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Photo: Jon Ramsey

Jon Ramsey- BS, PhD
Professor and Researcher
Molecular Biosciences

3023 VM3B
Davis, CA 95616

+1 530 754 8122
jjramsey@ucdavis.edu

   

Research Focus

My research focuses on nutrition as it relates to obesity and aging. The goal of this research is to understand the biochemical mechanisms contributing to aging and obesity, and develop dietary interventions to promote weight loss and healthy aging.

Specialty Focus

Nutrition

Education

1990 BS Agricultural Biochemistry, Iowa State University, Ames, IA
1995 PhD Animal Sciences, Colorado State University, Fort Collins, CO

Active Research Grants

Co-Investigator, SCHS, Mitochondria, Healthy Aging and Longevity, Gino Cortopassi (Principal Investigator), NIH NIA

Co-Investigator, Mouse Metabolic Phenotyping Center (MMPC) at UC Davis, KC Kent Lloyd (Principal Investigator), NIH NIDDK

Principal Investigator, Uncovering the molecular basis of Malignant Hyperthermia, (Principal Investigator), NIH

Most Recent 10 Publications

  • Jon Ramsey: Mice with low levels of Shc proteins display reduced glycolytic and increased gluconeogenic activities in liver 2016 Hagopian K, Kim K, Lopez-Dominguez JA, Tomilov A, Cortopassi GA, Ramsey JJ Mice with low levels of Shc proteins display reduced glycolytic and increased gluconeogenic activities in liver Biochem Biophys Rep ,
  • Jon Ramsey: Dietary fat composition influences glomerular and proximal convoluted tubule cell structure and autophagic processes in kidneys from calorie-restricted mice 2016 Calvo-Rubio M, Burón MI, López-Lluch G, Navas P, de Cabo R, Ramsey JJ, Villalba JM, González-Reyes JA Dietary fat composition influences glomerular and proximal convoluted tubule cell structure and autophagic processes in kidneys from calorie-restricted mice Aging cell,
  • Jon Ramsey: Omega-3 fatty acids partially revert the metabolic gene expression profile induced by long-term calorie restriction 2016 López-Domínguez JA, Cánovas Á, Medrano JF, Islas-Trejo A, Kim K, Taylor SL, Villalba JM, López-Lluch G, Navas P, Ramsey JJ Omega-3 fatty acids partially revert the metabolic gene expression profile induced by long-term calorie restriction Experimental gerontology,
  • Jon Ramsey: p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria 2016 Tomilov A, Tomilova N, Shan Y, Hagopian K, Bettaieb A, Kim K, Pelicci PG, Haj F, Ramsey J, Cortopassi G p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria The Journal of biological chemistry,
  • Jon Ramsey: Relationship between Liver Mitochondrial Respiration and Proton Leak in Low and High RFI Steers from Two Lineages of RFI Angus Bulls 2015 Acetoze G, Weber KL, Ramsey JJ, Rossow HA Relationship between Liver Mitochondrial Respiration and Proton Leak in Low and High RFI Steers from Two Lineages of RFI Angus Bulls International scholarly research notices,
  • Jon Ramsey: Influence of dietary protein level on body composition and energy expenditure in calorically restricted overweight cats 2015 des Courtis X, Wei A, Kass PH, Fascetti AJ, Graham JL, Havel PJ, Ramsey JJ Influence of dietary protein level on body composition and energy expenditure in calorically restricted overweight cats Journal of animal physiology and animal nutrition,
  • Jon Ramsey: Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins 2015 Hagopian K, Tomilov AA, Kim K, Cortopassi GA, Ramsey JJ Key glycolytic enzyme activities of skeletal muscle are decreased under fed and fasted states in mice with knocked down levels of Shc proteins PloS one,
  • Jon Ramsey: Dietary fat and aging modulate apoptotic signaling in liver of calorie-restricted mice 2015 López-Domínguez JA, Khraiwesh H, González-Reyes JA, López-Lluch G, Navas P, Ramsey JJ, de Cabo R, Burón MI, Villalba JM Dietary fat and aging modulate apoptotic signaling in liver of calorie-restricted mice The journals of gerontology. Series A, Biological sciences and medical sciences,
  • Jon Ramsey: The Influence of Dietary Fat Source on Life Span in Calorie Restricted Mice 2015 López-Domínguez JA, Ramsey JJ, Tran D, Imai DM, Koehne A, Laing ST, Griffey SM, Kim K, Taylor SL, Hagopian K, Villalba JM, López-Lluch G, Navas P, McDonald RB The Influence of Dietary Fat Source on Life Span in Calorie Restricted Mice The journals of gerontology. Series A, Biological sciences and medical sciences,
  • Jon Ramsey: The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction 2014 Chen Y, Hagopian K, Bibus D, Villalba JM, López-Lluch G, Navas P, Kim K, Ramsey JJ The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction Physiological research,

Most Recent 5 Book Chapters

2016 Ramsey JJ, Lopez-Dominguez JA, Hagopian K: The impact of aging and calorie restriction on liver mitochondria, Han D and Kaplowitz N, (ed), Mitochondria in Liver Disease, New York. 141-168.

2015 Gooding MA, McKnight LL, Ramsey JJ, Shoveller AK: Conducting indirect calorimetry studies in companion animals, Gerrits WJJ and Labussiere E, (ed), Indirect Calorimetry, techniques, computations and applications, Wageningen. 247-274.

2012 Ramsey JJ: Determining Energy Requirements, Fascetti AJ, Delaney SJ, (ed), Applied Veterinary Clinical Nutrition, Ames, IA. 23-47.

2007 Ramsey JJ, Hagopian K: Bioenergetics, Birren J, (ed), Encyclopedia of Gerontology, 2nd edition, Oxford. .

2001 Ramsey, JJ, S Monemdjou, S Lal, R Weindruch, and ME Harper: Restriction of energy intake, mitochondrial proton leak and aging, A Chwalibog and K Jakobsen, (ed), Energy Metabolism of Animals, Wageningen, the Netherlands. 305-8.