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Photo: Robert B Rebhun

Robert B Rebhun- BS, DVM, PhD
Associate Professor and Associate Researcher
Surgical & Radiological Sciences

Center for Companion Animal Health
Davis, CA 95616

+1 530 754 5028
rbrebhun@ucdavis.edu

   

Research Focus

The Biology and Therapy of Cancer Metastasis

Specialty Focus

Comparative and Translational Oncology

Education

1995 BS Animal Science, Cornell University, Ithaca, NY
2002 DVM Veterinary Medicine, Cornell University, Ithaca, NY
2006 PhD Cancer Biology, UT Houston/M.D. Anderson Cancer Center, Houston, TX
2008 Residency Medical Oncology, Colorado State University, Fort Collins, CO

Honors and Awards

2005 - 2006 American Legion Auxiliary Fellowship in Cancer Research, University of Texas Houston/M.D. Anderson Cancer Center
2002 - 2006 Faculty/Alumni Merit Scholarship, University of Texas Houston/M.D. Anderson Cancer Center
2002 Pharmacia Veterinary Student Proficiency Award, Cornell University College of Veterinary Medicine
2002 Daphne Award for Clinical Proficiency and Excellence in the Practice of Veterinary Medicine, Cornell University College of Veterinary Medicine
2005 - 2006 American Legion Auxiliary Fellowship in Cancer Research, University of Texas Houston/M.D. Anderson Cancer Center
2002 - 2006 Faculty/Alumni Merit Scholarship, University of Texas Houston/M.D. Anderson Cancer Center
2002 Pharmacia Veterinary Student Proficiency Award, Cornell University College of Veterinary Medicine
2002 Daphne Award for Clinical Proficiency and Excellence in the Practice of Veterinary Medicine, Cornell University College of Veterinary Medicine

Licenses

State Licensure - New York, (active)
State Licensure - Texas, (inactive)
State of Colorado, Academic License, (inactive)
Diplomate American College of Veterinary Internal Medicine (Oncology)
Certified in Good Clinical Practice (GCP)

Active Research Grants

Principal Investigator, The relationship between epidermal growth factor receptor and hedgehog signaling in colon cancer, (Principal Investigator), NIH NCRR

Co-Investigator, 1 of 3 Interdisciplinary Collaboratory for Enhancing Translational Therapeutics Utilizing Biologically, Immunologically, and Metabollically Relevant Models of Breast Cancer, William Murphy (Principal Investigator),

Principal Investigator, Concordance of histology between needle-core biopsies and lymph node extirpation in canine lymphoma, (Principal Investigator), Center for Companion Animal Health

Principal Investigator, Assessment of in vivo efficacy of fluoroquinolone and carboplatin combination therapy in treating canine osteosarcoma lung metastasis, (Principal Investigator), Center for Companion Animal Health

Co-Principal Investigator, Evaluating the efficacy and mechanisms involved in treating canine OSA with the novel small molecule BMI1 inhibitor PTC-209 in combination with chemotherapy, Daniel York (Principal Investigator), Center for Companion Animal Health

Co-Investigator, Potency and stability of compounded chemotherapy drugs, Jenna Burton (Principal Investigator), Center for Companion Animal Health

Co-Investigator, Evaluation of the Use of Chemoembolization in the Treatment of Prostatic Neoplasia, William Culp (Principal Investigator), Center for Companion Animal Health

Co-Investigator, Phase II evaluation of vinblastine for the treatment of canine histiocytic sarcoma, Skorupski (Principal Investigator), Center for Companion Animal Health

Co-Investigator, Intra-arterial chemotherapy and radiotherapy to treat nasal carcinoma, William T.N. Culp (Principal Investigator), Center for Companion Animal Health

Co-Investigator, Assessment and comparison of lower urinary tract neoplasia size and location with multiple imaging modalities, William T.N. Culp (Principal Investigator), Center for Companion Animal Health

Co-Investigator, Evaluation of outcome in dogs with thymic epithelial neoplasia, William T.N. Culp (Principal Investigator), Center for Companion Animal Health

Co-Principal Investigator, A Phase I/II study of FWGP in canine lymphoma patients, (Principal Investigator), UC Davis School of Vet Med Comparative Cancer Center

Co-Investigator, Equipment Grant: Clinical Trials Refrigerator and Freezer for CCAH Dispensary, (Principal Investigator), Center for Companion Animal Health

Principal Investigator, Equipment Grant: Purchase of a new ULT (-86F) freezer, (Principal Investigator), Center for Companion Animal Health

Most Recent 10 Publications

  • Robert B Rebhun: Epigenetic regulation of human hedgehog interacting protein in glioma cell lines and primary tumor samples. 2015 Shahi MH, Zazpe I, Afzal M, Sinha S, Rebhun RB, MelĂ©ndez B, Rey JA, Castresana JS Epigenetic regulation of human hedgehog interacting protein in glioma cell lines and primary tumor samples. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,
  • Robert B Rebhun: Companion animals: Translational scientist's new best friends. 2015 Kol A, Arzi B, Athanasiou KA, Farmer DL, Nolta JA, Rebhun RB, Chen X, Griffiths LG, Verstraete FJ, Murphy CJ, Borjesson DL Companion animals: Translational scientist's new best friends. Science translational medicine,
  • Robert B Rebhun: Randomized phase III trial of piroxicam in combination with mitoxantrone or carboplatin for first-line treatment of urogenital tract transitional cell carcinoma in dogs. 2015 Allstadt SD, Rodriguez CO, Boostrom B, Rebhun RB, Skorupski KA Randomized phase III trial of piroxicam in combination with mitoxantrone or carboplatin for first-line treatment of urogenital tract transitional cell carcinoma in dogs. J Vet Intern Med,
  • Robert B Rebhun: Bacterial Urinary Tract Infections Associated with Transitional Cell Carcinoma in Dogs. 2015 Budreckis DM, Byrne BA, Pollard RE, Rebhun RB, Rodriguez CO, Skorupski KA Bacterial Urinary Tract Infections Associated with Transitional Cell Carcinoma in Dogs. J Vet Intern Med,
  • Robert B Rebhun: Evaluation of outcome and prognostic factors for dogs living greater than one year after diagnosis of osteosarcoma: 90 cases (1997-2008). 2014 Culp WT, Olea-Popelka F, Sefton J, Aldridge CF, Withrow SJ, Lafferty MH, Rebhun RB, Kent MS, Ehrhart N Evaluation of outcome and prognostic factors for dogs living greater than one year after diagnosis of osteosarcoma: 90 cases (1997-2008). J Am Vet Med Assoc,
  • Robert B Rebhun: Fasting Reduces the Incidence of Delayed-Type Vomiting Associated with Doxorubicin Treatment in Dogs with Lymphoma. 2014 Withers SS, Kass PH, Rodriguez CO, Skorupski KA, O'Brien D, Guerrero TA, Sein KD, Rebhun RB Fasting Reduces the Incidence of Delayed-Type Vomiting Associated with Doxorubicin Treatment in Dogs with Lymphoma. Transl Oncol,
  • Robert B Rebhun: Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells. 2014 Shahi MH, Holt R, Rebhun RB Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells. PLoS One,
  • Robert B Rebhun: Antitumor effects of celecoxib in COX-2 expressing and non-expressing canine melanoma cell lines. 2014 Seo KW, Coh YR, Rebhun RB, Ahn JO, Han SM, Lee HW, Youn HY Antitumor effects of celecoxib in COX-2 expressing and non-expressing canine melanoma cell lines. Res Vet Sci,
  • Robert B Rebhun: Carboplatin versus alternating carboplatin and doxorubicin for the adjuvant treatment of canine appendicular osteosarcoma: a randomized, phase III trial. 2013 Skorupski KA, Uhl JM, Szivek A, Allstadt Frazier SD, Rebhun RB, Rodriguez CO Carboplatin versus alternating carboplatin and doxorubicin for the adjuvant treatment of canine appendicular osteosarcoma: a randomized, phase III trial. Vet Comp Oncol,
  • Robert B Rebhun: Unilateral intraocular mastocytosis and anterior uveitis in a dog with subcutaneous mast cell tumors 2013 Boostrom BO, Good KL, Maggs DJ, Rebhun RB, Johns JL, Kent MS Unilateral intraocular mastocytosis and anterior uveitis in a dog with subcutaneous mast cell tumors Vet Ophthalmol,

Most Recent 5 Book Chapters

2011 Rebhun RB, Culp W: Lung Cancer, Stephen J. Withrow, David M. Vail, Rodney Page, (ed), Withrow & MacEwen's Small Animal Clinical Oncology. .