Archived News

Latest Clinical Trials at UC Davis


April 29, 2016

Dr. Boaz Arzi and Megan Badgley, RVT, examine Morris, a patient in the feline chronic gingivostomatitis trial.

Dr. Boaz Arzi and Megan Badgley, RVT, examine Morris, a patient in the feline chronic gingivostomatitis trial.

Since its inception in 2013, the UC Davis Veterinary Center for Clinical Trials (VCCT) has completed dozens of studies, and more than 100 new trials are currently being conducted. VCCT works closely with the veterinary hospital and other campus institutions including the School of Medicine, the Clinical and Translational Science Center, the Center for Companion Animal Health, the Center for Equine Health, and the Veterinary Institute for Regenerative Cures. Clinical investigators have active trials aimed at advancing medical care for veterinary patients in a variety of disciplines, including oncology, neurology/neurosurgery, ophthalmology, dermatology and cardiology.

While the hospital provides the highest standard of care through conventional methods, clinical trials allow UC Davis veterinarians to evaluate new scientific breakthroughs that have the potential to improve the diagnosis and treatment of diseases. Veterinary clinical trials through the VCCT assess promising new treatments, drugs or procedures, but only after preliminary studies have established that the new methods are safe and have the potential to work better than existing protocols.

For more information about the VCCT and the current clinical trials at UC Davis, visit www.vetmed.ucdavis.edu/clinicaltrials or email vetclintrials@ucdavis.edu.

A few current trials at UC Davis include:

Bladder Stones (Struvite) in Dogs
Dr. Jodi Westropp is recruiting for struvite in dogs to provide another option to bladder stone dissolution. The purpose of this trial is to evaluate the efficacy of a therapeutic diet to help determine another dietary method for non-invasive dissolution.

Chronic Gingivostomatitis in Cats
Dr. Boaz Arzi is having success with a new stem cell approach to treating feline chronic gingivostomatitis (FCGS). None of the treatments for FCGS that are currently available are ideal, predictable and without possible complications. The purpose of this study is to treat cats for which all current treatment modalities have failed and have a poor quality of life.

Osteoarthritis in Dogs
Dr. Duane Robinson is recruiting for osteoarthritis in dogs. The primary purpose of this study is to test two investigational medications to determine if either one, or both, work to potentially decrease signs of pain of osteoarthritis in dogs.

Bilateral Corneal Stromal Loss in Friesian Horses
Dr. Mary Lassaline is recruiting for a new clinical trial for Friesian horses diagnosed with bilateral corneal stromal loss (BCSL). The trial focuses on determining the incidence of BCSL in the breed and the mode of inheritance if a single gene is involved, and identifying candidate genes for further investigation. Owners are encouraged to enroll Friesian horses with and without the diagnosis of BCSL.

Fungal Infections (Aspergillus spp) in German Shepherds, Rhodesian Ridgebacks, and Hungarian Vizslas
Dr. Jonathan Dear is recruiting patients for his study on aspergillosis, a rare infection in animals with competent immune systems; however, certain dog breeds (namely the German shepherd, Rhodesian ridgeback and Hungarian vizsla) are reported to have a higher risk of this uncommon disease. A genome-wide association analysis will be used to evaluate the differences in the genetic material of affected dogs.

Leopard Complex Spotting in Appaloosa Horses
Dr. Rebecca Bellone is recruiting for leopard complex spotting in Appaloosa horses, which is characterized by the progressive loss of pigment and has been associated with uveitis and night blindness in several breeds of horses. Two genes have been previously implicated in the loss of pigment in Appaloosas. This trial will investigate the morphology of the pigment producing cells (melanocytes) and determine if any ultrastructural differences exist among varying Appaloosa genotypes.

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About the Veterinary Medical Teaching Hospital
The William R. Pritchard Veterinary Medical Teaching Hospital at the University of California, Davis—a unit of the #1 world ranked School of Veterinary Medicine—provides state-of-the-art clinical care while serving as the primary clinical teaching experience for DVM students and post graduate veterinarian residents. The VMTH treats more than 51,000 animals a year, ranging from cats and dogs to horses, cows and exotic species. To learn more about the VMTH, please go to www.vetmed.ucdavis.edu/vmth. Timely news updates can be received on its Facebook (www.facebook.com/ucdavisvetmed) and Twitter (www.twitter.com/ucdavisvetmed) pages.

Media Contact:
Rob Warren
VMTH Communications & Marketing Officer
rjwarren@ucdavis.edu
530-752-2363