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UC Malaria Research and Control Group

Program Faculty and Collaborators

The UC Malaria Research and Control Group, part of the UC Statewide Mosquito Research Program, is a 21-member team comprised of scientists from four UC campuses and mosquito control experts from the Mosquito and Vector Control Association of California.

UC Davis: Gregory Lanzaro, Anthony Cornel, Bruce Hammock, Sharon Lawler, Walter Leal, Shirley Luckhart, Sergey Nuzhdin, William Reisen and Thomas Scott

UC Riverside: Peter Atkinson, Nancy Beckage, Ring Cardé, Brian Federici, Sarjeet Gill, Karine LeRoch, Alexander Raikhel and William Walton

UCLA: Charles Taylor

UC Irvine: Timothy Bradley, Anthony James and Guiyun Yan

UC Berkeley: Michael Levine

Mosquito and Vector Control Association of California: Christopher Voight


Peter Atkinson
Peter W. Atkinson
Professor, Department of Entomology
Institute for Integrative Genome Biology
University of California, Riverside
Expertise: Mosquito genetics and molecular biology
Research focus:

  • Genetic control strategies for mosquito vectors
  • Transposable elements and mosquito population genetics

Web site


Nancy Beckage
Nancy E. Beckage
Professor, Department of Entomology, Cell Biology and Neuroscience
University of California, Riverside
Research focus:

  • Physiological and molecular host-parasite relationships
  • Insect immunity, pathology, virology, endocrinology, and behavior
  • mosquito biology and biologically-based control strategies

Web site


Timothy Bradley
Timothy J. Bradley
Professor, Department of Ecology and Evolutionary Biology
University of California, Irvine
Expertise: Mosquito physiology, with special emphasis on salt and water balance, desiccation resistance, metabolic responses and energetics
Research focus:

  • Adaptations in larval mosquitoes to aquatic environments
  • Metabolic responses of adult insects to environmental stresses

Web site


Ring T. Cardé
Professor, Department of Entomology
University of California, Riverside
Expertise: Insect responses to semiochemicals, evolution of communication systems, and use of semiochemicals in pest management
Research focus:

  • Odor-guided mosquito behavior, attraction to odors and other cues from hosts and oviposition sites

Web site


Anthony J. Cornel
Associate professor, Department of Entomology
University of California, Davis
Expertise: Ecology, systematics, cytogenetics and control of mosquitoes
Research focus:

  • Population structure of Anopheles gambiae s.l. in sub Saharan Africa
  • Population structure of Culex pipiens s. l.--- in the USA and Africa
  • Mechanisms of insecticide resistance in Anopheles gambiae and Culex pipiens mosquito complexes

Web site
Research


Brian A. Federici
Professor, Department of Entomology
University of California, Riverside
Expertise: Insect pathology and microbial control with emphasis on viral and bacterial pathogens of medically important insects
Research focus:

  • Use of insecticidal bacteria as larvicides to control mosquito vectors of disease
  • Recombinant DNA techniques to construct mosquitocidal bacteria more than tenfold more effective than those currently used in commercial bacterial larvicides

Web site


Sarjeet S. Gill
Professor, Department of Cell Biology and Neuroscience
University of California, Riverside
Expertise: Insect biochemistry; insect and insecticide toxicology
Research focus:

  • Understanding transport pathways involved during blood feeding in mosquitoes
  • Identification of the molecular mechanisms involved in viral release in mosquitoes
  • Elucidation of the mechanisms of action of bacterial toxins used in mosquito control programs

Web site


Bruce D. Hammock
Professor, Department of Entomology
University of California, Davis
Expertise: Biochemistry and physiology of endocrine regulation in insects; disruption of chemical mediation by chemical means and biotechnology; comparative pesticide metabolism in insects and mammals; selective toxicity of pesticides
Research focus:

  • Metabolism of pyrethroid insecticides in insecticide resistant strains of mosquitoes
  • Natural toxins for possible mosquito control
  • Substrates for monitoring genes associated with insecticide resistance in mosquitoes
  • Purification of enzymes associated with insecticide resistance

Web site (home page)
Lab research:
Superfund Basic Research and Training Program
Laboratory of Pesticide and Biotechnology


Anthony A. James
Professor, Microbiology and Molecular Genetics, College of Medicine; and Molecular Biology and Biochemistry, School of Biological Sciences
University of California, Irvine
Expertise: Mosquito genetic and molecular genetic tools
Research focus:

  • Genetic and molecular genetic tools to interrupt parasite transmission by mosquitoes
  • Identification of vaccine and drug targets in malaria parasites

Web site


Gregory C. Lanzaro
Medical entomologist; director of the University of California Mosquito Research Program
School of Veterinary Medicine
Department of Pathology, Microbiology, and Immunology
University of California, Davis
Expertise: Genetics and population biology of mosquitoes that transmit malaria
Research focus:

  • Population and molecular genetics of insect vectors of human disease, with an emphasis on malaria in Africa
  • Molecular genetics and immunology of insect vector salivary proteins

VM:PMI faculty page
Lanzaro Vector Genetics Lab
UC Mosquito Research Program


Sharon P. Lawler
Associate professor, Department of Entomology
University of California, Davis
Expertise: Aquatic community ecology; non-target effects of mosquito control (both chemicals and introduced fish)
Research focus:

  • Effects of mosquito adulticides on aquatic invertebrates
  • Effects of irrigated rice management and flooding on mosquito populations

Web site


Walter S. Leal
Professor, Department of Entomology
University of California, Davis
Expertise: Molecular basis of olfaction
Research focus:

  • Molecular basis of mosquito olfaction, with particular emphasis on odorant binding, release, and inactivation
  • Chemical ecology- and sensory physiology-based approaches aimed at the discovery of novel attractants

Web site
Lab research


Karine G. Le Roch
Assistant professor, Department of Cell Biology and Neuroscience
University of California , Riverside
Expertise: Functional genomics of human malaria parasite ,Plasmodium falciparum
Research focus:

  • Functional genomics of human malaria parasite ,Plasmodium falciparum
  • Interactome of P. falciparum
  • Drug discovery against the malaria parasite

Web site


Michael Levine
Michael Levine
Professor of genetics and development
Department of Molecular and Cell Biology
University of California, Berkeley
Expertise: Gene networks that control animal development and disease.
Research focus:

  • Control of segmentation and gastrulation in the early Drosophila embryo
  • Immune response in Drosophila larvae
  • Differentiation of the notochord and heart in the sea squirt, Ciona intestinalis.

Web site
Lab research


Shirley Luckhart
Associate professor, Medical Microbiology and Immunology
School of Medicine, University of California, Davis
Expertise: Molecular cell biology and biochemistry of the interaction between malaria parasites and mosquito hosts
Research focus:

  • Characterization of mosquito gene products that inhibit malaria parasite development and molecular/biochemical analysis of parasite damage
  • Analysis of expression, signaling, and regulation of anti-parasite genes in Anopheles mosquitoes
  • Molecular and functional analyses of immune factors that are conserved between mosquitoes and their mammalian hosts.

Web site


Sergey V. Nuzhdin
Professor, Section of Evolution and Ecology
College of Biological Sciences
University of California, Davis
Expertise: Quantitative and population genetics, genomics
Research focus:

  • Evolutionary genetics of Drosophila, yeast, and mosquito

Web site


Alexander S. Raikhel
Professor, Department of Entomology
Director, Center for Disease-Vector Research
University of California, Riverside
Expertise: Molecular biology of insect disease vectors
Research focus:

  • Molecular mechanisms linking blood feeding with egg maturation
  • Mosquito immunity; reverse-genetics approach utilizing a transgenic technique

Web site


William K. Reisen
Research entomologist and adjunct professor
Director, Arbovirus Field Station, Center for Vector-Borne Disease Research, Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine
University of California, Davis
Expertise: Mosquito ecology
Research focus:

  • Population ecology of mosquitoes and their vertebrate hosts in relation to the epidemiology, surveillance and control of mosquito-borne pathogens
  • Ecology of mosquitoes and the pathogens they transmit

Web site


Thomas W. Scott
Professor, Department of Entomology
University of California, Davis
Expertise: Ecology, epidemiology, and prevention of mosquito-borne diseases
Research focus:

  • Mosquito ecology
  • Epidemiology of vector-borne disease
  • Vector control strategies for disease prevention

Web site
Mosquito Research Laboratory


Charles E. Taylor
Professor, Department of Entomology
University of California at Los Angeles (UCLA)
Expertise: Malaria and Anopheles gambiae
Research focus:

  • Population structure of Anopheles gambiae and closely related species in Africa
  • Population genomics of Anopheles gambiae

Web site


Christopher J. Voight
Executive director
Mosquito and Vector Control Association of California
Expertise: Surveillance, public education and mosquito control
Designing, setting up and manage large mosquito control programs.

Web site


William E. Walton
Professor, Department of Entomology
University of California, Riverside
Expertise: Biology, ecology and integrated pest management of mosquitoes
Research focus: Ecology and control of insect vectors of human disease, with an emphasis on the integrated management of mosquitoes inhabiting man-made and natural wetlands and irrigated agriculture

Web site


Guiyun Yan
Associate professor, Program in Public Health, College of Health Sciences
University of California, Irvine
Expertise: Mosquito population ecology and genetics, malaria epidemiology
Research focus:
Ecology of African highland malaria

  • Population ecology and genetics of African malaria vectors
  • Genetics of mosquito refractoriness to malaria parasites
  • Evolutionary genetics of host resistance to parasitism

Web site

 

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