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Photo: Jon Ramsey

Jon Ramsey- BS, PhD
Professor and Researcher
Molecular Biosciences

3023 VM3B
Davis, CA 95616

+1 530 754 8122


Research Focus

My research focuses on nutrition as it relates to obesity and aging. The goal of this research is to understand the biochemical mechanisms contributing to aging and obesity, and develop dietary interventions to promote weight loss and healthy aging.

Specialty Focus



1990 BS Agricultural Biochemistry, Iowa State University, Ames, IA
1995 PhD Animal Sciences, Colorado State University, Fort Collins, CO

Active Research Grants

Co-Investigator, SCHS, Mitochondria, Healthy Aging and Longevity, Gino Cortopassi (Principal Investigator), NIH NIA

Co-Investigator, Mouse Metabolic Phenotyping Center at UC Davis, KC Kent Lloyd (Principal Investigator), NIH NIDDK/NHLBI

Most Recent 10 Publications

  • Link Icon 2013 Hagopian K, Soo Hoo R, López-Domínguez JA, Ramsey JJ Calorie restriction influences key metabolic enzyme activities and markers of oxidative damage in distinct mouse liver mitochondrial sub-populations Life Sciences,
  • Link Icon 2013 Khraiwesh H, López-Domínguez JA, López-Lluch G, Navas P, de Cabo, R, Ramsey JJ, Villalba JM, González-Reyes JA Alterations of ultrastructural and fission/fusion markers in hepatocyte mitochondria from mice following calorie restriction with different dietary fats J Gerontol A Biol Sci Med Sci,
  • Link Icon 2013 López-Domínguez JA, Khraiwesh H, González-Reyes JA, López-Lluch G, Navas P, Ramsey JJ, de Cabo R, Burón MI, Villalba JM Dietary fat modifies mitochondrial and plasma membrane apoptotic signaling in skeletal muscle of calorie-restricted mice Age (Dordrecht, Netherlands),
  • Link Icon 2012 Hagopian K, Tomilov AA, Tomilova N, Kim K, Taylor SL, Lam AK, Cortopassi GA, McDonald RB, Ramsey JJ Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis Metabolism,
  • Link Icon 2012 Nagata N, Matsuo K, Bettaieb A, Bakke J, Matsuo I, Graham J, Xi Y, Liu S, Tomilov A, Tomilova N, Gray S, Jung DY, Ramsey JJ, Kim JK, Cortopassi G, Havel PJ, Haj FG Hepatic Src homology phosphatase 2 regulates energy balance in mice Endocrinology,
  • Link Icon 2012 Stern JH, Kim K, Ramsey JJ The influence of acute, late-life calorie restriction on whole body energy metabolism in p66Shc(-/-) mice Mech Ageing Dev,
  • Link Icon 2012 Chen Y, Hagopian K, Bibus D, Villalba JM, López-Lluch G, Navas P, Kim K, McDonald RB, Ramsey JJ The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction Biosci Rep,
  • Link Icon 2012 Stern JH, Kim K, Ramsey JJ The influence of shc proteins and aging on whole body energy expenditure and substrate utilization in mice PLoS One,
  • Link Icon 2012 Chen Y, Hagopian K, McDonald RB, Bibus D, López-Lluch G, Villalba JM, Navas P, Ramsey JJ The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction J Gerontol A Biol Sci Med Sci,
  • Link Icon 2012 Giorgio M, Berry A, Berniakovich I, Poletaeva I, Trinei M, Stendardo M, Hagopian K, Ramsey JJ, Cortopassi G, Migliaccio E, Nötzli S, Amrein I, Lipp HP, Cirulli F, Pelicci PG The p66Shc knocked out mice are short lived under natural condition Aging Cell,

Most Recent 5 Book Chapters

2012 Ramsey JJ: Determining Energy Requirements, Fascetti AJ, Delaney SJ, (ed), Applied Veterinary Clinical Nutrition, Ames, IA. 23-47.

2007 Ramsey JJ, Hagopian K: Bioenergetics, Birren J, (ed), Encyclopedia of Gerontology, 2nd edition, Oxford. .

2001 Ramsey, JJ, S Monemdjou, S Lal, R Weindruch, and ME Harper: Restriction of energy intake, mitochondrial proton leak and aging, A Chwalibog and K Jakobsen, (ed), Energy Metabolism of Animals, Wageningen, the Netherlands. 305-8.

1998 Ramsey, JJ, DE Johnson, and KA Johnson: Energy expenditure and mitochondrial proton leak in lean and obese strains of rats, KJ McCracken, EF Unsworth, and ARG Wylie, (ed), Energy Metabolism of Farm Animals, New York. 27-30.

1996 Johnson, DE, GM Ward and JJ Ramsey: Livestock methane: current emissions and mitigation potential, ET Kornegay, (ed), Nutrient Management of Food Animals to Enhance the Environment, Boca Raton, FL. 219-233.