Colin Reardon

Colin Reardon

Associate Professor

Anatomy, Physiology & Cell Biology


Education
2008, PhD, University of Calgary, Calgary, AB, Canada
2006, PhD, McMaster University, Hamilton, ON, Canada
2003, BS, McMaster University, Hamilton, ON, Canada
Active Research Grants
Co-Principal Investigator, Impacts of developmental exposure to perfluoroalkyl substances on the microbiota-gut-brain axis, Gareau, M (Principal Investigator), NIH NIEHS
Principal Investigator, Neuroimmune control of lung inflammation, (Principal Investigator), NIH/NIAID
Most Recent Five Book Chapters
2018 Gareau MG, Reardon C, Barrett KE, Sherman PM: Introduction: Probiotics and Psychopathology, Martin CR, Larkin D, (ed), Probiotics in Mental Health, . 29-41.
Research Focus
Neuroimmunology, host-pathogen interactions, Inflammatory Bowel Disease (IBD), Dendritic cells, Cytokine regulation of mucosal immunity, Regulatory T-cells.
Specialty Focus
The primary focus of my research has been on the mechanisms that control adaptive and innate immunity. Specifically we have on-going extramurally funded programs to (1) dissect the funcitonal neuronal circuitry that allows for control of immune cell activation systemically and in the lung, and (2) understand the contribution of neuro-immune interactions during bacterial infections.
Ten Recent Publications

2025
Murray K, Cremin M, Tay E, Schreiber S, Llyod E, Leigh W, Sanchez K, Ashfaq J, Reardon C^
Inhibition of acute lung inflammation by a neuroimmune circuit induced by vagal nerve stimulation.

2025
Cremin M, Ramirez VT, Sanchez K, Tay E, Murray K, Brust-Mascher I, Reardon C^
Substance P receptor signaling contributes to host maladaptive responses during enteric bacterial infection

2024
Populin LC, Rajala AZ, Matkowskyj KA, Saha S, Zeng W, Christian B, McVea A, Tay EX, Mueller EM, Malone ME, Brust-Mascher I, McMillan AB, Ludwig KA, Suminski AJ, Reardon C^, Furness JB
Characterization of idiopathic chronic diarrhea and associated intestinal inflammation and preliminary observations of effects of vagal nerve stimulation in a non-human primate

2024
Wu Y, Brust-Mascher I, Gareau MG, De Loera JA, Reardon C^
PrestoCell: A persistence-based clustering approach for rapid and robust segmentation of cellular morphology in three-dimensional data.

2023
Cremin M, Tay EXY, Ramirez VT, Murray K, Nichols RK, Brust-Mascher I, Reardon C^
TRPV1 controls innate immunity during Citrobacter rodentium enteric infection

2023
Cremin M, Schreiber S, Murray K, Tay EXY, Reardon C^
The diversity of neuroimmune circuits controlling lung inflammation

2021
Hennessey C, Keogh CE, Barboza M, Brust-Mascher I, Knotts TA, Sladek JA, Pusceddu MM, Stokes P, Rabasa G, Honeycutt M, Walsh O, Nichols R, Reardon C, Gareau MG
Neonatal enteropathogenic Escherichia coli infection disrupts microbiota-gut-brain axis signaling

2021
Murray K, Rude KM, Sladek J, Reardon C^
Divergence of neuroimmune circuits activated by afferent and efferent vagal nerve stimulation in the regulation of inflammation

2020
Ramirez VT, Sladek J, Godinez DR, Rude KM, Chicco P, Murray K, Brust-Mascher I, Gareau MG, Reardon C^
Sensory Nociceptive Neurons Contribute to Host Protection During Enteric Infection With Citrobacter rodentium

2020
Ramirez V, Swain S, Murray K, Reardon C^
Neural immune communication in the control of host-bacterial pathogen interactions in the gastrointestinal tract