 MacLachlan NJ, Gard GP: Clinical signs and pathology, in Pastoret, Mertens PP, Baylis M, Mellor P, (ed), Bluetongue. 285-293.