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Photo: Heather Knych

Heather Knych- BS, DVM, MS, PhD
Associate Professor of Clinical
California Animal Health and Food Safety Lab

K.L. Maddy Equine Analytical Chemistry Laboratory
Davis, CA 95616

+1 530 752 8700
hkknych@ucdavis.edu

   

Research Focus

Equine: pharmacokinetics/pharmacodynamics; drug metabolism; biomarkers

Specialty Focus

Equine pharmacology

Education

2010 Residency American College of Veterinary Clinical Pharmacology Residency, University of California, Davis, Davis, CA
2008 PhD Pharmacology and Toxicology, University of California, Davis, Davis, CA
2005 DVM , University of California, Davis, Davis, CA
2000 MS Physiology, San Jose State University, San Jose, CA
1997 BS Biochemistry and Cell Biology, University of California, San Diego, LaJolla, CA

Licenses

Diplomate of the American College of Clinical Veterinary Pharmacology
DVM, California

Active Research Grants

Principal Investigator, Characterization of Intra-Articular Isoflupredone, (Principal Investigator), Grayson Jockey Club

Principal Investigator, Pharmacokinetics and Selected Physiological and Behavioral Responses of Trazodone Following Intravenous Administration to Exercised Horses, (Principal Investigator), Center for Equine Health, University of California, Davis

Co-Investigator, Pharmacokinetics of chloramphenicol in healthy horses, Gary Magdesian (Principal Investigator), Center for Equine Health, University of California, Davis

Most Recent 10 Publications

  • Link Icon 2015 Molter, C., Barbosa, L., Johnson, S., Chinnadurai, S., Knych, H., Wack, R. Pharmacokinetics of a Single Subcutaneous Dose of Sustained Release Buprenorphine in Northern Elephant Seals (Mirounga Angustirostris) Journal of Zoo and Wildlife Medicine,
  • Link Icon 2015 Knych, HK, Steinmetz, SJ and McKemie, DS Endogenous Concentrations and Pharmacokinetics and Behavioral Effects of Exogenous GABA Administration in Horses Journal of Veterinary Pharmacology and Therapeutics,
  • Link Icon 2015 Knych HK, Steffey EP, Mitchell M, Casbeer HC Effects of Age on the Pharmacokinetics and Selected Pharmacodynamics of Intravenously Administered Fentanyl in Foals Equine Veterinary Journal,
  • Link Icon 2015 Knych HK, Arthur RA, Stanley SD, McKemie DS Disposition and Metabolic Profile of the Weak Androgen Dehydroepiandrosterone (DHEA) Following Administration as Part of a Nutritional Supplement to Exercised Horses Drug Testing and Analysis,
  • Link Icon 2014 Knych, H.K., Steffey, E.P., White A.M., McKemie, D.S. Effects of Age on the Pharmacokinetics of Tramadol and its Active Metabolite, O-desmethyltramadol Following Intravenous Administration to Foals Equine Veterinary Journal,
  • Link Icon 2014 Gustavsen KA, Guzman DS, Knych HK, Petritz OA, Olsen GH, Paul-Murphy JR Pharmacokinetics of buprenorphine hydrochloride following intramuscular and intravenous administration to American kestrels (Falco sparverius) American Journal of Veterinary Research,
  • Link Icon 2014 Knych HK, Steffey EP, McKemie DS Preliminary pharmacokinetics of morphine and its major metabolites following intravenous administration of four doses to horses J Vet Pharmacol Therap,
  • Link Icon 2014 Knych HK, Stanley SD, Arthur RA, Mitchell MM Detection and pharmacokinetics of three formulations of firocoxib following multiple administrations to horses Equine Veterinary Journal,
  • Link Icon 2014 Guedes AG, Knych HK, Soares J, Brosnan R Pharmacokinetics and physiologic effects of repeated oral administrations of tramadol in horses J Vet Pharmacol Therap DOI: 10.1111/jvp.12086,
  • Link Icon 2014 Knych HK, Stanley SD Effects of Three Reversal Agents on Sublingually Administered Detomidine Induced Changes in Behavior, Cardiac and Selected Blood Parameters in the Horse J Vet Pharmacol Therap DOI: 10.1111/vaa.12081,

Most Recent 5 Book Chapters

2014 Knych HK: Chapter 13: Analgesic Pharmacology, , Robinson's Current Therapy in Equine Medicine, 7th Edition. 55-57.