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Photo: Carrie Finno

Carrie Finno
Assistant Professor and Researcher
Population Health & Reproduction

280 CCAH
Davis, CA 95616

+1 530 752 2739
cjfinno@ucdavis.edu

   

Research Focus

My laboratory investigates the molecular basis for genetic diseases in the horse and other companion animals. One of the translational focuses of my research is to investigate the role of vitamin E in neurodegeneration, using a well-established mouse model and a naturally-occurring model of neuroaxonal dystrophy in the horse (eNAD).

Specialty Focus

As a diplomate of the American College of Veterinary Internal Medicine, I have a specialty focus on equine internal medicine. Specifically, my laboratory investigates the genetic basis of neurodegenerative diseases in animal models.

Education

1999 BSc Biology, Emory University, Atlanta, GA
2004 DVM Veterinary Medicine, University of Minnesota, College of Veterinary Medicine, St Paul, MN
2006 Internship Large Animal Medicine and Surgery, University of Minnesota, College of Veterinary Medicine, St Paul, MN
2008 Residency Large Animal Internal Medicine, University of California, Davis, VMTH, Davis, CA
2012 PhD Comparative Pathology, University of California, Davis, Davis, CA
2013 Post-Doctorate , University of Minnesota, St. Paul, MN

Licenses

Diplomate, American College of Veterinary Internal Medicine
Licensure, Minnesota

Active Research Grants

Principal Investigator, Molecular pathogenesis of alpha-tocopherol associated neuroaxonal dystrophy in animal models, (Principal Investigator), National Institute of Health

Principal Investigator, Unraveling complex traits by defining genome function (Part I), (Principal Investigator), Grayson-Jockey Club Research Foundation

Co-Investigator, The effect of alpha-tocopherol supplementation on vitamin E metabolism in healthy horses and horses with neuroaxonal dystrophy, Puschner (Principal Investigator), UC Davis Center for Equine Health

Principal Investigator, Genetic Investigation of occipitoatlantoaxial malformation (OAAM) in Arabian Horses, (Principal Investigator), Arabian Horse Association

Principal Investigator, Secrets in the bones: how functional genomics will broaden our understanding of catastrophic breakdown in racehorses, (Principal Investigator), Priority Partnership Collaboration Award: University of Sydney and UC Davis

Principal Investigator, Validation of putative genetic variants for equine neuroaxonal dystrophy, (Principal Investigator), Center for Equine Health, UC Davis

Principal Investigator, Validation of putative genetic variants for juvenile idiopathic epilepsy in Arabian horses, (Principal Investigator), Center for Equine Health, UC Davis

Co-Investigator, Genetic investigation of idiopathic persistent hypocalcemia in the Thoroughbred, Magdesian (Principal Investigator), Center for Equine Health, UC Davis

Most Recent 10 Publications

  • Carrie Finno: Developing a 670k genotyping array to tag ~2M SNPs across 24 horse breeds 2017 Schaefer RJ, Schubert M, Bailey E, Bannasch DL, Barrey E, Bar-Gal GK, Brem G, Brooks SA, Distl O, Fries R, Finno CJ, Gerber V, Haase B, Jagannathan V, Kalbfleisch T, Leeb T, Lindgren G, Lopes MS, Mach N, da C├ómara Machado A, MacLeod JN, McCoy A, Metzger J, Penedo C, Polani S, Rieder S, Tammen I, Tetens J, Thaller G, Verini-Supplizi A, Wade CM, Wallner B, Orlando L, Mickelson JR, McCue ME Developing a 670k genotyping array to tag ~2M SNPs across 24 horse breeds BMC Genomics ,
  • Carrie Finno: Identification of long non-coding RNA in the horse transcriptome 2017 Scott EY, Mansour TA, Bellone RR, Brown T, Mienaltowski M, Penedo MC, Ross PJ, Valberg SJ, Murray JD, Finno CJ Identification of long non-coding RNA in the horse transcriptome BMC Genomics,
  • Carrie Finno: Pigment retinopathy in warmblood horses with equine degenerative myeloencephalopathy and equine motor neuron disease 2017 Finno CJ, Kaese HJ, Miller AD, Gianino G, Divers T, Valberg SJ. Pigment retinopathy in warmblood horses with equine degenerative myeloencephalopathy and equine motor neuron disease Vet Ophthalmol,
  • Carrie Finno: Tissue resolved, gene structure refined equine transcriptome 2017 Mansour TA, Scott EY, Finno CJ, Bellone RR, Mienaltowski M, Penedo MC, Ross PJ, Valberg SJ, Murray JD, Brown CT Tissue resolved, gene structure refined equine transcriptome BMC Genomics,
  • Carrie Finno: Deletion of 2.7 kb near HOXD3 in an Arabian horse with
occipitoatlantoaxial malformation 2017 Bordbari M, Penedo MCT, Aleman M, Valberg SJ, Mickelson J, Finno CJ Deletion of 2.7 kb near HOXD3 in an Arabian horse with occipitoatlantoaxial malformation Anim Genet,
  • Carrie Finno: Defining trends in global gene expression in Arabian horses with Cerebellar Abiotrophy 2017 Scott EY, Penedo MCT, Murray JD, Finno CJ Defining trends in global gene expression in Arabian horses with Cerebellar Abiotrophy Cerebellum,
  • Carrie Finno: Transcriptome profiling of equine vitamin E deficient neuroaxonal dystrophy identifies upregulation of liver X receptor target genes 2016 Finno CJ, Bordbari M, Valberg SJ, Lee D, Herron J, Hines K, Monsour T, Scott E, Bannasch DL, Mickelson J, Xu L Transcriptome profiling of equine vitamin E deficient neuroaxonal dystrophy identifies upregulation of liver X receptor target genes Free Rad Mol Biol,
  • Carrie Finno: GO-FAANG meeting; a gathering on functional annotation of animal genomes 2016 Tuggle CK, Giuffra E, White SN, Clarke L, Zhou H, Ross PJ, Acloque H, Reecy JM, Archibald A, Bellone RB, Boichard M, Chamberlain A, Cheng H, Crooijmans R, Delany ME, Finno CJ, Groenen MA, Hayes B, Lunney JK, Petersen JL, Plastow GS, Schmidt CJ, Song J, Watson M. GO-FAANG meeting; a gathering on functional annotation of animal genomes Anim Genet,
  • Carrie Finno: Suspected myofibrillar myopathy in Arabian horses with a history of exertional rhabdomyolysis 2016 Valberg SJ, McKenzie EC, Eyrich LV, Shivers J, Barnes NE, Finno CJ Suspected myofibrillar myopathy in Arabian horses with a history of exertional rhabdomyolysis Equine Vet J,
  • Carrie Finno: Major histocompatibility complex I and II expression and lymphocytic subtypes in muscle of horses with immune-mediated myositis. 2016 Durward-Akhurst S, Finno CJ, Barnes N, Shivers J, Guo LT, Shelton GD, Valberg SJ. Major histocompatibility complex I and II expression and lymphocytic subtypes in muscle of horses with immune-mediated myositis. J Vet Intern Med,

Most Recent 5 Book Chapters

2017 Finno CJ: Vitamin and mineral assessment, Pusterla N, Higgins R, (ed), Interpretation of Equine Laboratory Diagnostics (Chapter 13), Hoboken, NJ. .

2017 Finno CJ: Equine genetic testing, Pusterla N, Higgins R, (ed), Interpretation of Equine Laboratory Diagnostics (Chapter 52), Hoboken, NJ. .

2015 Finno CJ: Chapter 89: Equine neuroaxonal dystrophy, Sprayberry KA, Robinson NE, (ed), Robinson's Current Therapy in Equine Medicine, 7th Edition, St. Louis, MO. .

2015 Finno CJ, Bannasch DL: Chapter 52: Genetic tests for large animals, Smith BP, (ed), Large Animal Internal Medicine, 5th edition, St. Louis, MO. 1530-7.

2014 Haskell SRR, Loghry BL, Finno CJ, Wegner K, DeFazio J, Gilsenan W, Johnson AL: Chapter 4: Physical exam, Lien L, Loly S, Ferguson S, (ed), Large Animal Medicine for the Veterinary Technician, 1st edition. .