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Photo: Stephen J Mcsorley

Stephen J Mcsorley- BSc, PhD
Professor in Residence
Anatomy, Physiology & Cell Biology
Center for Comparative Medicine

County Rd 98 at Hutchison Drive
Davis, CA 95616

+1 530 752 3414
sjmcsorley@ucdavis.edu

   

Research Focus

My research focuses on the innate and adaptive immune response to bacterial pathogens and largely uses mouse models of infection with Salmonella and Chlamydia.

Specialty Focus

Immunology and Microbiology

Education

1992 B.Sc. Immunology, Glasgow University, Glasgow, Scotland
1996 Ph.D. Immunology, Glasgow University, Glasgow, Scotland

Honors and Awards

1998-2001 Irvington Institute of Immunology Fellow
1995-1996 Federation Pour La Recherche Medicale Postdoctoral Fellowship

Active Research Grants

Principal Investigator, Innate immune response to bacterial flagellins, (Principal Investigator), NIH/NIAID

Principal Investigator, Protective immunity against typhoid, (Principal Investigator), NIH/NIAID

Principal Investigator, Generation of a TCR transgenic mouse to study Chlamydia genital tract infection, (Principal Investigator), NIH/NIAID

Co-Investigator, Functional Plasticity in the Helicobacter Pylori Type IV Secretion System, Jay Solnick (Principal Investigator), NIH/NIAID

Principal Investigator, CD4 T cell Responses to Chlamydia Infection, (Principal Investigator), NIH/NIAID

Most Recent 10 Publications

  • Stephen J Mcsorley: A Protective Vaccine against Chlamydia Genital Infection Using Vault Nanoparticles without an Added Adjuvant. 2017 Jiang, J, Liu, G, Kickhoefer, VA, Rome, LH, Li, LX, McSorley, SJ, Kelly, KA A Protective Vaccine against Chlamydia Genital Infection Using Vault Nanoparticles without an Added Adjuvant. Vaccines,
  • Stephen J Mcsorley: U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice. 2017 Risso, GS, Carabajal, MV, Bruno, LA, Ibañez, AE, Coria, LM, Pasquevich, KA, Lee, SJ, McSorley, SJ, Briones, G, Cassataro, J U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice. Frontiers in immunology,
  • Stephen J Mcsorley: Absence of TLR11 does not confer susceptibility to Salmonella Typhi 2016 Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Baumler AJ, Pier GB, Galán JE, Yarovinsky F Absence of TLR11 does not confer susceptibility to Salmonella Typhi Cell,
  • Stephen J Mcsorley: Collateral Damage: Detrimental Effect of Antibiotics on the Development of Protective Immune Memory. 2016 Benoun, JM, Labuda, JC, McSorley, SJ Collateral Damage: Detrimental Effect of Antibiotics on the Development of Protective Immune Memory. mBio,
  • Stephen J Mcsorley: NOD1 and NOD2 signalling links ER stress with inflammation. 2016 Keestra-Gounder, AM, Byndloss, MX, Seyffert, N, Young, BM, Chávez-Arroyo, A, Tsai, AY, Cevallos, SA, Winter, MG, Pham, OH, Tiffany, CR, de Jong, MF, Kerrinnes, T, Ravindran, R, Luciw, PA, McSorley, SJ, Bäumler, AJ, Tsolis, RM NOD1 and NOD2 signalling links ER stress with inflammation. Nature,
  • Stephen J Mcsorley: Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens. 2016 Li, LX, Benoun, JM, Weiskopf, K, Garcia, KC, McSorley, SJ Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens. Infection and immunity,
  • Stephen J Mcsorley: Adhesion Molecules Associated with Female Genital Tract Infection. 2016 Qualai, J, Cantero, J, Li, LX, Carrascosa, JM, Cabré, E, Dern, O, Sumoy, L, Requena, G, McSorley, SJ, Genescà, M Adhesion Molecules Associated with Female Genital Tract Infection. PloS one,
  • Stephen J Mcsorley: Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential. 2016 Qualai, J, Li, LX, Cantero, J, Tarrats, A, Fernández, MA, Sumoy, L, Rodolosse, A, McSorley, SJ, Genescà, M Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential. PloS one,
  • Stephen J Mcsorley: Contaminated water delivery as a simple and effective means of experimental Salmonella infection 2015 O’Donnell H, Pham O, Benoun J, Ravesloot-Chavez MM, McSorley SJ Contaminated water delivery as a simple and effective means of experimental Salmonella infection Future Microbiol.,
  • Stephen J Mcsorley: Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria 2015 Mooney JP, Lee SJ, Lokken KL, Nanton MR, Nuccio SP, McSorley SJ, Tsolis RM Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria PLoS Neglected Tropical Diseases,

Most Recent 5 Book Chapters

2012 Atif SM, McSorley SJ: TLR5, Choi S, (ed), Encyclopedia of Signaling Molecules, New York. 1875-1881.

2009 Moon JJ, McSorley SJ: Tracking the dynamics of salmonella specific T cell responses, , Curr Top Microbiol Immunol. 179-98.

1998 McSorley SJ, Liew FYI: Leishmaniasis, Delves PJ, (ed), Encyclopedia of Immunology (Second Edition). 1546–1551.

1998 McSorley SJ, F Liew Y: Nitric Oxide, Delves PJ, (ed), Encyclopedia of Immunology (Second Edition). 1859–1861.