Terza Brostoff

Terza Brostoff

Assistant Agronomist and Assistant Professor

Pathology, Microbiology & Immunology


Licenses
Diplomate, American College of Veterinary Microbiology
California Veterinary License #22206
Education
2009, B.A., University of California, Berkeley, Berkeley, CA, USA
2017, D.V.M., University of California, Davis, Davis, CA, USA
2015, Ph.D., University of California, Davis, Davis, CA, USA
2023, Postdoctoral Fellow, University of California, San Diego,
Active Research Grants
Principal Investigator, Foundational steps towards a novel feline infectious peritonitis mRNA vaccine: in vitro kinetics, expression, and lipid nanoparticle packaging of feline coronavirus nucleocapsid mRNA, (Principal Investigator), Morris Animal Foundation
Principal Investigator, Development of a novel diagnostic test for canine osteosarcoma using Raman spectroscopy, (Principal Investigator), American Kennel Club Canine Health Foundation
Principal Investigator, Developing a blood test to diagnose and understand mechanisms of canine osteosarcoma, (Principal Investigator), Center for Companion Animal Health
Co-Investigator, Establishment of flow cytometry protocol to investigate prognostic markers in canine cancer, Hannah Savage (Principal Investigator), Center for Companion Animal Health
Honors and Awards
2010 Students Training in Advanced Research NIH T-35 Scholarship
2010-2017 Veterinary Scientists Training Program
2011 Students Training in Advanced Research NIH T-35 Scholarship
2011-2012 Year-Long Exposure to Advanced Research NIH T-32 Scholarship
2012-2013 Clinical and Translational Science Center NIH T-32 Scholarship
2014 Malcolm Stacey Fellowship, UC Davis
2014 Students Training in Advanced Research NIH T-35 Scholarship
2014 UC Davis Career Exploration Through Internships program
2014 UC Davis Graduate Group in Integrative Pathobiology Colloquium Student Poster Award
2014 American College of Veterinary Pathologists Student Poster Award, Natural Disease category
2014-2015 Valentine Fellowship
2015 Students Training in Advanced Research NIH T-35 Scholarship
2016 Patrick McInturff III Memorial Endowed Scholarship
2016 Dr. Jacob Traum Endowed Scholarship
2016-2017 P.E.O. Scholar Award fellowship for women in science
2017 Quinton R. Rogers - Nestle Purina Scholarship for Achievement in Feline Medicine or Nutrition
2017 R.S. Robertson Scholarship
2020-2023 UCSD Research Training Program for Veterinarians, NIH T-32 Scholarship
Research Focus
Understanding the immune response to vaccination and natural infection in order to develop improved vaccines and diagnostic testing.
Specialty Focus
Development of Raman spectroscopy to diagnose infectious and noninfectious diseases of veterinary species
Ten Recent Publications

2024
Brostoff T, Savage HP, Jackson KA, Dutra JC, Fontaine JH, Hartigan-O'Connor DJ, Carney RP, Pesavento PA
Feline Infectious Peritonitis mRNA Vaccine Elicits Both Humoral and Cellular Immune Responses in Mice

2024
Liu H, Brostoff T, Ramirez A, Wong T, Rowland DJ, Heffner M, Flores A, Willis B, Evans JJ, Lanoue L, Lloyd KCK, Coffey LL
Establishment and characterization of an hACE2/hTMPRSS2 knock-in mouse model to study SARS-CoV-2

2024
Murphy BG, Castillo D, Neely NE, Kol A, Brostoff T, Grant CK, Reagan KL
Serologic, Virologic and Pathologic Features of Cats with Naturally Occurring Feline Infectious Peritonitis Enrolled in Antiviral Clinical Trials

2024
Reagan KL, Brostoff T, Pires J, Rose A, Castillo D, Murphy BG
Open label clinical trial of orally administered molnupiravir as a first-line treatment for naturally occurring effusive feline infectious peritonitis

2023
Sariano PA, Mizenko RR, Shirure VS, Brandt AK, Nguyen BB, Nesiri C, Shergill BS, Brostoff T, Rocke DM, Borowsky AD, Carney RP, George SC
Convection and extracellular matrix binding control interstitial transport of extracellular vesicles

2022
Mizenko RR, Brostoff T, Jackson K, Pesavento PA, Carney RP
Extracellular Vesicles (EVs) Are Copurified with Feline Calicivirus, yet EV-Enriched Fractions Remain Infectious

2021
Mizenko RR, Brostoff T, Rojalin T, Koster HJ, Swindell HS, Leiserowitz GS, Wang A, Carney RP
Tetraspanins are unevenly distributed across single extracellular vesicles and bias sensitivity to multiplexed cancer biomarkers

2016
Brostoff T, Pesavento PA, Barker CM, Kenney JL, Dietrich EA, Duggal NK, Bosco-Lauth AM, Brault AC
MicroRNA reduction of neuronal West Nile virus replication attenuates and affords a protective immune response in mice

2016
Pesavento PA, Brostoff T, Church ME, Dela Cruz FN, Woolard KD
Polyomavirus and Naturally Occuring Neuroglial Tumors in Raccoons (Procyon Lotor)

2014
Brostoff T, Dela Cruz FN, Church ME, Woolard KD, Pesavento PA
The raccoon polyomavirus genome and tumor antigen transcription are stable and abundant in neuroglial tumors