PhD candidate Mandy Murray, DVM, MPVM, uses a microscope to asses histology of bone in the study of Silicate Associated Osteoporosis.
Silicosis Associated Osteoporosis
Silicate Associated Osteoporosis
We are investigating a recently identified disease in horses in which the bones become weak and osteoporotic. Research is focused on 1) determining what happens to the bones on microscopic level and 2) identifying the underlying mechanism of the disease. The ultimate goal of the research is to find optimal management of the affected horses and prevention strategies. Because many of the horses with the bone disease also have a lung disease called pulmonary silicosis, we are pursuing understanding of the link between the lung disease and the bone disease.
Dr. Mandy (Murray) Arens has greatly advanced our understanding of SAO through her remarkable work and has completed her PhD in 2011. Dr. Regina Zavodovskaya, with interest is bone pathology, presently continues the investigation of SAO.
Anderson J, Galuppo, L., Barr, B., Puchalski, S., MacDonald, M., Magdesian,G, Stover, SM.: Scintigraphic findings and clinical characterization of a bone fragility disorder in horses: 16 cases (1980-2006). Journal of American Veterinary Medical Association 232: 1694-1699, 2008
Durham M, Armstrong, CM: Fractures and Bone Deformities in 18 horses with Silicosis. Proceedings of the 52nd Annual Convention of the American Association of Equine Practitioners, San Antonio, Texas, USA, 2-6 December, 2006. 311-317
Regina Zavodovskaya, MS, DVM, Dipl ACVP
Susan M. Stover, DVM, PhD, Dipl ACVS