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Photo: N. James MacLachlan

N. James MacLachlan- BVSc, MS, PhD
Pathology, Microbiology & Immunology

5325 Vet Med 3A
Davis, CA 95616

+1 530 754 8125


Research Focus


Specialty Focus

Anatomic Pathology


1975 BVSc Veterinary Medicine, Massey University, New Zealand
1979 MS Virology, University of Missouri, Columbia
1982 PhD Comparative Pathology, University of California, Davis,

Honors and Awards

2012 Sir Arnold Theiler Memorial Lecture, University of Pretoria, South Africa
2008, 2010 Keynote speaker, Senior Banquet, Veterinary School Classes of 2008 and 2010
2008 Recombinant vaccine against bluetongue virus, Patent WO/2008/030282; granted March 13, 2008: N James MacLachlan one of four listed inventors.
2008 Recombinant African horse sickness vaccine, US Provisional application number 61/108,075 filed October 24, 2008. N. J. MacLachlan one of five listed investors.
2007-2015 Appointed Extraordinary Professor, Department of Tropical Veterinary Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
2007 Alumni Achievement Award, School of Veterinary Medicine, University of California, Davis
2007 Invited Visiting Scientist, Institute of Virology and Immunoprophylaxis, Mittlehausern, Switzerland
2003 Pfizer Animal Health Award for Research Excellence, School of Veterinary Medicine, University of California
1998 President, American College of Veterinary Pathologists
1994 Commencement speaker, School of Veterinary Medicine, University of California
1993-2010 Outstanding/Favorite Teacher Award, Sophomore year 1993, 2003, 2006, 2008; UC Davis Veterinary Classes of 1995, 2005, 2008 and 2010
1993 Norden Distinguished Teaching Award, School of Veterinary Medicine, University of California


Diplomate American College of Veterinary Pathologists

Active Research Grants

Principal Investigator, Bernard and Gloria Salick Equine Viral Disease Laboratory, (Principal Investigator), Salick Foundation

Principal Investigator, Characterization of the ecological drivers of bluetongue virus (BTV) infection of livestock for the predictive modeling of an emerging, economically important arboviral disease, (Principal Investigator), National Institute of Food and Agriculture

Principal Investigator, Bluetongue virus infection of ruminants in California: Pathogenesis and epizootiology, (Principal Investigator),

Most Recent 10 Publications

  • Link Icon 2013 Weyer, C.T., Quan, M., Joone, C., Lourens, C.W., Maclachlan, N.J., Guthrie, A.J. African horse sickness in naturally infected, imunised horses Equine Veterinary Journal,
  • Link Icon 2012 Mayo CE, Barker CM, Mullens BA, Gerry AC, Mertens PP, Maan S, Maan N, Gardner IA, Guthrie AJ, Maclachlan NJ The combination of abundance and infection rates of Culicoides sonorensis estimates risk of subsequent bluetongue virus infection of sentinel cattle on California dairy farms Veterinary Parasitology,
  • Link Icon 2012 Mayo CE, Gardner IA, Mullens BA, Barker CM, Gerry AC, Guthrie AJ, Maclachlan NJ Anthropogenic and metereological factors influence vector abundance and the prevalence of bluetongue virus infection of dairy cattle in California Veterinary Microbiology,
  • Link Icon 2012 Schefffer EG, Venter GJ, Labuschagne K, Page PC, Mullens BA, Maclachlan NJ, Osterrieder N, Guthrie AJ Comparison of two trapping methods for Culicoides biting midges and determination of African horse sickness virus prevalence in midge populations at Onderstepoort, South Africa Veterinary Parasitology,
  • Link Icon 2011 Brault SA, Maclachlan NJ Equid gammaherpesviruses: Persistent bystanders or true pathogens Veterinary Journal,
  • Link Icon 2011 Maclachlan NJ Bluetongue: History, global epidemiology, and pathogenesis Preventive Veterinary Medicine,
  • Link Icon 2011 Brault SA, Bird BH, Balasuriya UB, Maclachlan NJ Genetic heterogeneity and variation in viral load during equid herpesvirus-2 infection of foals Veterinary Microbiology,
  • Link Icon 2010 Gohrman J, Gabriel M, Maclachlan NJ, Nieto N, Foley J, Spier S Pilot immunization of mice infected with an equine strain of Corynebacterium pseudotuberculosis Veterinary Therapeutics,
  • Link Icon 2010 Drew CP, Gardner IA, Mayo CE, Matsuo E, Roy P, MacLachlan NJ Bluetongue virus infection alters the impedance of monolayers of bovine endothelial cells as a result of cell death Veterinary Immunology Immunopathology,
  • Link Icon 2010 Quan M, Lourens CW, Maclachlan NJ, Gardner IA, Guthrie AJ Development and optimisation of a duplex real-time reverse transcription quantitative PCR assay targeting the VP7 and NS2 genes of African horse sickness virus Journal of Virological Methods,

Most Recent 5 Book Chapters

2010 MacLachlan NJ, Dubovi EJ: BOOK: Fenner's Veterinary Virology, Fourth Edition, MacLachlan & Dubovi, (ed), . .

2008 MacLachlan NJ, Balasuriya UB, Murtaugh MP, Barthold SW, Lowenstine LJ: Arterivirus pathogenesis and immune response, Perlman S, Gallagher T, Snijder E, (ed), The Nidoviruses. 325-337.

2008 MacLachlan NJ: Bluetongue, Brown CC, Torres A, (ed), Foreign Animal Diseases "The Gray Book.". 159-165.

2008 MacLachlan NJ, Gard GP: Clinical signs and pathology, in Pastoret, Mertens PP, Baylis M, Mellor P, (ed), Bluetongue. 285-293.

2006 Balasuriya UB, MacLachlan NJ: Equine viral arteritis, Sellon D, Long M, (ed), Infectious Diseases of the Horse, St. Louis. 153-164.