Cecilia Giulivi
VM: Molecular Biosciences

CURRENT RESEARCH INTERESTS

• Biosynthesis of nitric oxide in mitochondria. Role of nitric oxide produced by mitochondria in cellular oxygen metabolism and vasodilation.


• Mitochondrial nitric oxide synthase: regulation of expression.


• Biosynthesis and metabolism of endogenous nitric oxide in mammalian cells. Role of nitric oxide, superoxide anion, and peroxynitrite anion
• in mediating pathophysiological processes.


• Mitochondrial nitrated proteins: role of nitration, metabolism of nitrated proteins, implications for pathophysiology.


• Oxygen and nitrogen free radical biochemistry and chemistry in in vitro and in vivo model systems. Mechanistic aspects of oxygen and nitrogen free radical damage.


• Proteomics of aging and oxidative damage of mitochondria.