Research in our laboratory has centered on optimization of gamete cryopreservation and development of new methods for preservation of male gametes. Alternative modes of sperm preservation beyond refrigeration and cryopreservation need to be developed for the efficient storage of genetically defined individuals or endangered species. Our study model is primarily the stallion but we also have active research in several other species. Our goals are to first to develop an understanding of fundamental mechanisms of cellular damage caused by low temperature storage, and then to use this knowledge to develop new methods for gamete preservation and subsequent fertility. We use a variety of techniques including lipid analysis, flow cytometry and confocal, fluorescence, and electron microscopy to evaluate the integrity of sperm cell organization and cell function. We have several strong collaborations and the lab is a member of the UC Davis Center for Biostabilization. For further information, please contact Dr. Meyers at smeyers@ucdavis.edu.