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Damian C Genetos- BA, MS, PhD
Assistant Professor and Assistant Professor in Residence and Assistant Research Scientist
Anatomy, Physiology & Cell Biology

2207 Vet Med 3B
Davis, CA 95616

+1 530 754 0146


Research Focus

Bone cell mechanotransduction; cellular and molecular biology techniques

Specialty Focus

Cell biology


1999 BA Physics, History, Indiana University, Bloomington, IN
2002 MS Physiology, Indiana University, Bloomington, IN
2005 PhD Physiology, Pennsylvania State University, Hershey, PA
2007 Skeletal mechanotransduction, UC Davis School of Medicine, Department of Orthopaedic Surgery
2010 Stem cells, UC Davis School of Veterinary Medicine, Veterinary Orthopaedic Research Lab

Honors and Awards

2011-2012 Collaborative Exchange Award, Orthopaedic Research Society
2010 Academic Federation Research Travel Grant
2009 Research award, 2009 Gordon Research Conference on Atherosclerosis, Tilton, NH
2008-2011 NIH Individual National Research Service Award
2002 Young Investigator Award, Fourth Bone Fluid Flow meeting, Amsterdam, The Netherlands
2001-2004 NASA Pre-doctoral fellow

Active Research Grants

Principal Investigator, Regulation of vascular calcification by sclerostin, (Principal Investigator), American Heart Association

Most Recent 10 Publications

  • Link Icon 2012 Toupadakis CA, Wong A, Genetos DC, Chung DJ, Murugesh D, Anderson MJ, Loots GG, Christiansen BA, Kapatkin AS, Yellowley CE Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair Journal of orthopaedic research : official publication of the Orthopaedic Research Society,
  • Link Icon 2012 Genetos DC, Zhou Z, Li Z, Donahue HJ Age-related changes in gap junctional intercellular communication in osteoblastic cells Journal of orthopaedic research : official publication of the Orthopaedic Research Society,
  • Link Icon 2012 Collette NM, Genetos DC, Economides AN, Xie L, Shahnazari M, Yao W, Lane NE, Harland RM, Loots GG Targeted Deletion of Sost Distal Enhancer Increases Bone Formation and Bone Mass Proc Natl Acad Sci USA,
  • Link Icon 2012 Morales-Hernandez D, Genetos DC, Working DM, Murphy KC, Leach JK Ceramic identity contributes to mechanical properties and osteoblast behavior on macroporous composite scaffolds J Funct Biomater,
  • Link Icon 2012 Hoch AI, Binder BY, Genetos DC, Leach JK Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells PLoS ONE,
  • Link Icon 2012 Watari S, Hayashi K, Wood JA, Russell P, Nealey PF, CJ Murphy CJ, Genetos DC Modulation of osteogenic differentiation in hMSCs cells by submicron topographically-patterned ridges and grooves Biomaterials,
  • Link Icon 2012 Loots GG, Keller H, Leupin O, Murugesh D, Collette NM, Genetos DC TGF-ß regulates sclerostin expression via the ECR5 enhancer Bone,
  • Link Icon 2011 Morgan JM, Wong A, Yellowley CE, Genetos DC Regulation of tenascin expression in bone J Cell Biochem,
  • Link Icon 2011 Davis HE, Case EM, Miller SL, Genetos DC, Leach JK Osteogenic response to BMP-2 of hMSCs grown on apatite-coated scaffolds Biotechnol Bioeng,
  • Link Icon 2011 Genetos DC, Karin NJ, Geist DJ, Donahue HJ, Duncan RL Purinergic signaling is required for fluid shear stress-induced NF-?B translocation in osteoblasts Exp Cell Res,

Most Recent 5 Book Chapters

2012 Genetos DC, Jacobs CR: Bone cell mechanoresponsiveness, X.E. Guo and M.R. Silva, (ed), Skeletal Aging and Osteoporosis: Biomechanics and Mechanobiology. 177-90.

2005 Duncan RL, Genetos DC: Calcium signaling in osteoblasts in response to mechanical stimulation, R. Aaron and M. Bolander, (ed), Physical Regulation of Skeletal Repair, Rosemont, IL. .