The role of neutrophils, lymphocytes and macrophages in oxidant induced epithelial injury and repair; airway inflammation and immunology in asthma and cystic fibrosis; postnatal ontogeny of pulmonary inflammation and immunology. Dr. Hyde's research is focused on airways epithelial and inflammatory/immune cell interaction. Interaction of these cells maintains homeostasis (ability to combat infectious disease, removal and/or repair of injured cells) in the lung. Pathways of leukocyte migration in the lung and the influence of these emigrational routes on endothelium, interstitial cells and matrix, and epithelium continue to be an interest. Lung growth, differentiation and aging, particularly under the perturbation of inhaled allergens and pollutants are more important research interests in the future. His laboratory will continue to use asthma, pulmonary fibrosis and emphysema as models for investigation.
Visit Dr. Hyde's website: http://faculty.vetmed.ucdavis.edu/faculty/dmhyde/