Search for Faculty

Photo: Stephen J McSorley

Stephen J McSorley- BSc, PhD
Professor in Residence and Researcher
Anatomy, Physiology & Cell Biology

County Rd 98 at Hutchison Drive
Davis, CA 95616

+1 530 752 3414
sjmcsorley@ucdavis.edu

   

Research Focus

My research focuses on the innate and adaptive immune response to bacterial pathogens and largely uses mouse models of infection with Salmonella and Chlamydia.

Specialty Focus

Immunology and Microbiology

Education

1992 B.Sc. Immunology, Glasgow University, Glasgow, Scotland
1996 Ph.D. Immunology, Glasgow University, Glasgow, Scotland

Honors and Awards

1998-2001 Irvington Institute of Immunology Fellow
1995-1996 Federation Pour La Recherche Medicale Postdoctoral Fellowship

Active Research Grants

Principal Investigator, Innate immune response to bacterial flagellins, (Principal Investigator), NIH/NIAID

Principal Investigator, Protective immunity against typhoid, (Principal Investigator), NIH/NIAID

Principal Investigator, Generation of a TCR transgenic mouse to study Chlamydia genital tract infection, (Principal Investigator), NIH/NIAID

Co-Investigator, Functional Plasticity in the Helicobacter Pylori Type IV Secretion System, Jay Solnick (Principal Investigator), NIH/NIAID

Principal Investigator, CD4 T cell Responses to Chlamydia Infection, (Principal Investigator), NIH/NIAID

Most Recent 10 Publications

  • Stephen J McSorley: Absence of TLR11 does not confer susceptibility to Salmonella Typhi 2016 Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Baumler AJ, Pier GB, Galán JE, Yarovinsky F Absence of TLR11 does not confer susceptibility to Salmonella Typhi Cell,
  • Stephen J McSorley: Contaminated water delivery as a simple and effective means of experimental Salmonella infection 2015 O’Donnell H, Pham O, Benoun J, Ravesloot-Chavez MM, McSorley SJ Contaminated water delivery as a simple and effective means of experimental Salmonella infection Future Microbiol.,
  • Stephen J McSorley: Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria 2015 Mooney JP, Lee SJ, Lokken KL, Nanton MR, Nuccio SP, McSorley SJ, Tsolis RM Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria PLoS Neglected Tropical Diseases,
  • Stephen J McSorley: Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation 2015 Di Niro R, Lee SJ, Vander Heiden JA, Elsner RA, Trivedi N, Bannock JM, Gupta NT, Kleinstein SH, Vigneault F, Gilbert TJ, Meffre E, McSorley SJ, Shlomchik MJ. Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation Immunity,
  • Stephen J McSorley: Divergent behavior of mucosal memory T cells 2015 Pham OH, McSorley SJ Divergent behavior of mucosal memory T cells Mucosal Immunology,
  • Stephen J McSorley: Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9. 2015 Atif SM, Lee SJ, Li LX, Uematsu S, Akira S, Gorjestani S, Lin X, Schweighoffer E, Tybulewicz VL, McSorley SJ Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9. Eur J Immunol,
  • Stephen J McSorley: A re-evaluation of the role of B cells in protective immunity to Chlamydia infection. 2015 Li LX, McSorley SJ A re-evaluation of the role of B cells in protective immunity to Chlamydia infection. Immunology letters,
  • Stephen J McSorley: Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development. 2015 Nanton MR, Lee SJ, Atif SM, Nuccio SP, Taylor JJ, Bäumler AJ, Way SS, McSorley SJ Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development. Eur J Immunol,
  • Stephen J McSorley: Protective host immune responses to Salmonella infection. 2015 Pham OH, McSorley SJ Protective host immune responses to Salmonella infection. Future microbiology,
  • Stephen J McSorley: CD103-CD11b+ dendritic cells regulate the sensitivity of CD4 T-cell responses to bacterial flagellin. 2014 Atif SM, Uematsu S, Akira S, McSorley SJ CD103-CD11b+ dendritic cells regulate the sensitivity of CD4 T-cell responses to bacterial flagellin. Mucosal immunology,

Most Recent 5 Book Chapters

2012 Atif SM, McSorley SJ: TLR5, Choi S, (ed), Encyclopedia of Signaling Molecules, New York. 1875-1881.

2009 Moon JJ, McSorley SJ: Tracking the dynamics of salmonella specific T cell responses, , Curr Top Microbiol Immunol. 179-98.

1998 McSorley SJ, Liew FYI: Leishmaniasis, Delves PJ, (ed), Encyclopedia of Immunology (Second Edition). 1546–1551.

1998 McSorley SJ, F Liew Y: Nitric Oxide, Delves PJ, (ed), Encyclopedia of Immunology (Second Edition). 1859–1861.