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Photo: Brian G Murphy

Brian G Murphy- BA, DVM, PhD
Assistant Professor
Pathology, Microbiology & Immunology

4315 Vet Med 3A
Davis, CA 95616

+1 530 752 9011
bmurphy@ucdavis.edu

  

Research Focus

Viral transcriptional regulation and the relationship of virus-host cell interaction to pathogenesis.

Specialty Focus

Anatomic Pathology- oral and orthopedic pathology

Retrovirology

Education

1988 BA Biology, Whitman College, Walla Walla WA
1992 DVM , Washington State University, Pullman, WA
2006 PhD Virology/Veterinary Pathology Residency, Washington State University, Pullman, WA

Honors and Awards

2000-2003 ARCS Scholarship (Achievement Rewards for College Scientists)
2003 Washington State University, Teaching Assistant Excellence Award
2004-2006 National Institutes of Health, Immunology Training Grant
2006 C.L. Davis Veterinary Pathology Scholarship
2009 Favorite Teacher Award, 2008-2009, UC Davis School of Veterinary Medicine Class of 2011
2010 Favorite Teacher Award, 2009-2010, UC Davis School of Veterinary Medicine Class of 2012
2011 Favorite Teacher Award, 2010-2011, UC Davis School of Veterinary Medicine Class of 2013
2012 Favorite Teacher Award, 2011-2012, UC Davis School of Veterinary Medicine Class of 2014

Licenses

Diplomate American College of Veterinary Pathologists

Active Research Grants

Principal Investigator, Mechanisms of FIV latency in peripheral blood monocytes, (Principal Investigator), UC Davis Center for Companion Animal Health

Principal Investigator, Pharmacokinetics and pharmacodynamics of suberoylanilide hydroxamic acid in cats, Brian Murphy and Samantha McDonnel (Principal Investigator), UC Davis Center for Companion Animal Health

Principal Investigator, Pharmacologic reactivation of latent feline immunodeficiency virus, Brian Murphy and Samantha McDonnel (Principal Investigator), UC Davis Center for Companion Animal Health

Principal Investigator, A gene therapy strategy for the production of recombinant feline erythropoietin in cats, (Principal Investigator), Morris Animal Foundation, FIRST award

Principal Investigator, Caprine arthritis encephalitis viral promoters sequenced from the milk, colostrum and mammary gland tissue of infected does demonstrate conserved features which may be important for goat-kid transmission and pathogenesis, Brian Murphy and Esperanza Lucia Duato (Principal Investigator), American Dairy Goat Association Research Foundation

Principal Investigator, Mutations in the caprine arthritis encephalitis virus determine disease outcome, Brian Murphy (Principal Investigator), Center for Food Animal Health

Most Recent 10 Publications

  • Link Icon 2012 McDonnel SJ, Sparger EE, Luciw PA, Murphy BG Pharmacologic reactivation of latent feline immunodeficiency virus ex vivo in peripheral CD4+ T-lymphocytes Virus Research,
  • Link Icon 2012 Murphy B, Vapniarsky N, Hillman C, Castillo D, McDonnel S, Moore P, Luciw P, Sparger E FIV establishes a latent infection in feline peripheral blood CD4+ T lymphocytes in vivo during the asymptomatic phase of infection Retrovirology,
  • Link Icon 2012 McDonnel SJ, Sparger EE, Luciw PA, Murphy BG Transcriptional regulation of latent feline immunodeficiency virus in peripheral CD4+ T lymphocytes Viruses,
  • Link Icon 2012 Vapniarsky N, Lame M, McDonnel S, Murphy B A lentiviral gene therapy strategy for the in vitro production of feline erythropoietin PLoS ONE,
  • Link Icon 2012 Murphy B, Hillman C, Mok M, Vapniarsky N Lentiviral latency in peripheral CD4+ T cells isolated from feline immunodeficiency virus-infected cats during the asymptomatic phase is not associated with hypermethylation of the proviral promoter Virus Research,
  • Link Icon 2012 Spriet M, Murphy B, Vallance SA, Vidal MA, Whitcomb M, Wisner E Magic Angle Magnetic Resonance Imaging of Diode Laser Induced and Naturally Occurring Lesions in Equine Tendons Veterinary Radiology and Ultrasound,
  • Link Icon 2012 Murphy B, Hillman C, Castillo D, Vapniarsky N, Rowe J The presence or absence of the gamma-activated site determines IFN gamma-mediated transcriptional activation in CAEV promoters cloned from the mammary gland and joint synovium of a single CAEV-infected goat Virus Research,
  • Link Icon 2012 Nemec A, Murphy B, Kass PH, Verstraete FJM Histologic subtypes of oral non-tonsillar squamous cell carcinoma in dogs J of Comparative Pathology,
  • Link Icon 2012 Borys D, Canter RJ, Hoch B, Martinez SR, Tamurian RM, Murphy B, Bishop J, Horvai A P16 expression predicts necrotic response among patients with osteosarcoma receiving neoadjuvant chemotherapy Human Pathology DOI: 10.1016/j.humpath.2012.02.003,
  • Link Icon 2012 Vapniarsky N, Barr BC, Murphy B Systemic Coxiella-like Infection With Myocarditis and Hepatitis in an Eclectus Parrot (Eclectus roratus) Vet Pathol,