Cecilia Giulivi
Professor
Professor
Molecular Biosciences
Molecular Biosciences
Research Profile
Education
1989, PhD, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
1985, MS, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
Active Research Grants
Co-Principal Investigator, Mitochondrial bioenergetics is associated with aggressive breast cancer growth, Jian-Jian Li (Principal Investigator), NIH
Co-Investigator, Genotype-phenotype relationships in fragile X families, Randi Hagerman (Principal Investigator), NIH
Co-Investigator, Fragile X-associated tremor/ataxia syndrome (FXTAS) pathology and anatomy: imaging and clinical correlates, Veronica Martinez-Cerdeno (Principal Investigator), NIH
Co-Investigator, Mitochondrial bioenergetics in persons with chronic kidney disease, Boback Roshanravan (Principal Investigator), NIH
Principal Investigator, The fragile X premutation and child development, (Principal Investigator), Emory University/NIH
Honors and Awards
1985-1987 Fellowship from National Research Council (CONICET) Buenos Aires, Argentina
1986 ICRO-IUB Fellowship, University Autónoma of Mexico, Mexico DF, Mexico
1986 Young Investigator Award, School of Pharmacy and Biochemistry, University of Buenos Aires
1988 Award Sandoz to the project Human ageing. Sandoz Laboratories, Switzerland
1989 Fellowship from Fundación Antorchas, Buenos Aires
1990 Award from Sociedad Argentina de Gerontologia y Geriatria to the research project Free radicals as a cause for ageing and atherosclerosis. Co-authors: Dr. A Boveris, Mosso, Vaccarezza
2010 Autism Science Top 10 Achievement for 2010
2011 National Institute for Environmental Health and Safety (NIEHS) as the author of one of the top 10 scientific papers of 2011. http://www.niehs.nih.gov/news/newsletter/2012/1/papers/index.htm
2012 National Institute for Environmental Health and Safety (NIEHS) paper of the month (9/2012; PMID: 3416855).
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416855/pdf/pone.0042504.pdf
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416855/pdf/pone.0042504.pdf
2016 Study featured on the cover of Biochemical Journal (Giulivi, C, Napoli, E, Tassone, F, Halmai, J, Hagerman, R. Plasma metabolic profile delineates roles for neurodegeneration, pro-inflammatory damage and mitochondrial dysfunction in the FMR1 premutation. Biochem J 473: 3871-88, 2016. 10.1042/BCJ20160585
Most Recent Five Book Chapters
2016 Wong S, Rose S,Giulivi C: Mitochondrial DNA damage in autism, Gulp R, Poderoso JJ, Boveris A, (ed), , . .
2003 Giulivi C, Oursler MJ: Role of mitochondrial oxygen and nitrogen reactive species in signaling. Chapter 17, Torres M, Fukuto J, Forman HJ, (ed), Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles, New York. 311-32.
1999 Giulivi C, Boveris A, Cadenas E: The steady-state concentrations of oxygen radicals in mitochondria, Gilbert DL, Colton CA, (ed), Reactive Oxygen Species in Biological Systems: Selected Topics, New York, NY. 77-102.
1994 Romero FJ, Ordoñez I, Giulivi C, Cadenas E: The interaction of sulfur compounds with ferrylmyoglobin, Packer L, Cadenas E, (ed), Biological Oxidants and Antioxidants, . 49-56.
1994 Cadenas E, Giulivi C, Ursini F, Boveris A: Electronically-excited state formation. Chapter 32, Tyson CA, Frazier JM, (ed), Methods of Toxicology, Vol. I, Part B: In Vitro Toxicity Indicators, . 384-99.
Research Focus
- Oxygen and nitrogen free radical biochemistry and chemistry in in vitro and in vivo model systems. Mechanistic aspects of oxygen and nitrogen free radical damage.- Mechanisms of mitochondrial dysfunction in neurological and metabolic diseases (fragile-X, tremor, ataxia syndrome, autism, Huntington's disease, type-2 diabetes).
Specialty Focus
Mechanisms of mitochondrial dysfunction in autism, fragile X tremor and ataxia syndrome, Huntington's disease, diabetes and nutrional imbalances as well as in malaria hosts.