I. Literature Review
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Marine mammals are known to contract and carry many known zoonotic diseases.
1
2
Until recently human contact with these animals has been limited to whalers,
fisherman, and indigenous peoples who hunt these animals for food.
3
Since the Marine Mammal Act was enacted in 1972 contact between
sea mammals and humans has increased.
1
Efforts to rescue and rehabilitate sick and injured marine mammals
have included the establishment of more wildlife rehabilitation centers and
aquaria in the United States. In
addition to biologist, trainers and veterinarians, many of these facilities
are staffed by volunteers, placing a larger population at the potential risk
for zoonoses.
Also at risk are the growing number of tourist who participate
in the swim-with-dolphins programs that are offered in coastal waters around
the world. Some of these programs allow participants to swim with wild dolphins,
of which the health status is unknown.
4
5
The health of the participants may also play a role in the risk of disease
transmission for many of these programs are targeted to people with life
threatening or debilitating diseases, like cancer.
6
Spekkfinger or blubber finger is one of the earliest documented zoonotic
diseases transmissible to humans by marine mammals. While the causative agent
has been reported as Staphylococcus
or Erysipelothrix it is now believed
to be caused by Mycoplamsa spp.
This disease has historically been an affliction of whalers and fishermen,
but recent reports of trainers and handlers contracting the skin and joint
infection has appear in the literature.
This disease appears to result most often from bites.
3
Sealpox, a parapox virus, Mycobacterium
murium, Erysipelothrix rhusiopathiae, and
Staphylococcus aureus are other documented organisms causing concurrent
infections of trainers, caretakers and the animals.
7
8
9
Two of three seal handlers working with Grey Seals (
Halichoerus grypus) developed raised caseous nodules on their hands,
after working with the animals during an energetics study conducted in 1983.
The agent that was isolated from both the handlers and the seals
was identified as a parapox virus commonly refered to as sealpox.
10
In 1974, four students acquired an
E. rhusiopathiae infection from the carcass of a stranded pilot whale
(Globicephala melas).
The organism was isolated from both the lesions on the hands of
the students and the tissues from the whale collected at necropsy.
9
While in 1970, a long term
M. murium infection was acquired by a trainer from the bite from a dolphin.
8
However, the S. aureus
infections seen in 8 dolphins (Tursiops
truncatus) and 14 oceanarium personnel in 1976, was determined by the
researcher to not have been cross infections from either dolphin to trainer
or trainer to dolphin. 7
Some more serious diseases have also been recorded in the literature, including
Brucella spp. Leptospira spp., Mycobacterium
bovis, and Influenza virus A.
3
11
12
13
14
However, documentation of humans actually acquiring these diseases
from direct contact with marine mammals is lacking in some cases.
Foster reported the isolation of
Brucella spp. from many different species of marine mammals.
These organisms were isolated from subcutaneous lesions, spleen
and lymph nodes.13
At this time the infective potential of the
Brucella spp. isolated was not yet known.
However, Brew reports that a researcher working with isolates of
Brucella from marine mammals
tested positive for strains of Brucella identical to those reported in the
Foster study. Based on this incident,
the suggestion is made that those who come in contact with marine mammals
are at risk for acquiring the disease.
12
Three workers conducting necropsies on sea lions (
Zalophus californianus californianus) in 1978, became ill, and developed
serum agglutinating titers to Leptospira
pomona. Persons who are in contact
with bodily fluid of seal lions, particularly urine and urine contaminated
water are at risk for contracting this disease.
11
After the death of three seals (
Arctocephalus forsteri) in 1986 a seal trainer developed a pulmonary
tuberculosis; the isolate of M.bovis
from the seals and the seal trainer were reported as identical.
The barking and coughing behavior of seals and sea lions provides
enough opportunity for aerosol transmission; trainers do not need to be in
direct contact with contagious animals.
14
Influenza A is also reported as a disease with aerosol transmission.
The ecology of this virus appears to be complex involving birds,
humans and other terrestrial mammals.
3,15
There are reports of people acquiring conjunctivitis from harbor seals (
Phoca vitulina) during an epidemic among these animals, while other studies
have shown that the virus isolates from seals are capable of causing systemic
disease and death in non-human primates.
3
Tryland reports of many other diseases and epidemics in people that originated
from contact and exposure to sea mammals. Most notably are the large numbers
of indigenous peoples who have suffered from parasitic diseases such as Trichnellosis,
Toxoplasmosis and Giardiasis from eating contaminated, undercooked meat,
and drinking contaminated surface water.
3
Of the zoonotic disease reported in the literature these appear to be the
most thoroughly described and understood.
II. Research Question
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The documentation of humans infected with disease as a result of
contact with marine mammals is rare.
Many of the incidents in the literature were reported as first time disease
occurrences. Much is said about those
people in positions that put them in daily contact with both sick and apparently
healthy animals; however, this information does not allow for the extrapolation
of incidence of transmission, or the relative risk associated with transmission.
Additionally, much of the reports found are dated by, in some cases, 30 years.
Considering the new dynamics of human to marine mammal contact, from
trainer to tourist, more information is needed with regard to risk.
This project plans to document, via questionnaire and survey, the
cases of disease acquired from marine mammals by workers and volunteers at
facilities that house and hospitalize these animals. Facilities to be included
are aquariums, oceanariums, and wildlife rehabilitation centers.
Assessments will be made as to the number of occurrences and the
circumstances accompanying the human illnesses.
1. Buck CD,
and J. P. Schroeder. Public Health Significance
of Marine Mammal Diseases. Cleveland, OH.: CRC Press, 1990.
2. Sweeney
JCaR, S.H. Common Diseases of Small Cetaceans.
J of the American Vet Med Association 1975;167:533-540.
3. Tryland
M. Zoonoses of arctic marine mammals.
The Infectious Disease Review 2000;2:55-64.
4. Smith CWS.
Swimming with wild, friendly and playful dolphins is an experiance of a lifetime.,
2000.http://www.dolphindreamteam.com/trips/Dol%20trip/dolphintrip.html
5. Reiman
R, Basgall S. Dolphin Connection Programs, 1999. http://www.dolphinconnection.com/infoprint.txt
6. Taylor
A. Dolphin 'therapy' for a dying child: About.com, 1989. http://newage.about.com/gi/dynamic/offsite.htm?site=http%3A%2F%2Fwww.globalideasbank.org%2FGIB%2FBOV%2FBV-602.HTML
7. Streitfield
MM, and Chapman, C.G. Staphylococcus aureus infections of captive dolphins
(Tursiops truncatus) and oceanarium personnel.
American Journal of Veterinary Research 1976;37:303-305.
8. Flowers
DJ. Human infection due to Mycobacterium
marinum after a dolphin bite. Journal
of Clinical Pathology 1970;23:475-477.
9. Chastel
C MO, Balouet G, Laban P, Lucas A. The student, the cetacean and swine-fever.
A minor epidemic after dissection of a globicephale.
Nouv Presse Med 1975;Jun 14;4(24)::1803-5.
10. Hicks
BDaW, G.A. Sealpox in captive gray seals (
Halichoerus grypus) and their handlers.
Journal of Wildlife Diseases 1987;23:1-6.
11. Smith
AW, Vedros, N.A., Akers, T.G., and Gilmartin, W.G.,. Hazards of disease transfer
from marine mammals to mammals: Review and recent findings.
Journal of the American Veterinary Medical Association 1978;173:1131-1133.
12. Brew SD,
Perrett LL, Stack JA, et al. Human exposure to Brucella recovered from a
sea mammal [letter]. Veterinary Record
1999;144:483.
13. Foster.
G J, K.L., Reid, R.J. and Ross, H.M. Isolation of Brucella species from cetaceans,
seals and an otter. Veterinary Record
1996;138:583-586.
14. Thompson
PJ, Cousins DV, Gow BL, et al. Seals, seal trainers, and mycobacterial infection.
American Review of Respiratory Disease
1993;147:164-7.
15. Alexander
DJ, Brown IH. Recent zoonoses caused by influenza A viruses.
Revue Scientifique et Technique Office International des Epizooties 2000;19:197-225.