Disease Teams

Photo: Disease Teams

Dentistry, Oral & Maxillofacial
Cardiovascular
Inflammatory & Infectious
Ophthalmology
Orthopedic
Gasrointestinal and Tracheal
Wound Healing
Neurologic

Dentistry, Oral & Maxillofacial

The dentistry, oral & maxillofacial team is focused on establishing regenerative approaches in cats and dogsincluding:

  • Regeneration of mandibular bone in dogs after resective oncologic surgery or for non-union fractures.
  • Stem cell therapy for cats with chronic gingivostomatitis, a severe and debilitating immune-mediated disorder.
  • The incorporation of additive manufacturing (3D printing) and regenerative approaches to maxillofacial trauma repair.

Members: Boaz Arzi, Frank Verstraete, Kyriacos Athanasiou

Cardiovascular

The cardiovascular team is focused on novel strategies to repair heart tissue, valves and small vessels. Strategies include stem cell therapy and tissue engineering.

Members: David Simpson, Kent Leach, Eduardo Silva

Inflammatory & Infectious

The Inflammatory and Infectious disease team is focused on immunomodulation by MSCs for the treatment of acute and chronic inflammatory lesions as well as the systemic inflammatory sequela of some chronic infectious diseases such as FIV, SIV, and HIV.

Members: Dori Borjesson, Amir Kol, Satya Dandekar

Ophthalmology

The ophthalmology team is focused on the treatment of keratoconjunctivitis sicca, corneal wounds and recurrent uveitis.

Members: Chris Murphy, Paul Russell, Steve Hollingsworth

Orthopedic

The orthopedic team is focused on the treatment of acute and chronic orthopedic injuries. Projects include:

  • Treatment of chronic active and acute laminitis.
  • Treatment of acute suspensory ligament desmitis (branches).
  • Development of clinical trials for the treatment of equine foot lesions including distal deep flexor tendon and collateral body ligaments.

Members: Larry Galuppo, Claudia Sonder, Clare Yellowley

Gastrointestinal & Tracheal / Esophageal

The gastrointestinal team is focused on the treatment inflammatory bowel disease.

Members: Dori Borjession, Stanley Marks, Amir Kol

Wound Healing

The wound healing team is focused on the treatment of chronic non-healing wounds in horses.
Active research centers around the development of an experimentally induced foreleg wound model to mimic non-healing wounds (proud flesh) in horses and keloid formation in humans and determining if cellular therapy using “pre-conditioned” stem cells facilitates wound repair.

Members: Dori Borjesson, Claudia Sonder, Larry Galuppo

Neurologic

The neurologic team is focused on spinal cord regeneration and repair and treatment of inflammatory brain disease using stem cells

Members: Mathieu Spriet, Dori Borjesson, Jan Nolta, Maya Sieber-Blum, Beverley Sturges, Aijun Wang