Dallas M Hyde
Professor Emeritus
Professor Emeritus
Anatomy, Physiology & Cell Biology
Anatomy, Physiology & Cell Biology
Research Profile
Education
1971, BA, University of California at Irvine, Irvine, CA
1972, MS, Whittier College, Whittier, CA
1976, PhD, University of California at Davis, Davis, CA
Active Research Grants
Co-Investigator, Training in Comparative Lung Biology and Medicine, Reen Wu (Principal Investigator), NIH/NHLBI
Co-Investigator, Postdoctoral Training in Environmental Pathology, Dennis Wilson (Principal Investigator), NIH/NIEHS
Co-Investigator, Advanced Training Environmental Health Sciences, Robert Rice (Principal Investigator), NIH/NIEHS
Co-Investigator, Comparative Medical Science Training Program, Stephen Barthold (Principal Investigator), NIH/NCRR
Principal Investigator, Pulmonary Effects of Environmental Oxidant Pollutants, (Principal Investigator), NIH/NIEHS
Principal Investigator, AARA Supplement - Translational - California National Primate Research Center, (Principal Investigator), NIH/NCRR
Co-Investigator, Roles of IL-17-induced gene expression in airway epithelial host defense, Reen Wu (Principal Investigator), National Institutes of Health
Honors and Awards
1974-1976 Fellow, Walter Foster Foundation, SVM, Department of Anatomy, University of California, Davis
1978 Teaching Award of Appreciation for Musculoskeletal System for Veterinary Class of 1981, University of Florida
1979 Teaching of the Yeard Award given by the Class of 1982, University of Florida
1985-1986 National Research Service Award Senior Fellowship, NIH, National Jewish Hospital Denver, Colorado
1999 Pfizer Award for Research Excellence, School of Veterinary Medicine, University of California, Davis
2009 Outstanding Veterinary Anatomist Award, American Association of Veterinary Anatomists
2011 Fellow of the American Association of Anatomists
2010 Distinguished Professor
Most Recent Five Book Chapters
2008 Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM: Primate Models of Allergic Asthma, Kay AB, Kaplan AP, Bousquet J, Holt PG, (ed), Allergy and Allergic Diseases, Second Edition, London. 1185-1201.
2008 Hyde DM, Miller LA, Schelegle ES, Fanucchi MV, Van Winkle LS, Tyler NK, Avdalovic MV, Evans MJ, Kajekar R, Buckpitt AR, Pinkerton KE, Joad JP, Gershwin LJ, Wu R, Plopper CG: Chronic Airway Disease in Nonhuman Primates, N. F. Voelkel and W. MacNee, (ed), Chronic Obstructive Lung Diseases, Hamilton. 235-268.
2005 Albertine KH, Williams MC, Hyde DM: Anatomy and Development of the Respiratory Tract, Mason RJ, Broaddus VC, Murray JF, Nadel JA, (ed), Murray and Nadel's Textbook of Respiratory Medicine, Philadelphia. 3-41.
2001 Plopper CG, Paige R, Schelegle ES, Buckpitt A, Wong V, Tarkington B, Putney L, Hyde DM: Time-response profiles: Implications for injury, repair, and adaptation to ozone, U. Heinrich and U. Mohr, (ed), Relationships Between Acute and Chronic Effects of Air Pollution, Washington, DC. 23-37.
2001 Pinkerton KE, Murphy KM, Hyde DM: Morphology and morphometry of the lung, U. Mohr, W.W. Carlton, D.L. Dungworth, S.A. Benjamin, C.C. Capen and F.F. Hahn, (ed), Pathobiology of the Aging Dog, Ames, IA. 43-56.
Research Focus
My research is focused on airways epithelial and inflammatory/immune cell interaction. Interaction of these cells maintains homeostasis (ability to combat infectious disease, removal and/or repair of injured cells) in the lung. My laboratory is interested in asthma, pulmonary fibrosis and chronic obstructive lung disease as models for investigation. My current investigations are in the asthma model and its exacerbation by the oxidant air pollutant ozone. I am investigating how perturbation of the airway and parenchymal epithelium influences remodeling of the underlying interstitium which in turn influences the epithelium in an interactive epithelial-mesenchymal trophic unit (EMTU). My goal is to define the critical cytokines produced by the epithelium required to maintain homeostasis in the EMTU and prevent airways and parenchymal remodeling that lead to altered lung function.
Specialty Focus
Stereology, Inflammation, Airway structure and function, Lung parenchyma structure and function