Sandipan Datta

Sandipan Datta

Assistant Project Scientist

Molecular Biosciences


Education
2012, PhD, University of Mississippi, Oxford, Mississippi
2006, MS, University of Mississippi, Oxford, Mississippi
2003, BS, University of Mississippi, Oxford, Mississippi
Active Research Grants
Co-Investigator, Determination of human tissue QACs concentration and their partitioning into mitochondria, Gino Cortopassi (Principal Investigator), NIEHS Core Center UC Davis
Honors and Awards
2011 Outstanding service to the Department of Pharmacognosy, University of Mississippi
2010 Who's who among the American college students
2006 Gold Medalist in Master of Pharmaceutical Sciences
Research Focus
Mitochondrial disease, Cancer metabolism, drug discovery, natural products
Specialty Focus
mitochondrial physiology & pharmacology, natural products
Ten Recent Publications

2018
Teixeira J, Amorim R, Santos K, Soares P, Datta S, Cortopassi GA, Serafim TL, Sardão VA, Garrido J, Borges F, Oliveira PJ
Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative.

2017
Datta S, Baudouin C, Brignole-Baudouin F, Denoyer A, Cortopassi GA
The Eye Drop Preservative Benzalkonium Chloride Potently Induces Mitochondrial Dysfunction and Preferentially Affects LHON Mutant Cells.

2017
Datta S, He G, Tomilov A, Sahdeo S, Denison MS, Cortopassi G
In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride.

2017
Kathrani A, Larsen JA, Cortopassi G, Datta S, Fascetti AJ
A descriptive pilot study of cytokine production following stimulation of ex-vivo whole blood with commercial therapeutic feline hydrolyzed diets in individual healthy immunotolerant cats.

2017
Yu AK, Datta S, McMackin MZ, Cortopassi GA
Rescue of cell death and inflammation of a mouse model of complex 1-mediated vision loss by repurposed drug molecules.

2016
Darr CR, Cortopassi GA, Datta S, Varner DD, Meyers SA
Mitochondrial oxygen consumption is a unique indicator of stallion spermatozoal health and varies with cryopreservation media.

2016
Darr CR, Varner DD, Teague S, Cortopassi GA, Datta S, Meyers SA
Lactate and Pyruvate Are Major Sources of Energy for Stallion Sperm with Dose Effects on Mitochondrial Function, Motility, and ROS Production.

2016
Datta S, Sahdeo S, Gray JA, Morriseau C, Hammock BD, Cortopassi G
A high-throughput screen for mitochondrial function reveals known and novel mitochondrial toxicants in a library of environmental agents.

2016
Datta S, Tomilov A, Cortopassi G
Identification of small molecules that improve ATP synthesis defects conferred by Leber's hereditary optic neuropathy mutations.

2014
Datta S, Mahdi F, Ali Z, Jekabsons MB, Khan IA, Nagle DG, Zhou YD
Toxins in botanical dietary supplements: blue cohosh components disrupt cellular respiration and mitochondrial membrane potential.