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Photo: Bruno H Pypendop

Bruno H Pypendop- DrMedVet, DrVetSci
Professor
Surgical & Radiological Sciences

1114B Tupper Hall
Davis, CA 95616

+1 530 752 7474
bhpypendop@ucdavis.edu

   

Research Focus

Clinical pharmacology of anesthetic and analgesic agents in animal species, with an emphasis on cats.

Specialty Focus

Veterinary anesthesiology

Education

1999 DrVetSci Clinical pharmacology, University of Liege, Liege, Belgium
1992 DrMedVet Veterinary Medicine, University of Liege, Liege, Belgium
1989 Candidate Vet Sci Veterinary Science, Catholic University of Louvain, Louvain-la-Neuve, Belgium

Honors and Awards

2002 Myrtle L. Oliver Memorial Resident Research Award
2001 Surgivet/Anesco Award, ACVA annual meeting, New Orleans, October 2001 “Hemodynamic effects of nitrous oxide in isoflurane-anesthetized cats”
1992 Prix des Annales de Médecine Vétérinaire, Liege, Belgium ”Sedation and skin testing in the dog”

Licenses

Diplomate American College of Veterinary Anesthesiologists

Active Research Grants

Co-Principal Investigator, Novel analgesic for cats with inflammatory pain, Alonso Guedes (Principal Investigator), Winn Feline Foundation (Miller Trust) and Center for Companion Animal Health

Principal Investigator, MK-467 in combination with dexmedetomidine in cats: a dose-finding and pharmacokinetic study, (Principal Investigator), Morris Animal Foundation

Principal Investigator, Antihyperalgesic effects of amantadine in cats, (Principal Investigator), Center for Companion Animal Health/San Francisco Foundation

Principal Investigator, Hemodynamic effects of MK-467 in combination with dexmedetomidine in cats, (Principal Investigator), Winn Feline Foundation and Center for Companion Animal Health

Most Recent 10 Publications

  • Link Icon 2014 Pypendop, BH, Ilkiw, JE Relationship between plasma dexmedetomidine concentration and sedation score and thermal threshold in cats. American journal of veterinary research,
  • Link Icon 2014 Pypendop, BH, Ilkiw, JE Pharmacokinetics of dexmedetomidine after intravenous administration of a bolus to cats. American journal of veterinary research,
  • Link Icon 2014 Pypendop, BH, Ilkiw, JE, Shilo-Benjamini, Y Bioavailability of morphine, methadone, hydromorphone, and oxymorphone following buccal administration in cats. Journal of veterinary pharmacology and therapeutics,
  • Link Icon 2014 Kelly, KR, Pypendop, BH, Christe, KL Pharmacokinetics of buprenorphine following intravenous and intramuscular administration in male rhesus macaques (Macaca mulatta). Journal of veterinary pharmacology and therapeutics,
  • Link Icon 2014 Pypendop, BH, Brosnan, RJ, Majewski-Tiedeken, CR, Stanley, SD, Ilkiw, JE Pharmacokinetics of fentanyl, alfentanil, and sufentanil in isoflurane-anesthetized cats. Journal of veterinary pharmacology and therapeutics,
  • Link Icon 2014 Hedges, AR, Pypendop, BH, Shilo, Y, Stanley, SD, Ilkiw, JE Impact of the blood sampling site on time-concentration drug profiles following intravenous or buccal drug administration. Journal of veterinary pharmacology and therapeutics,
  • Link Icon 2014 Ovbey, DH, Wilson, DV, Bednarski, RM, Hauptman, JG, Stanley, BJ, Radlinsky, MG, Larenza, MP, Pypendop, BH, Rezende, ML Prevalence and risk factors for canine post-anesthetic aspiration pneumonia (1999-2009): a multicenter study. Veterinary anaesthesia and analgesia,
  • Link Icon 2013 Pypendop BH, Escobar A, Siao KT, Stanley SD, Ilkiw JE Effect of dexmedetomidine on its clearance: a pharmacokinetic model. J Vet Pharmacol Ther,
  • Link Icon 2013 Brosnan RJ, Pypendop BH, Majewski-Tiedeken CR, Shilo-Benjamini Y, Ilkiw JE Naltrexone does not affect isoflurane minimum alveolar concentration in cats. Vet Anaesth Analg,
  • Link Icon 2012 Phair KA, Larsen RS, Wack RF, Shilo-Benjamini Y, Pypendop BH Determination of the minimum anesthetic concentration of sevoflurane in thick-billed parrots (Rhynchopsitta pachyrhyncha). Am J Vet Res,

Most Recent 5 Book Chapters

2011 Pypendop BH: Anesthesia in the patient with cardiac disease, Cote E, Sleeper M, Meurs K, Macdonald K, (ed), Feline Cardiology, Ames. 411-21.

2011 Pypendop BH, Ilkiw JE: Anesthesia and Perioperative Care, Little S, (ed), The Cat, Clinical Medicine and Management, Philadelphia. 112-50.

2008 Pypendop BH, Barter LS: Pharmacologic management of pain for patients with neurologic disease, Dewey CW, (ed), A Practical Guide to Canine and Feline Neurology. 2nd Edition, Ames, Iowa. 585-98.

2006 Pypendop BH: Jet ventilation, Hopper K, Silverstein DC, (ed), Handbook of Small Animal Emergency and Critical Care, St Louis. 910-12.

2006 Pypendop BH: Capnography, Hopper K, Silverstein DC, (ed), Handbook of Small Animal Emergency and Critical Care, St Louis. 875-7.