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Photo: Kevin Douglas Woolard

Kevin Douglas Woolard- DVM, PhD
Assistant Professor
Pathology, Microbiology & Immunology

4323 VM3A
Davis, CA 95616

+1 530 752 2235
kdwoolard@ucdavis.edu

   

Research Focus

Comparative glioma biology, cancer stem cells, neural stem cells.

Specialty Focus

Neuro-oncology, neuropathology, surgical oncology

Education

1999 Biochemistry; Animal Science; Physics, North Carolina State University, Raleigh, North Carolina
2003 DVM , North Carolina State University, Raleigh, NC
2011 PhD Cell Biology, North Carolina State University, Raleigh, NC

Honors and Awards

2010 NIH Nominee for Burroughs Welcome Fund Career Award for Medical Scientists
2009 Canine Health Foundation Young Cancer Investigator’s Award for Basic Science
2009 Second Place, Merck-Merial National Veterinary Scholars Symposium Young Investigator Award
2008 Dr. Monica Menard Award For Excellence in Veterinary, Pathobiological Research, North Carolina State University, College of Veterinary Medicine
2006 CL Davis Foundation Student Scholarship Award in Comparative Pathology
2003 Pfizer Award for Outstanding Student in Veterinary Internal Medicine
2003 Award for Outstanding Service in Veterinary Oncology, North Carolina State University, College of Veterinary Medicine
1998 Phi Kappa Phi, North Carolina State University
1998 Phi Beta Kappa, North Carolina State University

Licenses

Board Certification in Veterinary Anatomic Pathology

Active Research Grants

Principal Investigator, Molecular Mechanisms of Neurodegeneration in Canine Degenerative Myelopathy, (Principal Investigator), Center for Companion Animal Health, UC Davis

Principal Investigator, Prognostic Significance of Epithelial-Mesenchymal Transition in Canine Oral Melanoma, (Principal Investigator), Center for Companion Animal Health, UC Davis

Co-Principal Investigator, Investigation of Tyrosinase Expression in Canine Melanoma, Kent (Principal Investigator), Center for Companion Animal Health, UC Davis

Principal Investigator, Contributions of disseminated glioma stem cells to tumor recurrence., (Principal Investigator), Elsa U. Pardee Foundation

Most Recent 10 Publications

  • Kevin Douglas Woolard: Characterization of the temporomandibular joint of the harbour porpoise (Phocoena phocoena) and Risso's dolphin (Grampus griseus) 2015 McDonald M, Vapniarsky-Arzi N, Verstraete FJ, Staszyk C, Leale DM, Woolard KD, Arzi B Characterization of the temporomandibular joint of the harbour porpoise (Phocoena phocoena) and Risso's dolphin (Grampus griseus) Arch Oral Biol,
  • Kevin Douglas Woolard: The raccoon polyomavirus genome and tumor antigen transcription are stable and abundant in neuroglial tumors 2014 Brostoff T, Dela Cruz FN, Church ME, Woolard KD, Pesavento PA The raccoon polyomavirus genome and tumor antigen transcription are stable and abundant in neuroglial tumors Journal of virology,
  • Kevin Douglas Woolard: Identification of molecular pathways facilitating glioma cell invasion in situ. 2014 Nevo I, Woolard K, Cam M, Li A, Webster JD, Kotliarov Y, Kim HS, Ahn S, Walling J, Kotliarova S, Belova G, Song H, Bailey R, Zhang W, Fine HA Identification of molecular pathways facilitating glioma cell invasion in situ. PloS one,
  • Kevin Douglas Woolard: Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells 2014 Baysan M, Woolard K, Bozdag S, Riddick G, Kotliarova S, Cam MC, Belova GI, Ahn S, Zhang W, Song H, Walling J, Stevenson H, Meltzer P, Fine HA Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells PloS one,
  • Kevin Douglas Woolard: ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State. 2014 Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray MA, Gopal S, Theisen MA, Bilodeau S, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Woolard K, Lee J, Nishimura R, Sakata N, Fine HA, Carpenter AE, Silver SJ, Verhaak RG, Califano A, Young RA, Ligon KL, Mellinghoff IK, Root DE, Sabatini DM, Hahn WC, Chheda MG ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State. Cell Rep,
  • Kevin Douglas Woolard: Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear
Stabilization 2012 Ene CI, Edwards L, Riddick G, Baysan M, Woolard K, Kotilarova S, Cam M, Walling J, Zhou M, Stevenson H, Mazur S, Kim HS, Killian K, Veenstra T, Appella E, Bailey R, Song H, Zhang W, Fine HA Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear Stabilization PLoS One,
  • Kevin Douglas Woolard: Gliomagenesis arising from Pten and Ink4a/Arf deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc 2012 Kim HS, Woolard K, Lai C, Bauer PO, Lee J, Li A, Song H, Zhang W, Fine HA Gliomagenesis arising from Pten and Ink4a/Arf deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc Cancer Res,
  • Kevin Douglas Woolard: Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioblastoma 2012 Morgan R, Johnson LA, Davis JA, Woolard K, Zheng Z, Feldman SA, Kuan CT, Nachimuthu C, Burns WR, Frankel TL, Fine HA, Rosenberg SA Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioblastoma Human Gene Therapy,
  • Kevin Douglas Woolard: Effect of Brain- and Tumor-Derived Connective Tissue Growth Factor on Glioma Invasion 2011 Edwards LA, Woolard K, Son MJ, Li A, Lee H, Ene C, Mantey C, Maric D, Song H, Jensen R, Zhang W, Fine HA Effect of Brain- and Tumor-Derived Connective Tissue Growth Factor on Glioma Invasion J Natl Cancer Inst,
  • Kevin Douglas Woolard: Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients 2009 Wei BR, Hoover SB, Ross MM, Zhou W, Meani F, Edwards JB, Spehalski EI, Risinger JI, Alvord WG, Quiñones OA, Belluco C, Martella L, Campagnutta E, Ravaggi A, Dai RM, Goldsmith PK, Woolard KD, Pecorelli S, Liotta LA, Petricoin EF, Simpson RM Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients PLoS One,