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Photo: Jeroen Saeij

Jeroen Saeij
Associate Professor and Researcher
Pathology, Microbiology & Immunology

3325 VM3A
Davis, CA 95616

+1 530 752 1401
jsaeij@ucdavis.edu

   

Specialty Focus

Genetics, Genomics, Parasitology, Immunology, Biochemistry, Bioinformatics, Molecular Biology, Human Disease, Animal Disease.

Education

1995 B.Sc. Bioprocess Technology, Wageningen University, Wageningen, The Netherlands
1997 M.Sc. Bioprocess Technology, Wageningen University, Wageningen, The Netherlands
2002 Ph.D. Cell Biology and Immunology, Wageningen University, Wageningen, The Netherlands

Active Research Grants

Principal Investigator, Genetic analysis of innate immunity to infection, (Principal Investigator), The Pew Scholars Program

Principal Investigator, Inhibiting Toxoplasma growth by disrupting its access to host small molecules, (Principal Investigator), National Institutes of Health

Principal Investigator, A serological test to determine strains associated with ocular toxoplasmosis, (Principal Investigator), National Institutes of Health

Principal Investigator, Toxoplasma proteins that modulate the host cell, (Principal Investigator), National Institutes of Health

Most Recent 10 Publications

  • Jeroen Saeij: Toxoplasma gondii superinfection and virulence during secondary infection correlates with the exact ROP5/ROP18 allelic combination 2015 Jensen KD, Camejo A, Melo MB, Cordeiro C, Grotenbreg GM, Frickel E, Ploegh HL, Young L, Saeij JP Toxoplasma gondii superinfection and virulence during secondary infection correlates with the exact ROP5/ROP18 allelic combination MBio,
  • Jeroen Saeij: The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole. 2015 Gold, DA, Kaplan, AD, Lis, A, Bett, GC, Rosowski, EE, Cirelli, KM, Bougdour, A, Sidik, SM, Beck, JR, Lourido, S, Egea, PF, Bradley, PJ, Hakimi, MA, Rasmusson, RL, Saeij, JP The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole. Cell host & microbe,
  • Jeroen Saeij: Transcriptional and Linkage Analyses Identify Loci that Mediate the Differential Macrophage Response to Inflammatory Stimuli and Infection. 2015 Hassan, MA, Jensen, KD, Butty, V, Hu, K, Boedec, E, Prins, P, Saeij, JP Transcriptional and Linkage Analyses Identify Loci that Mediate the Differential Macrophage Response to Inflammatory Stimuli and Infection. PLoS genetics,
  • Jeroen Saeij: Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits 2014 Hassan MA, Saeij JP Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits Bioessays,
  • Jeroen Saeij: Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines 2014 Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines Immunity,
  • Jeroen Saeij: Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii 2014 Cirelli KM, Gorfu G, Hassan MA, Printz M, Crown D, Breen L, Leppla SH, Grigg ME, Saeij JP, Moayeri M Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii PLoS Pathogens,
  • Jeroen Saeij: miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain 2014 Cannella D, Brenier-Pinchart MP, Braun L, van Rooyen JM, Bougdour A, Bastien O, Behnke MS, Curt RL, Curt A, Saeij JP, Sibley LD, Pelloux H, Hakimi MA miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain Cell Rep.,
  • Jeroen Saeij: A dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii 2014 Gorfu G, Cirelli KM, Melo MB, Mayer-Barber K, Crown D, Koller BH, Masters S, Sher A, Leppla SH, Moayeri M, Saeij JP, Grigg ME A dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii MBio,
  • Jeroen Saeij: The genetic basis for individual differences in mRNA splicing and Apobec1 editing activity in murine macrophages 2014 Hassan MA, Butty V, Jensen KD, Saeij JP The genetic basis for individual differences in mRNA splicing and Apobec1 editing activity in murine macrophages Genome Research,
  • Jeroen Saeij: Toxoplasma gondii inhibits gamma interferon (IFN-?)- and IFN-ß-induced host cell STAT1 transcriptional activity by increasing the association of STAT1 with DNA 2014 Rosowski EE, Nguyen QP, Camejo A, Spooner E, Saeij JP Toxoplasma gondii inhibits gamma interferon (IFN-?)- and IFN-ß-induced host cell STAT1 transcriptional activity by increasing the association of STAT1 with DNA Infection and Immunity,

Most Recent 5 Book Chapters

2002 Verburg-van Kemenade BML, Engelsma MY, Huising MO, Kwang J, van Muiswinkel WB, Saeij JP, Metz JR, Flik G: Crosstalk between the neuro-endocrine and immune system in teleosts, , In: Perspective in Comparative Endocrinology: Unity and Diversity. 359-367.