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Jennifer Michelle Cassano

Jennifer Michelle Cassano

Assistant Professor

Medicine & Epidemiology


Licenses
California Veterinary License
USDA Category II Accredited Veterinarian
Drug Enforcement Agency Licensure
Education
2009, BS, Cornell University, College of Agriculture and Life Sciences, Ithaca, New York
2013, DVM, Cornell University, College of Veterinary Medicine, Ithaca, New York
2016, PhD, Cornell University, College of Veterinary Medicine, Ithaca, New York
Active Research Grants
Co-Principal Investigator, Stem cell therapy for persistent bacterial infection in dogs following total ear canal ablation, Krystle Reagan (Principal Investigator), Center for Companion Animal Health
Co-Investigator, Activated Mesenchymal Stem Cell Therapy for Resistant Bacterial Bone Infections, Barbro Filliquist (Principal Investigator), Center for Companion Animal Health
Co-Principal Investigator, Feline allo MSC enhancement with adenosine-loaded nanoparticles, Natalia Vapniarsky-Arzi (Principal Investigator), WINN Foundation
Co-Investigator, Feline allo MSC enhancement with adenosine-loaded nanoparticles, Natalia Vapniarsky-Arzi (Principal Investigator), Center for Companion Animal Health
Research Focus
Immunology and regenerative medicine
Specialty Focus
My research interests and expertise are in immunology and regenerative medicine, and my research seeks to better understand how modulation of the immune response can be harnessed in therapeutic treatments. My clinical focus is equine preventative medicine, management of equine metabolic diseases, and ophthalmology. As an educator I seek to promote mental health and wellness in the veterinary profession.
Ten Recent Publications

2022
Bernardino PN, Smith WA, Galuppo LD, Mur PE, Cassano JM^
Therapeutics prior to mesenchymal stromal cell therapy improves outcome in equine orthopedic injuries.

2018
Cassano JM, Fortier LA, Hicks RB, Harman RM, Van de Walle GR
Equine mesenchymal stromal cells from different tissue sources display comparable immune-related gene expression profiles in response to interferon gamma (IFN)-?.

2018
Cassano JM, Kennedy JG, Ross KA, Fraser EJ, Goodale MB, Fortier LA
Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration.

2018
Cassano JM, Schnabel LV, Goodale MB, Fortier LA
Inflammatory licensed equine MSCs are chondroprotective and exhibit enhanced immunomodulation in an inflammatory environment.

2018
Cassano JM, Schnabel LV, Goodale MB, Fortier LA
The immunomodulatory function of equine MSCs is enhanced by priming through an inflammatory microenvironment or TLR3 ligand.

2017
Hill JA, Cassano JM, Goodale MB, Fortier LA
Antigenicity of mesenchymal stem cells in an inflamed joint environment.

2017
Lang HM, Schnabel LV, Cassano JM, Fortier LA
Effect of needle diameter on the viability of equine bone marrow derived mesenchymal stem cells.

2016
Staiger EA, Tseng CT, Miller D, Cassano JM, Nasir L, Garrick D, Brooks SA, Antczak DF
Host genetic influence on papillomavirus-induced tumors in the horse.

2015
Cassano JM, Schnabel L V, Betancourt AM, Antczak DF, Fortier LA
Mesenchymal Stem Cell Therapy: Clinical Progress and Opportunities for Advancement

2015
Pezzanite LM, Fortier LA, Antczak DF, Cassano JM, Brosnahan MM, Miller D, Schnabel LV
Equine allogeneic bone marrow-derived mesenchymal stromal cells elicit antibody responses in vivo.