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Photo: Stephen J McSorley

Stephen J McSorley- BSc, PhD
Professor in Residence and Researcher
Anatomy, Physiology & Cell Biology

County Rd 98 at Hutchison Drive
Davis, CA 95616

+1 530 752 3414


Research Focus

My research focuses on the innate and adaptive immune response to bacterial pathogens and largely uses mouse models of infection with Salmonella and Chlamydia.

Specialty Focus

Immunology and Microbiology


1992 B.Sc. Immunology, Glasgow University, Glasgow, Scotland
1996 Ph.D. Immunology, Glasgow University, Glasgow, Scotland

Honors and Awards

1998-2001 Irvington Institute of Immunology Fellow
1995-1996 Federation Pour La Recherche Medicale Postdoctoral Fellowship

Active Research Grants

Principal Investigator, Innate immune response to bacterial flagellins, (Principal Investigator), NIH/NIAID

Principal Investigator, Protective immunity against typhoid, (Principal Investigator), NIH/NIAID

Principal Investigator, Generation of a TCR transgenic mouse to study Chlamydia genital tract infection, (Principal Investigator), NIH/NIAID

Co-Investigator, Functional Plasticity in the Helicobacter Pylori Type IV Secretion System, Jay Solnick (Principal Investigator), NIH/NIAID

Most Recent 10 Publications

  • Link Icon 2015 Atif, SM, Lee, SJ, Li, LX, Uematsu, S, Akira, S, Gorjestani, S, Lin, X, Schweighoffer, E, Tybulewicz, VL, McSorley, SJ Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9. European journal of immunology,
  • Link Icon 2015 Li, LX, McSorley, SJ A re-evaluation of the role of B cells in protective immunity to Chlamydia infection. Immunology letters,
  • Link Icon 2015 Nanton, MR, Lee, SJ, Atif, SM, Nuccio, SP, Taylor, JJ, Bäumler, AJ, Way, SS, McSorley, SJ Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development. European journal of immunology,
  • Link Icon 2015 Pham, OH, McSorley, SJ Protective host immune responses to Salmonella infection. Future microbiology,
  • Link Icon 2014 Atif, SM, Uematsu, S, Akira, S, McSorley, SJ CD103-CD11b+ dendritic cells regulate the sensitivity of CD4 T-cell responses to bacterial flagellin. Mucosal immunology,
  • Link Icon 2014 Atif, SM, Winter, SE, Winter, MG, McSorley, SJ, Bäumler, AJ Salmonella enterica serovar Typhi impairs CD4 T cell responses by reducing antigen availability. Infection and immunity,
  • Link Icon 2014 McSorley, SJ Immunity to intestinal pathogens: lessons learned from Salmonella. Immunological reviews,
  • Link Icon 2014 McSorley, SJ The Role of Non-Cognate T Cell Stimulation during Intracellular Bacterial Infection. Frontiers in immunology,
  • Link Icon 2014 McSorley, SJ, Khoruts, A Introduction to special issue on microbiome influences on host immunity. Immunology letters,
  • Link Icon 2014 O'Donnell, H, McSorley, SJ Salmonella as a model for non-cognate Th1 cell stimulation. Frontiers in immunology,

Most Recent 5 Book Chapters

2012 Atif SM, McSorley SJ: TLR5, Choi S, (ed), Encyclopedia of Signaling Molecules, New York. 1875-1881.

2009 Moon JJ, McSorley SJ: Tracking the dynamics of salmonella specific T cell responses, , Curr Top Microbiol Immunol. 179-98.

1998 McSorley SJ, Liew FYI: Leishmaniasis, Delves PJ, (ed), Encyclopedia of Immunology (Second Edition). 1546–1551.

1998 McSorley SJ, F Liew Y: Nitric Oxide, Delves PJ, (ed), Encyclopedia of Immunology (Second Edition). 1859–1861.