Martin Schmuck

Martin Schmuck

Post Doctoral Scholar

Hometown

Wuerzburg, Germany

Education

From 2006 to 2011 I studied chemistry at the Ruprecht-Karls-University Heidelberg in Germany, with main focus on imaging and analytical techniques. In 2011 I obtained my masters degree at the Max Planck institute for biophysical chemistry in the group of Prof. Stefan Hell in Goettingen.

I performed my PhD thesis from 2012 to 2015 in the group of Prof. Ellen Fritsche at the Leibniz Research Institute for Environmental Medicine (IUF) in Duesseldorf, Germany . The main topic of my PhD thesis was the development of a high content image analysis (HCA) screening workflow for the three dimensional ‘Neurosphere Assay’ to improve human risk assessment. The software was designed to extract important neurodevelopmental endpoints, mimicked by the Neurosphere Assay, such as neuronal and oligodendrocyte identification, analysis of neuronal morphology, radial cell migrationand distribution of cell types within the formed migration area. During my postdoctoral position in 2016 at the Leibniz Research Institute for Environmental Medicine I was head of the high content imaging facility and coordinated image analyses projects of a wide variety of different in vitro screening applications.

In January 2016 I started my postdoctoral fellowship in the group at Pamela Pam J. Lein. Within this fellowship, software is supposed to be developed which on the one hand is capable to automate manual analysis steps and on the other hand to include new algorithms which are able to improve accuracy and precision of endpoint assessment as well as to add new algorithms for extraction of novel endpoints. Application fields for the new software include a variety of systems, such as in vitro cell culture systems, zebrafish, tissue sections and MRI images.