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| Damian C Genetos- BA, MS, PhD
Assistant Professor and Assistant Professor in Residence and Assistant Research Scientist
Anatomy, Physiology & Cell Biology
2328 Vet Med 3A
Davis, CA 95616 +1 530 754 6865
dgenetos@ucdavis.edu |
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Research Focus | Bone cell mechanotransduction; cellular and molecular biology techniques |
Specialty Focus | Cell biology |
Education |
1999 BA Physics, History, Indiana University, Bloomington, IN
2002 MS Physiology, Indiana University, Bloomington, IN
2005 PhD Physiology, Pennsylvania State University, Hershey, PA
2007 Skeletal mechanotransduction, UC Davis School of Medicine, Department of Orthopaedic Surgery
2010 Stem cells, UC Davis School of Veterinary Medicine, Veterinary Orthopaedic Research Lab
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Honors and Awards |
2001-2004 NASA Pre-doctoral fellow
2002 Young Investigator Award, Fourth Bone Fluid Flow meeting, Amsterdam, The Netherlands
2008-2011 NIH Individual National Research Service Award
2009 Research award, 2009 Gordon Research Conference on Atherosclerosis, Tilton, NH
2010 Academic Federation Research Travel Grant
2011-2012 Collaborative Exchange Award, Orthopaedic Research Society
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Active Research Grants | Principal Investigator, Regulation of sclerostin expression by hypoxia: A proposed mechanism to explain hypoxia-driven bone formation, (Principal Investigator), NIH Principal Investigator, Controlled delivery of local PTH speeds the osteogenic differentiation of BMSCs and enhances repair of critical-sized cranial defects, (Principal Investigator), UC Center for Equine Health, Randall Project Principal Investigator, Regulation of vascular calcification by sclerostin, (Principal Investigator), American Heart Association |
Most Recent 10 Publications |  2012 Collette NM, Genetos DC, Economides AN, Xie L,
Shahnazari M, Yao W, Lane NE, Harland RM, Loots GG Targeted Deletion of Sost Distal Enhancer Increases Bone Formation and Bone Mass Proc Natl Acad Sci USA,- 2012 Morales-Hernandez D, Genetos DC, Working DM, Murphy KC, Leach JK Ceramic identity contributes to mechanical properties and
osteoblast behavior on macroporous composite scaffolds J Funct Biomater,
- 2012 Hoch AI, Binder BY, Genetos DC, Leach JK Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells PLoS ONE,
- 2012 Watari S, Hayashi K, Wood JA, Russell P, Nealey PF, CJ Murphy CJ,
Genetos DC Modulation of osteogenic differentiation in hMSCs cells by submicron topographically-patterned ridges and grooves Biomaterials,
- 2012 Loots GG, Keller H, Leupin O, Murugesh D, Collette NM, Genetos DC TGF-ß regulates sclerostin expression via the ECR5 enhancer Bone,
- 2011 Morgan JM, Wong A, Yellowley CE, Genetos DC Regulation of tenascin expression in bone J Cell Biochem,
- 2011 Davis HE, Case EM, Miller SL, Genetos DC, Leach JK Osteogenic response to BMP-2 of hMSCs grown on apatite-coated scaffolds Biotechnol Bioeng,
- 2011 Genetos DC, Karin NJ, Geist DJ, Donahue HJ, Duncan RL Purinergic signaling is required for fluid shear stress-induced NF-?B translocation in osteoblasts Exp Cell Res,
- 2011 Raheja LF, Genetos DC, Wong A, Yellowley CE Hypoxic regulation of mesenchymal stem cell migration: the role of RhoA and HIF-1a Cell Biol Int,
- 2011 Morgan JM, Wong A, Genetos DC, Yellowley CE Src is sufficient, but not necessary, for osteopontin induction in osteoblasts Biorheology,
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Most Recent 5 Book Chapters | 2012 Genetos DC, Jacobs CR: Bone cell mechanoresponsiveness, X.E. Guo and M.R. Silva, (ed),
Skeletal Aging and Osteoporosis: Biomechanics and Mechanobiology. 177-90. 2005 Duncan RL, Genetos DC: Calcium signaling in osteoblasts in response to mechanical stimulation, R. Aaron and M. Bolander, (ed),
Physical Regulation of Skeletal Repair, Rosemont, IL. . |
