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Peter Havel- BS, DVM, PhD
Professor and Researcher
Molecular Biosciences

3426 Meyer Hall
Davis, CA 95616

+1 530 752 0882
pjhavel@ucdavis.edu

   

Research Focus

Nutrition, Metabolism, Integrative Physiology, Endocrinology, and Pharmacology.

Application of physiological, biochemical, and molecular approaches for the investigation of endocrine function and the clinical syndromes diabetes and obesity, and cardiovascular disease.

Pharmacological treatment of diabetes, obesity, and cardiovascular disease

Specialty Focus

Physiology and pathophysiology of pancreatic, gastrointestinal and adipocyte hormones, carbohydrate and lipid metabolism in humans and animals, including clinical research and studies in nonhuman primate and rodent models of obesity, diabetes and cardiovascular disease and molecular/biochemical studies using in vitro systems.

Pharmacological and nutritional prevention and treatment of diabetes and obesity, and CVD.

Education

1988 BS Zoology, University of Washington, Seattle, WA
1994 DVM , University of California, School of Veterinary Medicine, Davis
1994 PhD Area of Specialization&I#58; Pharmacology., University of California, Davis

Honors and Awards

2009 Pfizer Visiting Professor in Obesity at the University of Colorado, Denver and presented Endocrine Grand Rounds and Renal Grand Rounds in September, 2009
2006 Professional Award for original research in Human Nutrition from Grupo Bimbo Panamericano. Award presented in Mexico City, March, 2007.
2003 Academic Federation Award for Excellence in Research, Academic Federation Committee on Research, University of California, Davis.
2000 Shih-Chun Wang Award from the American Physiological Society for excellence in physiology research. (Includes $12,000 monetary award for recipient's research program)
1999 Outstanding Investigator Award, American Federation for Medical Research (Western Section). Presented at the Annual meeting in Carmel, CA
1996 New Investigator Award, North American Society for the Study of Obesity
1994 Phi Zeta Honor Society of Veterinary Medicine (Lambda Chapter)
1994 Journal Scholarship Award, Charles Louis Davis Foundation for Advancement of Veterinary and Comparative Pathology for outstanding paper in Veterinary Pathology
1991 Robert Emrie Smith Memorial Research Fellowship for research achievement, Dept of Physiological Sciences, School of Veterinary Medicine, University of California, Davis
1990-1993 Achievement Awards for College Scientists (ARCS) researchy fellowships, School of Veterinary Medicine, University of California, Davis
1990, 1991 New Investigator Travel Awards, European Association for the Study of Diabetes
1990 University of California Regents' Fellowship, Graduate Division, UC Davis
1989-1990 New Investigator Travel Awards, The Endocrine Society
1988-93 NIH Predoctoral Training Fellowship, Dept. of Nutrition, University of California, Davis

Active Research Grants

Principal Investigator, UC Office of the President Award - Stress, Socioeconomic Status, and Obesity, (Principal Investigator), UCOP/UCD

Co-Principal Investigator, Mouse Metabolic Phenotyping Center (MMPC) At UC Davis, Lloyd (Principal Investigator), NIH/NIDDK

Principal Investigator, Fatty acid sources of fructose and HFCS-induced postprandial hypertriglyceridemia, (Principal Investigator), NIH/NHLBI

Principal Investigator, Dissecting mechanisms by which IT and VSG surgery delay type 2 diabetes onset in the UCD-T2DM rat, (Principal Investigator), NIH/NIDDK

Principal Investigator, Effects of MicroRNA treatment on the development of insulin resistance and dyslipidemia in obese rhesus monkeys, (Principal Investigator), Miragen Therapeutics, Inc.

Principal Investigator, Effects of Magnamosis (magnetic anastomosis) on lipids, endocrine/metabolic parameters, meal tolerance, G.I. hormone responses, and bile acids in obese insulin-resistant rhesus monkeys , (Principal Investigator), Kids 'n' Moms Foundation

Principal Investigator, Adverse effects of dietary sugars - Ad libitum vs energy-balanced diets, (Principal Investigator), NIH/NHLBI

Principal Investigator, Evaluation of a BMS antibody in the fructose-fed rhesus monkey model of metabolic syndrome , (Principal Investigator), Bristol-Myers Squibb, Inc.

Principal Investigator, Diversity supplement for post-doctoral training for Dr. Candice Price Allister, (Principal Investigator), NIH/NHLBI

Most Recent 10 Publications

  • Peter Havel: Effects of DDT exposure on lipids and energy balance in obese Sprague-Dawley rats before and after weight loss 2015 Ishikawa T, Graham JL, Stanhope KL, Havel PJ, La Merrill MA Effects of DDT exposure on lipids and energy balance in obese Sprague-Dawley rats before and after weight loss Toxicology Reports,
  • Peter Havel: Comparison of the effect of post-heparin and pre-heparin lipoprotein lipase and hepatic triglyceride lipase on remnant lipoprotein metabolism 2015 Shirakawa T, Nakajima K, Shimomura Y, Kobayashi J, Stanhope K, Havel PJ, Machida T, Sumino H, Murakami M Comparison of the effect of post-heparin and pre-heparin lipoprotein lipase and hepatic triglyceride lipase on remnant lipoprotein metabolism Clinica Chimica Acta,
  • Peter Havel: Chronic oxytocin administration inhibits food intake, increases energy expenditure, and produces weight loss in fructose-fed obese rhesus monkeys. 2015 Blevins JE, Graham JL, Morton GJ, Bales KL, Schwartz MW, Baskin DG, Havel PJ Chronic oxytocin administration inhibits food intake, increases energy expenditure, and produces weight loss in fructose-fed obese rhesus monkeys. Am J Physiol Regul Integr Comp Physiol,
  • Peter Havel: Influence of dietary protein level on body composition and energy expenditure in calorically restricted overweight cats. 2015 des Courtis X, Wei A, Kass PH, Fascetti AJ, Graham JL, Havel PJ, Ramsey JJ Influence of dietary protein level on body composition and energy expenditure in calorically restricted overweight cats. J Anim Physiol Anim Nutr (Berl),
  • Peter Havel: Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes. 2015 Fields AJ, Berg-Johansen B, Metz LN, Miller S, La B, Liebenberg EC, Coughlin DG, Graham JL, Stanhope KL, Havel PJ, Lotz JC Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes. J Orthop Res,
  • Peter Havel: Excessive Sugar Consumption May Be a Difficult Habit to Break: A View From the Brain and Body. 2015 Tryon MS, Stanhope KL, Epel ES, Mason AE, Brown R, Medici V, Havel PJ, Laugero KD Excessive Sugar Consumption May Be a Difficult Habit to Break: A View From the Brain and Body. J Clin Endocrinol Metab,
  • Peter Havel: Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population. 2015 Vaughan LK, Wiener HW, Aslibekyan S, Allison DB, Havel PJ, Stanhope KL, O'Brien DM, Hopkins SE, Lemas DJ, Boyer BB, Tiwari HK Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population. Metabolism: clinical and experimental,
  • Peter Havel: Adiponectin May Modify the Risk of Barrett's Esophagus in Patients With Gastroesophageal Reflux Disease. 2015 Almers LM, Graham JE, Havel PJ, Corley DA Adiponectin May Modify the Risk of Barrett's Esophagus in Patients With Gastroesophageal Reflux Disease. Clin Gastroenterol Hepatol,
  • Peter Havel: A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults 2015 Stanhope KL, Medici V, Bremer AA, Lee V, Lam HD, Nunez MV, Chen GX, Keim NL, Havel PJ A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults Am J Clin Nutr,
  • Peter Havel: Differential Responses of Plasma Adropin Concentrations To Dietary Glucose or Fructose Consumption In Humans. 2015 Butler AA, St-Onge MP, Siebert EA, Medici V, Stanhope KL, Havel PJ Differential Responses of Plasma Adropin Concentrations To Dietary Glucose or Fructose Consumption In Humans. Sci Rep,

Most Recent 5 Book Chapters

2014 Stanhope KL, Havel PJ: Chapter 19: Mechanisms by which Dietary Sugars Influence Lipid Metabolism, Circulating Lipids and Lipoproteins, and Cardiovascular Risk, Goran MI, Tappy L, Le K-A, (ed), In: Dietary Sugars and Health, Boca Raton, FL. 265-380.

2014 Keim NL, Levin RJ, Havel PJ: Chapter 2: Carbohydrates, Ross AC, Caballero B, Cousins RJ, Tucker KL, Ziegler TR, (ed), In: Modern Nutrition in Health and Disease, 11th Edition, Baltimore, MD. 36-57.

2011 Havel PJ, Bremer AA: Endocrine Regulation of energy Homeostasis: Implications for Obesity and diabetes, MS Ríos, JM Ordovás, JA Gutiérrez-Fuentes, (ed), Obesity. 107-126.

2008 Havel PJ: Endocrine and metabolic consequences of consuming beverages containing glucose and/or fructose, , Issues in Cardiovascular and Metabolic Disease Risk Management, Chevy Chase, MD. 18-20.

2007 Havel PJ: Sorting out satiety and weight regulation:hormones and dietary macronutrients, G Wardlaw, (ed), Perspectives in Nutrition, 7th Edition. 479-480.