Rachel Reader

Rachel Reader

Health Science Clinical Professor

Pathology, Microbiology & Immunology

Office
Primate Medicine Trailer / Pathology, Davis, CA 95616

Licenses
Diplomate of the American College of Veterinary Pathology
Education
1986, BVSc hons, University of Liverpool, , Liverpool UK
2002, PhD, University of California, Davis
Research Focus
Diagnostic and experimental pathology to support colony health and biomedical research.
Specialty Focus
Comparative pathology of laboratory animals
Ten Recent Publications

2022
Langel SN, Garrido C, Phan C, Travieso T, Kirshner H, DeMarco T, Ma ZM, Reader JR, Olstad KJ, Sammak RL, Shaan Lakshmanappa Y, Roh JW, Watanabe J, Usachenko J, Immareddy R, Pollard R, Iyer SS, Permar S, Miller LA, Van Rompay KKA, Blasi M
Dam-Infant Rhesus Macaque Pairs to Dissect Age-Dependent Responses to SARS-CoV-2 Infection

2022
Van Rompay KKA, Olstad KJ, Sammak RL, Dutra J, Watanabe JK, Usachenko JL, Immareddy R, Roh JW, Verma A, Shaan Lakshmanappa Y, Schmidt BA, Di Germanio C, Rizvi N, Liu H, Ma ZM, Stone M, Simmons G, Dumont LJ, Allen AM, Lockwood S, Pollard RE, Ramiro de Assis R, Yee JL, Nham PB, Ardeshir A, Deere JD, Jain A, Felgner PL, Coffey LL, Iyer SS, Hartigan-O'Connor DJ, Busch MP, Reader JR
Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation

2021
Deere JD, Carroll TD, Dutra J, Fritts L, Sammak RL, Yee JL, Olstad KJ, Reader JR, Kistler A, Kamm J, Di Germanio C, Shaan Lakshmanappa Y, Elizaldi SR, Roh JW, Simmons G, Watanabe J, Pollard RE, Usachenko J, Immareddy R, Schmidt BA, O'Connor SL, DeRisi J, Busch MP, Iyer SS, Van Rompay KKA, Hartigan-O'Connor DJ, Miller CJ
SARS-CoV-2 Infection of Rhesus Macaques Treated Early with Human COVID-19 Convalescent Plasma.

2021
Jiang S, Mukherjee N, Bennett RS, Chen H, Logue J, Dighero-Kemp B, Kurtz JR, Adams R, Phillips D, Schürch CM, Goltsev Y, Hickey JW, McCaffrey EF, Delmastro A, Chu P, Reader JR, Keesler RI, Galván JA, Zlobec I, Van Rompay KKA, Liu DX, Hensley LE, Nolan GP, McIlwain DR
Rhesus Macaque CODEX Multiplexed Immunohistochemistry Panel for Studying Immune Responses During Ebola Infection.

2021
Liu H, Plancarte M, Ball EE, Weiss CM, Gonzales-Viera O, Holcomb K, Ma ZM, Allen AM, Reader JR, Duignan PJ, Halaska B, Khan Z, Kriti D, Dutta J, van Bakel H, Jackson K, Pesavento PA, Boyce WM, Coffey LL
Respiratory Tract Explant Infection Dynamics of Influenza A Virus in California Sea Lions, Northern Elephant Seals, and Rhesus Macaques.

2021
Van Rompay KKA, Olstad KJ, Sammak RL, Dutra J, Watanabe JK, Usachenko JL, Immareddy R, Verma A, Shaan Lakshmanappa Y, Schmidt BA, Roh JW, Elizaldi SR, Allen AM, Muecksch F, Lorenzi JCC, Lockwood S, Pollard RE, Yee JL, Nham PB, Ardeshir A, Deere JD, Patterson J, Dang Q, Hatziioannou T, Bieniasz PD, Iyer SS, Hartigan-O'Connor DJ, Nussenzweig MC, Reader JR
Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques.

2021
Verma A, Hawes CE, Lakshmanappa YS, Roh JW, Schmidt BA, Dutra J, Louie W, Liu H, Ma ZM, Watanabe JK, Usachenko JL, Immareddy R, Sammak RL, Pollard R, Reader JR, Olstad KJ, Coffey LL, Kozlowski PA, Hartigan-O'Connor DJ, Nussenzweig M, Van Rompay KKA, Morrison JH, Iyer SS
Monoclonal antibodies protect aged rhesus macaques from SARS-CoV-2-induced immune activation and neuroinflammation.

2020
Oldt RF, Bussey KJ, Settles ML, Fass JN, Roberts JA, Reader JR, Komandoor S, Abrich VA, Kanthaswamy S
MYBPC3 Haplotype Linked to Hypertrophic Cardiomyopathy in Rhesus Macaques (Macaca mulatta).

2020
Elizaldi S, Lakshmanappa YS, Roh J, Schmidt B, Carroll T, Weaver K, Smith J, Deere J, Dutra J, Stone M, Franz S, Sammak R, Olstad K, Reader JR, Ma ZM, Nguyen N, Watanabe J, Usachenko J, Immareddy R, Yee J, Weiskopf D, Sette A, Hartigan-O'Connor D, McSorley S, Morrison J, Tran N, Simmons G, Busch M, Kozlowsk P, van Rompay K, Miller C, Iyer S
SARS-CoV-2 infection induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques