Event Date
MIC (Microbiology Course) 291: Selected Topics in Microbiology
Work-in-Progress Seminars
PhD Exit Seminar
Speaker: Suyakarn "Sonia" Archasappawat, DVM, PhD Candidate, Dr. Chang-il Hwang’s lab, Department of Microbiology and Molecular Genetics, University of California, Davis
Dr. Archasappawat presents: “Reading, Rewiring, Rerouting: Therapeutic Vulnerability and Resistance to BET Inhibitors in Pancreatic Cancer”
About the speaker: Suyakarn "Sonia" Archasappawat is a PhD candidate in Integrative Pathobiology. In the lab of Dr. Chang-il Hwang, she studies how genetic and epigenetic programs shape treatment response in pancreatic ductal adenocarcinoma (PDAC), one of the deadliest cancers with limited durable treatment options.
About the seminar: In this seminar, she will discuss recent work on bromodomain and extra-terminal domain (BET) protein inhibitors in PDAC, focusing on two key questions: why BRCA2-deficient pancreatic cancer is particularly sensitive to BET inhibition, and how adaptive resistance mechanisms may emerge and be overcome to improve long-term response.
Host: Chang-il Hwang