Diagnostic Flowchart for EPM

EPM Diagnostic Flow Chart

EPM Diagnostic Flow Chart

Diagnostic flow chart

  1. History, physical evaluation, neurological examination, minimal data base (CBC/biochemical panel)
    1. Not compatible with EPM
      1. Other diagnotic tests based on neuro-anatomic localizations
    2. Compatible with EPM
      1. SarcoFluor™ and NeoFluor™ serologic testing
  2. Results of SarcoFluor™ and NeoFluor™ serologic testing
    1. Serum titer: S.neurona <40, N.hughesi <160
      1. Not EPM
    2. Serum titer: S.neurona >80, N.hughesi >320
      1. Laboratory support of EPM
    3. Serum titer: S.neurona 40-80, N.hughesi 160-320
      1. Collect CSF for cytology and SarcoFluor™ and NeoFluor™ testing to rule out EPM
  3. Results of SarcoFluor™ and NeoFluor™ CSF testing
    1. CSF titer for S.neurona and/or N.hughesi < 5
      1. Not EPM
    2. CSF titer for S.neurona and/or N.hughesi ≥ 5
      1. Laboratory support of EPM
  4. Contact UC Davis Veterinary Medical Teaching Hospital, Large Animal Clinic for further assistance

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Diagnostic Flow Chart (jpg)

Diagnostic Flow Chart (pdf)