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Photo: Guillaume de Lartigue

Guillaume de Lartigue- BS, PhD
Assistant Project Scientist
Anatomy, Physiology & Cell Biology


gdelartigue@ucdavis.edu

   

Research Focus

Determining the cellular and molecular mechanisms in vagal afferent neurons involved in the control of feeding behavior, and understanding the role of these neurons in the pathophysiology of obesity using models of diet-induced obesity.

Specialty Focus

Gut-brain signaling; feeding behavior

Education

2002 BS Medical Biochemistry, Royal Holloway, University of London, United Kingdom
2007 PhD Physiology, University of Liverpool, United Kingdom

Honors and Awards

2006 Best Poster award, Wellcome Trust PhD conference, London
2007 Keystone Symposia Scholarship
2008 Calam Travelling Fellowship
2008 Recipient of the 2008 Burgen Award
2010 Selected to give presentation at the SSAT presidential session at DDW
2012 Selected to attend Little Brain Big Brain conference
2012 Selected by peers to represent the best of Little Brain Big Brain at NGM2012

Most Recent 10 Publications

  • Link Icon 2012 de Lartigue G, Barbier de la Serre C, Espero E, Lee J, Raybould HE Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats PLoS One,
  • Link Icon 2012 Chichlowski M, de Lartigue G, German JB, Raybould HE, Mills DA Bifidobacteria Isolated from Infants and Cultured on Human Milk Oligosaccharides Affect Intestinal Epithelial Function Journal of Pediatric Gastroenterology & Nutrition,
  • Link Icon 2011 de Lartigue G, de La Serre CB, Raybould HE Vagal afferent neurons in high fat diet-induced obesity; intestinal microflora, gut inflammation and cholecystokinin Physiol Behav,
  • Link Icon 2011 de Lartigue G, Barbier de la Serre C, Espero E, Lee J, Raybould HE Diet-induced obesity leads to the development of leptin resistance in vagal afferent neurons Am J Physiol Endocrinol Metab,
  • Link Icon 2011 Lee J, Martin E, Paulino G, de Lartigue G, Raybould HE Effect of ghrelin receptor antagonist on meal patterns in cholecystokinin type 1 receptor null mice Physiol Behav,
  • Link Icon 2010 de Lartigue G, Lur G, Dimaline R, Varro A, Raybould H, Dockray GJ EGR1 Is a target for cooperative interactions between cholecystokinin and leptin, and inhibition by ghrelin, in vagal afferent neurons Endocrinology,
  • Link Icon 2010 de Lartigue G, Dimaline R, Varro A, Raybould H, De la Serre CB, Dockray GJ Cocaine- and amphetamine-regulated transcript mediates the actions of cholecystokinin on rat vagal afferent neurons Gastroenterology,
  • Link Icon 2008 Burdyga G, de Lartigue G, Raybould HE, Morris R, Dimaline R, Varro A, Thompson DG, Dockray GJ Cholecystokinin regulates expression of Y2 receptors in vagal afferent neurons serving the stomach J Neurosci,
  • Link Icon 2007 de Lartigue G, Dimaline R, Varro A, Dockray GJ Cocaine- and amphetamine-regulated transcript: stimulation of expression in rat vagal afferent neurons by cholecystokinin and suppression by ghrelin J Neurosci,

Most Recent 5 Book Chapters

2012 de Lartigue G, Raybould HE.: The Gastrointestinal Tract and Control of Food Intake, Johnson LR, Ghishan FK, Kaunitz JD, Merchant J, Said HM, Wood J, (ed), Physiology of the Gastrointestinal tract, London, UK; Waltham MA, USA; San Diego, CA, USA. 1963-78.