Cecilia Giulivi- MS, PhD
- Biosynthesis and metabolism of nitric oxide in mammalian cells.
- Role of nitric oxide and oxygen free radicals on mitochondria and celll functions.
- Mitochondrial nitrated proteins: role of nitration, metabolism of nitrated proteins, implications for pathophysiology.
- Oxygen and nitrogen free radical biochemistry and chemistry in in vitro and in vivo model systems. Mechanistic aspects of oxygen and nitrogen free radical damage.
- Proteomics of aging and oxidative damage of mitochondria.
- Role of mitochondria in fragile-X, tremor, ataxia syndrome, autism, and Huntington's disease.
Mechanisms of mitochondrial dysfunction in autism, fragile X tremor and ataxia syndrome, Hungton's disease, diabetes and nutrional imbalances as well as in malaria hosts.
1989 PhD Biochemistry, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
Honors and Awards
1985-1987 Fellowship from National Research Council (CONICET) Buenos Aires, Argentina
Active Research Grants
Principal Investigator, Surgical amelioration of type 2 diabetes: hormones, microbiota and mitochondria, Peter Havel(Contact)/Cecilia Giulivi (MPI) (Principal Investigator), NIH
Co-Investigator, Autism risk, prenatal environmental exposures, and pathophysiologic markers, Hertz-Picciotto (Contact), Pessah, Ozenoff (MPI) (Principal Investigator), NIH
Principal Investigator, Mitochondrial dysfunction in HD-Affected Human Fibroblasts, (Principal Investigator), CHDI Foundation, Inc.
Co-Principal Investigator, Uncovering the molecular basis of malignant hyperthermia, Paul Allen / Issach Pessah PI on project 2 (Principal Investigator), NIH / Brigham and Womens Hospital
Co-Investigator, Genotype-phenotype relationships in fragile X families, Hagerman (Principal Investigator), NIH
Most Recent 10 Publications
Most Recent 5 Book Chapters
2003 Giulivi C, Oursler MJ: Role of mitochondrial oxygen and nitrogen reactive species in signaling. Chapter 17, M. Torres, J. Fukuto, and H. J. Forman, (ed), Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles, New York. 311-332.
1999 Giulivi C, Boveris A, Cadenas E: The steady-state concentrations of oxygen radicals in mitochondria, Daniel L. Gilbert and Carol A. Colton, (ed), Reactive Oxygen Species in Biological Systems: Selected Topics, New York, NY. 77-102.
1994 Romero FJ, Ordoñez I, Giulivi C, Cadenas E: The interaction of sulfur compounds with ferrylmyoglobin, L. Packer and E. Cadenas, (ed), Biological Oxidants and Antioxidants. 49-56.
1994 Cadenas E, Giulivi C, Ursini F, Boveris A: Electronically-excited state formation. Chapter 32, C. A. Tyson & J. M. Frazier, (ed), Methods of Toxicology, Vol. I, Part B: In Vitro Toxicity Indicators. 384-399.
1993 Giulivi C, Cadenas E: Interaction of ferrylmyoglobin with trolox, vitamin E, and unsaturated fatty acids, F. Ursini and E. Cadenas, (ed), Dietary Lipids, Antioxidants, and the Prevention of Atherosclerosis. 169-178.