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Photo: Jeroen Saeij

Jeroen Saeij
Associate Professor and Researcher
Pathology, Microbiology & Immunology

3325 VM3A
Davis, CA 95616

+1 530 752 1401
jsaeij@ucdavis.edu

   

Specialty Focus

Genetics, Genomics, Parasitology, Immunology, Biochemistry, Bioinformatics, Molecular Biology, Human Disease, Animal Disease.

Education

1995 B.Sc. Bioprocess Technology, Wageningen University, Wageningen, The Netherlands
1997 M.Sc. Bioprocess Technology, Wageningen University, Wageningen, The Netherlands
2002 Ph.D. Cell Biology and Immunology, Wageningen University, Wageningen, The Netherlands

Active Research Grants

Principal Investigator, Inhibiting Toxoplasma growth by disrupting its access to host small molecules, (Principal Investigator), National Institutes of Health

Principal Investigator, A serological test to determine strains associated with ocular toxoplasmosis, (Principal Investigator), National Institutes of Health

Principal Investigator, Toxoplasma proteins that modulate the host cell, (Principal Investigator), National Institutes of Health

Principal Investigator, Cats protect cats: a Toxoplasma vaccine for cats, made by cats, (Principal Investigator), Center for Companion Animal Health

Most Recent 10 Publications

  • Jeroen Saeij: A Genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes 2016 Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS, Thiru P, Saeij JP, Carruthers VB, Niles JC, Lourido S A Genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes Cell,
  • Jeroen Saeij: Early interactions of murine macrophages with Francisella tularensis map to mouse chromosome 19 2016 Fink A, Hassan MA, Okan NA, Sheffer M, Camejo A, Saeij JP, Kasper DL Early interactions of murine macrophages with Francisella tularensis map to mouse chromosome 19 mBio,
  • Jeroen Saeij: Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes 2016 Lorenzi H, Khan A, Behnke MS, Namasivayam S, Swapna LS, Hadjithomas M, Karamycheva S, Pinney D, Brunk BP, Ajioka JW, Ajzenberg D, Boothroyd JC, Boyle JP, Dardé ML, Diaz-Miranda MA, Dubey JP, Fritz HM, Gennari SM, Gregory BD, Kim K, Saeij JP, Su C, White MW, Zhu XQ, Howe DK, Rosenthal BM, Grigg ME, Parkinson J, Liu L, Kissinger JC, Roos DS, Sibley LD Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes Nature Communications,
  • Jeroen Saeij: Transcriptional and linkage analyses identify loci that mediate the differential macrophage response to inflammatory stimuli and infection 2015 Hassan MA, Jensen KD, Butty V, Hu K, Boedec E, Prins P, Saeij JP Transcriptional and linkage analyses identify loci that mediate the differential macrophage response to inflammatory stimuli and infection PLoS Genetics,
  • Jeroen Saeij: The toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole 2015 Gold DA, Kaplan AD, Lis A, Bett GC, Rosowski EE, Cirelli KM, Bougdour A, Sidik SM, Beck JR, Lourido S, Egea PF, Bradley PJ, Hakimi MA, Rasmusson RL, Saeij JP The toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole Cell Host & Microbe,
  • Jeroen Saeij: Toxoplasma gondii superinfection and virulence during secondary infection correlates with the exact ROP5/ROP18 allelic combination 2015 Jensen KD, Camejo A, Melo MB, Cordeiro C, Grotenbreg GM, Frickel E, Ploegh HL, Young L, Saeij JP Toxoplasma gondii superinfection and virulence during secondary infection correlates with the exact ROP5/ROP18 allelic combination MBio,
  • Jeroen Saeij: Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits 2014 Hassan MA, Saeij JP Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits Bioessays,
  • Jeroen Saeij: Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines 2014 Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines Immunity,
  • Jeroen Saeij: Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii 2014 Cirelli KM, Gorfu G, Hassan MA, Printz M, Crown D, Breen L, Leppla SH, Grigg ME, Saeij JP, Moayeri M Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii PLoS Pathog,
  • Jeroen Saeij: miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain 2014 Cannella D, Brenier-Pinchart MP, Braun L, van Rooyen JM, Bougdour A, Bastien O, Behnke MS, Curt RL, Curt A, Saeij JP, Sibley LD, Pelloux H, Hakimi MA miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain Cell Rep.,

Most Recent 5 Book Chapters

2002 Verburg-van Kemenade BML, Engelsma MY, Huising MO, Kwang J, van Muiswinkel WB, Saeij JP, Metz JR, Flik G: Crosstalk between the neuro-endocrine and immune system in teleosts, Goos HJ Th [and others], (ed), Perspective in Comparative Endocrinology: Unity and Diversity, Bologna, Italy. 359-67.