UC Davis School of Veterinary Medicine: Faculty Results

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	Leslie Lyons- BS, MS, PhD Professor Population Health & Reproduction 260 CCAH Davis, CA 95616 +1 530 754 5546 lalyons@ucdavis.edu

Specialty Focus	Genetics
Education	1996 Post-Doctoral Fellow Feline Genetics, Laboratory of Viral Carcinogenesis, National Cancer Institute, Frederick, MD 1992 Post-Doctoral Fellow Human Genetics, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 1991 PhD Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 1987 MS Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 1985 BS Biochemistry, University of Pittsburgh, College of Arts and Sciences, Pittsburgh, PA
Honors and Awards	1982 Phi Eta Sigma, University of Pittsburgh 1987-1991 Graduate Student Representative, GSPH 1990-1991 Doctoral Student Organization, GSPH 2001 Undergraduate mentoring award, nominated 2007 Chancellor's Research Award, nominated 2008 Chancellor's Research Award, nominated 2010 AVMF / Winn Feline Foundation Research Award
Licenses	Short Course on Medical and Experimental Mammalian Genetics, Jackson Laboratory, Bar Harbor, ME July (2 weeks) Feline Genetics and Health for Cat Breeders, Cornell University American Association of Laboratory Animal Science (AALAS) Laboratory Animal Technician Advanced Linkage Analysis, Columbia University
Active Research Grants	Principal Investigator, Development of Viable Tissue Cultures for Californian Bats (Order Chiroptera), Project No. 2000147, (Principal Investigator), Genetic Resources Conservation Program Co-Investigator, Analysis of Genes Influencing PKD Progression in Cats, Robert Grahn (Principal Investigator), UCD: VM: Center for Companion Animal Health Principal Investigator, Genetic Mapping Resources for Common Mammalian Diseases, (Principal Investigator), NIH: National Center Research Resources Principal Investigator, Mammalian Models for Human Disease, (Principal Investigator), UC Davis CCAH Match NIH R24 Co-Investigator, Health Concerns of Dominant Traits in Domestic Cats, Robert Grahn (Principal Investigator), Winn Feline Foundation Principal Investigator, Genetic Components Influencing the Feline – Human Social Bond, Leslie A. Lyons (Principal Investigator), NIH - NICHD Co-Principal Investigator, Conclusion of the Orange Saga, Robert Grahn (Principal Investigator), UCD: VM: Center for Companion Animal Health Co-Investigator, MITF - The Great White Hope, Barbara Gandolfi (Principal Investigator), UCD: VM: Center for Companion Animal Health Principal Investigator, Genome-wide Association Studies of Brachycephaly in Domestic Cats (96 DNA arrays = $21,600), Leslie Lyons (Principal Investigator), Cat Health Network / Morris Animal Foundation Co-Principal Investigator, Wringing DNA from Stones: Assessing Uroliths for Genetic Studies, (Principal Investigator), UC Davis Center for Companion Animal Health Principal Investigator, CHN - UC Davis CCAH GWAS Match $25.00 per array, Leslie Lyons (Principal Investigator), UC Davis CCAH Principal Investigator, Genetic Estimation of Introgression between Domestic Cat (276 DNA arrays = $62,100) and Wildcat Populations, (Principal Investigator), Cat Health Network / Morris Animal Foundation Co-Principal Investigator, Genome-wide Association Study for Congenital Muscular Dystrophy in Sphynx and Devon Rex cats (60 DNA arrays = $13,500), Robert Grahn (Principal Investigator), Cat Health Network Co-Investigator, Genetic susceptibility to Feline Infectious Peritonitis (FIP), Niels Pedersen (Principal Investigator), Cat Health Network / Morris Animal Foundation Co-Investigator, Osteochondrodysplasia in the Scottish Fold cat breed (200 DNA arrays, $45,000), Bianca Haase (Principal Investigator), Cat Health Network / Morris Animal Foundation Co-Principal Investigator, Identification of the Gene Causing Autosomal Dominant Feline Dwarfism, Robert Grahn (Principal Investigator), UCD VM: Center for Companion Animal Health Principal Investigator, Cat Health Network GWAS in Cats - 4 Projects (408 DNA arrays = $91,800), Leslie Lyons (Principal Investigator), Cat Health Network Principal Investigator, Genome-wide Association Studies (GWAS) for Domestic Cat Diseases and Traits, Leslie Lyons (Principal Investigator), UC Davis VM: Center for Companion Animal Health CHN match $25.00 per array Co-Principal Investigator, Cat Health Network GWAS in Cats (552 DNA arrays = $124,200), Grahn, Gandolfi, Rusbridge (Principal Investigator), Cat Health Network Co-Principal Investigator, Molecular Characterization of Bengal Progressive Retinal Atrophy, Robert Grahn (Principal Investigator), Winn Feline Foundation & CCAH Match $4,221 Co-Principal Investigator, Characterization of the AB blood type in the domestic cat, Gandolfi, Barbara (Principal Investigator), UC Davis CCAH
Most Recent 10 Publications	2012 Bach LH, Gandolfi B, Grahn JC, Millon LV, Kent MS, Narfstrom K, Cole SA, Mullikin JC, Grahn RA, Lyons LA A high-resolution 15,000(rad) radiation hybrid panel for the domestic cat Cytogenet Genome Res, 2012 Grahn RA, Ellis MR, Grahn JC, Lyons LA A novel CYP27B1 mutation causes a feline vitamin D-dependent rickets type IA J Feline Med Surg, 2012 Filler S, Alhaddad H, Gandolfi B, Kurushima JD, Cortes A, Veit C, Lyons LA, Brem G Selkirk Rex: Morphological and Genetic Characterization of a New Cat Breed J Hered, 2012 Lyons LA Genetic testing in domestic cats Mol Cell Probes, 2012 Kurushima JD, Ikram S, Knudsen J, Bleiberg E, Grahn RA, Lyons LA Cats of the Pharaohs: Genetic Comparison of Egyptian Cat Mummies to their Feline Contemporaries Journal of Archeological Sciences, 2011 Grahn RA, Kurushima JD, Billings NC, Grahn JC, Halverson JL, Hammer E, Ho CK, Kun TJ, Levy JK, Lipinski MJ, Mwenda JM, Ozpinar H, Schuster RK, Shoorijeh SJ, Tarditi CR, Waly NE, Wictum EJ, Lyons LA Feline non-repetitive mitochondrial DNA control region database for forensic evidence Forensic Sci Int Genet, 2011 Schlafer DH, Valentine B, Fahnestock G, Froenicke L, Grahn RA, Lyons LA, Meyers-Wallen VN A Case of SRY-Positive 38,XY True Hermaphroditism (XY Sex Reversal) in a Cat Vet Pathol, 2011 Tarditi CR, Grahn RA, Evans JJ, Kurushima JD, Lyons LA Mitochondrial DNA sequencing of cat hair: an informative forensic tool J Forensic Sci, 2010 Gandolfi B, Outerbridge CA, Beresford LG, Myers JA, Pimentel M, Alhaddad H, Grahn JC, Grahn RA, Lyons LA The naked truth: Sphynx and Devon Rex cat breed mutations in KRT71 Mamm Genome, 2010 Karere GM, Lyons LA, Froenicke L Enhancing radiation hybrid mapping through whole genome amplification Hereditas,
Most Recent 5 Book Chapters	2011 Lyons LA: Genetics of Feline Diseases and Traits, Susan Little, (ed), The Cat: Clinical Medicine and Management. . 2011 Lyons LA: The Feline Genome and Clinical Implications, Susan Little, (ed), The Cat: Clinical Medicine and Management. . 2011 Lyons LA, Kurushima JD: A Short Natural History of the Cat and Its Relationship with Humans, Susan Little, (ed), The Cat: Clinical Medicine and Management. . 2009 Bighignoli B, Owens SD, Froenicke F, Lyons LA: Blood types of the domestic cat, August J, (ed), Consultations in Feline Medicine. . 2009 Lyons LA: Genetic testing in domestic cats, August J, (ed), Consultations in Feline Medicine. .