Case Studies In Small Animal

Cardiovascular Medicine

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Case 22


Chimere was treated with ticarcillin administered intravenously for one week following the definitive diagnosis of infective (bacterial) endocarditis. She was then placed on Clavamox as an oral agent for the following three weeks. During that time, Chimere gradually improved. She became stronger, had no recurrence of fever, and ate and gained weight. One month after the first echocardiogram (approximately five weeks after being started on antibiotics) her owner brought her back for another echocardiogram.

On physical exam, she looked reasonably normal for a 13-year-old dog. She walked stiffly but was bright and alert. The first surprising thing was that she had no heart murmur. The follow-up echocardiograms are below.

The echocardiograms were a total surprise. This is by far the most amazing response I've ever seen in a dog with bacterial endocarditis. Although Chimere had had no evidence of thromboembolic disease since starting antibiotics, the lesions were completely gone and so apparently had completely regressed. There were no lesions on either valve leaflet and no evidence of mitral regurgitation.

Since then the owner has decided to keep Chimere on Clavamox and she has continued to do well. Hopefully she will continue to have a long and happy life.

Mark D. Kittleson, D.V.M., Ph.D. All rights reserved.