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Photo: Stephen J McSorley

Stephen J McSorley- BSc, PhD
Associate Professor
Anatomy, Physiology & Cell Biology

County Rd 98 at Hutchison Drive
Davis, CA 95616

+1 530 752 3414
sjmcsorley@ucdavis.edu

  

Research Focus

Immunity to salmonella

Specialty Focus

Immunology

Education

1992 B.Sc. Immunology, Glasgow University, Glasgow, Scotland
1996 Ph.D. Immunology, Glasgow University, Glasgow, Scotland

Honors and Awards

1995-1996 Federation Pour La Recherche Medicale Postdoctoral Fellowship
1998-2001 Irvington Institute of Immunology Fellow

Active Research Grants

Principal Investigator, CD4 T cell responses to Salmonella, (Principal Investigator), NIAID

Principal Investigator, Typhoid priority antigen identification and vaccine development, (Principal Investigator), NIAID, RO1

Principal Investigator, Innate immune response to bacterial flagellins, (Principal Investigator), NIAID, RO1

Principal Investigator, Protective immunity against typhoid, (Principal Investigator), NIAID, PO1

Principal Investigator, Typhoid priority antigen identification and vaccine development, (Principal Investigator), NIAID, RO1

Most Recent 10 Publications

  • Link Icon 2011 Griffin AJ, McSorley SJ Generation of Salmonella-specific Th1 cells requires sustained antigen stimulation Vaccine,
  • Link Icon 2011 Griffin AJ, Li LX, Voedisch S, Pabst O, McSorley SJ Dissemination of persistent intestinal bacteria via the mesenteric lymph nodes causes typhoid relapse Infect Immun,
  • Link Icon 2011 Letran SE, Lee SJ, Atif SM, Flores-Langarica A, Uematsu S, Akira S, Cunningham AF, McSorley SJ TLR5-Deficient Mice Lack Basal Inflammatory and Metabolic Defects but Exhibit Impaired CD4 T Cell Responses to a Flagellated Pathogen J Immunol,
  • Link Icon 2010 Khanna KM, Blair DA, Vella AT, McSorley SJ, Datta SK, Lefran├žois L T cell and APC dynamics in situ control the outcome of vaccination J Immunol,
  • Link Icon 2010 Lee SJ, O'Donnell H, McSorley SJ B7-H1 (programmed cell death ligand 1) is required for the development of multifunctional Th1 cells and immunity to primary, but not secondary, Salmonella infection J Immunol,
  • Link Icon 2010 Jackson A, Nanton MR, O'Donnell H, Akue AD, McSorley SJ Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly J Immunol,
  • Link Icon 2010 Letran SE, Lee SJ, Atif SM, Uematsu S, Akira S, McSorley SJ TLR5 functions as an endocytic receptor to enhance flagellin-specific adaptive immunity Eur J Immunol,
  • Link Icon 2009 Srinivasan A, Nanton M, Griffin A, McSorley SJ Culling of activated CD4 T cells during typhoid is driven by Salmonella virulence genes J Immunol,
  • Link Icon 2009 Griffin A, Baraho-Hassan D, McSorley SJ Successful treatment of bacterial infection hinders development of acquired immunity J Immunol,
  • Link Icon 2008 Jerke+S,+Srinivasan+A,+McSorley+SJ Expression+of+Toll/IL-1R+domain-containing+adaptor+protein+(TIRAP)+is+detrimental+to+primary+clearance+of+Salmonella+and+is+not+required+for+the+generation+of+protective+immunity Immunol+Lett,

Most Recent 5 Book Chapters

2009 Moon JJ, McSorley SJ: Tracking the dynamics of salmonella specific T cell responses, , Curr Top Microbiol Immunol. 179-98.