Amelie Es Segarra

Amelie Es Segarra

Assistant Adjunct Professor

Anatomy, Physiology & Cell Biology


Education
2014, Ph.D. in Marine Health Biology, Southern Brittany University, France,
2010, Master’s in Biotechnology, Sup'Biotech, France,
2008, Bachelor’s in Biotechnology, Sup'Biotech, France
Active Research Grants
Co-Principal Investigator, Development of a Response Spectrum Framework to Assess the Effects of Pesticide Residues in Central Valley Salmon, Connon R (Principal Investigator), CA Department of Fish and Wildlife
Co-Principal Investigator, Whole Animal New Approach Methodologies for Predicting Developmental Effects of Air Pollutant Mixtures, Helen Poynton (Principal Investigator), US EPA STAR
Principal Investigator, When the rubber meets the river: an assessment of 6PPD-quinone toxicity on Delta species of conservation concern, (Principal Investigator), CA Department of Fish and Wildlife
Principal Investigator, Post-drought wildfire retardant effects on Chinook Salmon and Rainbow Trout alevin, comparing across Phos-Chek formulations to better understand potential environmental impacts, (Principal Investigator), Delta Stewardship Council
Co-Principal Investigator, Reconnecting Winter run to their ancestral waters: monitoring reintroduction success on the McCloud , Carson J. (Principal Investigator), CA Department of Fish and Wildlife
Co-Principal Investigator, Applying a response spectrum model to assess spatial and temporal differences in effects of pesticide mixtures on juvenile Chinook Salmon in the Delta, Connon R. (Principal Investigator), State water contractors
Principal Investigator,  Can the Sacramento Deep-Water Shipping Channel be a source of nutrients to Delta Smelt and their prey or will contaminants spoil the party? A contaminant prospective, (Principal Investigator), CA Department of Fish and Wildlife
Research Focus
My research focuses on understanding how aquatic organisms contend with anthropogenic and environmental stressors, including contaminants, pathogens and their interactions with climate change. I use aquatic species as research models, such as zebrafish (Danio rerio) for environmental toxicology purposes, as well as salmon (Oncorhynchus tshawytscha) and non-model species of conservation concern for ecological toxicology. My research is integrative, using multidisciplinary approaches including molecular biology, immunology, behavior, and physiology, combining both field- and laboratory-based studies.
Specialty Focus
Environmental Toxicology and Aquatic Animal Diseases
Ten Recent Publications

2025
Cominassi L, Segarra A^, Chandler A, Habibullah-Al-Mamun M, Knaub K, Huff Hartz KE, Mauduit F, Fangue N, Whitledge GW, Lydy MJ, Connon RE
Sub-lethal exposures to bifenthrin impact stress responses and behavior of juvenile Chinook Salmon.

2024
Huff Hartz KE, Knaub KJ, Al-Mamun MH, Connon RE, Whitledge GW, Segarra A, Lydy MJ
Using an internal body residue approach to assess acute pesticide toxicity in juvenile Chinook salmon (Oncorhynchus tshawytscha)

2024
Hutton SJ, Siddiqui S, Pedersen EI, Markgraf CY, Segarra A, Hladik ML, Connon RE, Brander SM
Multigenerational, indirect exposure to pyrethroids demonstrates potential compensatory response and reduced toxicity at higher salinity in estuarine fish

2023
Mauduit F, Segarra A^, Sherman JR, Hladik ML, Wong L, Young TM, Lewis LS, Hung TC, Fangue NA, Connon RE.
Bifenthrin, a Ubiquitous Contaminant, Impairs the Development and Behavior of the Threatened Longfin Smelt during Early Life Stages.

2023
Hutton SJ, Siddiqui S, Pedersen EL, Markgraf CY, Segarra A, Hladik ML, Connon RE, Brander SM
Comparative behavioral ecotoxicology of Inland Silverside larvae exposed to pyrethroids across a salinity gradient

2022
Mauduit F, Segarra A, Mandic M, Todgham A, Baerwald M, Schreier AD, Fangue NA, Connon RE
Understanding risks and consequences of pathogen infections on the physiological performance1of outmigrating Chinook salmon.

2022
Gille DA, Barney BT, Segarra A, Baerwald MR, Schreier AD, Connon RE
Investigation of molecular pathogen screening assays for use in delta smelt

2021
Segarra A, Mauduit F, Amer NR, Biefel F, Hladik ML, Connon RE, Brander SM
Salinity Changes the Dynamics of Pyrethroid Toxicity in Terms of Behavioral Effects on Newly Hatched Delta Smelt Larvae

2021
Derby AP, Fuller NW, Huff Hartz KE, Segarra A, Connon RE, Brander SM, Lydy MJ
Trophic transfer, bioaccumulation and transcriptomic effects of permethrin in inland silversides, Menidia beryllina, under future climate scenarios.

2021
Leprêtre M, Faury N, Segarra A, Claverol S, Degremont L, Palos-Ladeiro M, Armengaud J, Renault T, Morga B
Comparative Proteomics of Ostreid Herpesvirus 1 and Pacific Oyster Interactions With Two Families Exhibiting Contrasted Susceptibility to Viral Infection.