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Photo: Heather Knych

Heather Knych- BS, DVM, MS, PhD
Assistant Professor of Clinical
Molecular Biosciences


hkknych@ucdavis.edu

   

Research Focus

Equine: Pharmacokinetics/Pharmacodynamics; Drug metabolism; Biomarkers

Specialty Focus

California Animal Health & Food Safety Laboratory System

Education

2010 Residency American College of Veterinary Clinical Pharmacology Residency, University of California, Davis, Davis, CA
2008 PhD Pharmacology and Toxicology, University of California, Davis, Davis, CA
2005 DVM , University of California, Davis, Davis, CA
2000 MS Physiology, San Jose State University, San Jose, CA
1997 BS Biochemistry and Cell Biology, University of California, San Diego, LaJolla, CA

Licenses

Diplomate of the American College of Clinical Veterinary Pharmacology
DVM, California

Active Research Grants

Principal Investigator, Phamacokinetics, Clinical Effects and Biomarkers of Corticosteroids in Horses, (Principal Investigator), Racing Medication and Testing Consortieum

Principal Investigator, Detection, Pharmacokinetics, Pharmacodynamics and Differential Expression of Skeletal Muscle Genes Following Administration of VentipulminĀ® to Exercised Horses, (Principal Investigator), Boehringer Ingelheim Vetmedica

Co-Investigator, Pharmacokinetics of metronidazole in neonatal foals, Gary Magdesian (Principal Investigator), Center for Equine Health

Co-Investigator, Pharmacokinetics and analgesic effects of a soluble epoxide hydrolase inhibitor in a reversible inflammatory model of joint pain in horses, Dr. Alonso Guedes (Principal Investigator), Center for Equine Health

Most Recent 10 Publications

  • Link Icon 2012 Knych HK, Corado CR, McKemie DS, Scholtz E, Sams R Pharmacokinetics and Pharmacodynamics of Tramadol in Horses Following Oral Administration Journal of Veterinary Pharmacology and Therapeutics,
  • Link Icon 2012 Knych HK, Casbeer HC, McKemie DS, Arthur RM Pharmacokinetics and pharmacodynamics of butorphanol following intravenous administration to the horse J Vet Pharmacol Ther,
  • Link Icon 2012 Knych HK, Corado CR, McKemie DS, Steffey EP Pharmacokinetics and Selected Physiologic Effects of Tramadol Following Intravenous Administration to the Horse Equine Veterinary Journal,
  • Link Icon 2012 Knych HK, Steffey EP, Stanley SD The effect of yohimbine on the pharmacokinetic parameters of detomidine in the horse Vet Anaesth Analg,
  • Link Icon 2011 Hilton HG., Magdeisan KG, Groth AD, Knych H, Stanley SD, Hollingsworth SR Distribution of flunixin meglumine and firocoxib into aqueous humor of horses J Vet Intern Med,
  • Link Icon 2011 DiMaio Knych HK, Steffey EP, Deuel JL, Shepard RA, Stanley SD Pharmacokinetics of yohimbine following intravenous administration to horses J Vet Pharmacol Ther,
  • Link Icon 2011 Pavez JC, Hawkins MG, Pascoe PJ, Kynch HK, Kass PH Effect of fentanyl target-controlled infusions on isoflurane minimum anaesthetic concentration and cardiovascular function in red-tailed hawks (Buteo jamaicensis) Veterinary Anaesthesia and Analgesia (letter),
  • Link Icon 2011 DiMaio Knych HK, Stanley SD Pharmacokinetics and Pharmacodynamics of Detomidine Following Sublingual Administration to Horses Am J Vet Res (letter),
  • Link Icon 2010 Stanley SD, DiMaio Knych HK Comparison of Pharmaceutical Equivalence for Compounded Preparations of Pergolide Mesylate Proceedings of the 56th American Association of Equine Practitioners,
  • Link Icon 2010 DiMaio Knych HK, Taylor A, Arthur RM and Stanley SD Comparative pharmacokinetics of two oral formulations of Dantrolene in the horse Proceedings of the American Association of Equine Practitioners,