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Photo: Ana Cristina G Grodzki

Ana Cristina G Grodzki- BS, MS, PhD
Assistant Project Scientist
Molecular Biosciences

2011 VM3B
Davis, CA 95616


Research Focus

  • The effects of organophosphorus pesticides (OPs), on nerve-immune cell interactions implicated in airway hyperreactivity.
  • The effects of drugs modulating inflammatory response.

Specialty Focus

Cellular biology, molecular biology, immunology, neurobiology and toxicology


2010 Post- doctoral Lung biology, UC Davis, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, 451 Health Sciences Drive, GBSF, Davis, CA
2009 Post-doctoral Immunology - Mast cell Intracellular signaling, National Institutes of Health (NIH), National Institute of Dental and Craniofacial Research (NIDCR), Bethesda, MD
2003 PhD Cellular and Molecular Biology, University of Sao Paulo, Faculty of Medicine of Ribeirao Preto, Ribeirao Preto, Sao Paulo, Brazil
1999 MS Cell Biology, Federal University of Parana, Curitiba, Parana, Brazil
1996 BS Biology, Federal University of Parana, Curitiba, Parana, Brazil

Honors and Awards

2001 Award for Best Scientific Presentation in International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils - National Institutes of Health, Bethesda, MD.
2000 Award for young investigator for Excellence in Research - Junqueira Award in SIMEC 2000 - International Symposium on Extracellular Matrix, Angra dos Reis, Rio de Janeiro, Brazil.
1999-2003 PhD. Scholarship from FAPESP - The Foundation of Support for Research of the State of Sao Paulo, Brazil.
1997-1999 Masters Scholarship from CNPq - National Council for Scientific and Technological Development, Brazil.
1992-1996 Scientific Initiation from CNPq - National Council for Scientific and Thecnological Develpment, Brazil.

Active Research Grants

Assistant Researcher, Role of macrophages in organophosphorus pesticide-induced airway hyperreactivity, Pamela Lein (Principal Investigator), NIH NIEHS

Assistant Researcher, Intellectual Developmental Delay Research Center (IDDRC), Lenard Abbeduto (Principal Investigator), NIH/NICHD

Most Recent 10 Publications

  • Link Icon 2013 Grodzki AC, Giulivi C, Lein PJ Oxygen tension modulates differentiation and primary macrophage functions in the human monocytic THP-1 cell line PLoS One,
  • Link Icon 2011 Grodzki AC, Ghogha A, Mangini L, Fryer AD, Lein PJ IFN? Increases M2 Muscarinic Receptor Expression in Cultured Sympathetic Neurons Current Neurobiology,
  • Link Icon 2010 Jamur MC, Moreno AN, Mello LF, Souza Júnior DA, Campos MR, Pastor MV, Grodzki AC, Silva DC, Oliver C Mast cell repopulation of the peritoneal cavity: contribution of mast cell progenitors versus bone marrow derived committed mast cell precursors BMC Immunol,
  • Link Icon 2009 Grodzki AC, Moon KD, Berenstein EH, Siraganian RP FcepsilonRI-induced activation by low antigen concentrations results in nuclear signals in the absence of degranulation Molecular immunology,
  • Link Icon 2008 Guiraldelli MF, Berenstein EH, Grodzki AC, Siraganian RP, Jamur MC, Oliver C The low affinity IgG receptor Fc gamma RIIB contributes to the binding of the mast cell specific antibody, mAb BGD6 Molecular immunology,
  • Link Icon 2007 Ganguly S, Grodzki C, Sugden D, Møller M, Odom S, Gaildrat P, Gery I, Siraganian RP, Rivera J, Klein DC Neural adrenergic/cyclic AMP regulation of the immunoglobulin E receptor alpha-subunit expression in the mammalian pinealocyte: a neuroendocrine/immune response link? J Biol Chem,
  • Link Icon 2005 Jamur MC, Grodzki AC, Berenstein EH, Hamawy MM, Siraganian RP, Oliver C Identification and characterization of undifferentiated mast cells in mouse bone marrow Blood,
  • Link Icon 2004 Hitomi T, Zhang J, Nicoletti LM, Grodzki AC, Jamur MC, Oliver C, Siraganian RP Phospholipase D1 regulates high-affinity IgE receptor-induced mast cell degranulation Blood,
  • Link Icon 2003 Grodzki AC, Pástor MV, Sousa JF, Oliver C, Jamur MC Differential expression of integrin subunits on adherent and nonadherent mast cells Brazilian journal of medical and biological research,
  • Link Icon 2001 Jamur MC, Grodzki AC, Moreno AN, de Mello Lde F, Pastor MV, Berenstein EH, Siraganian RP, Oliver C Identification and isolation of rat bone marrow-derived mast cells using the mast cell-specific monoclonal antibody AA4 The journal of histochemistry and cytochemistry: official journal of the Histochemistry Society,

Most Recent 5 Book Chapters

2010 Grodzki AC, Berenstein E: Antibody purification: affinity chromatography - protein A and protein G Sepharose., , Methods Mol Biol. 33-41.

2010 Grodzki AC, Berenstein E: Antibody purification: ion-exchange chromatography., , Methods Mol Biol. 27-32.

2010 Grodzki AC, Berenstein E: Antibody purification: ammonium sulfate fractionation or gel filtration., , Methods Mol Biol. 15-26.

2010 Grodzki AC, Berenstein E: Introduction to the purification of antibodies., , Methods Mol Biol. 11-3.