Dori L Borjesson


Pathology, Microbiology & Immunology

4325 Vet Med 3A, Davis, CA 95616

Diplomate American College of Veterinary Pathology (Clinical Pathology)
1988, BA, The Colorado College, Colorado Springs, CO
1995, MPVM, University of California, Davis, CA
1995, DVM, University of California, Davis, CA
2002, PhD, University of California, Davis, CA
Active Research Grants
Co-Investigator, Xenogeneic Scaffolds for Heart Valve Tissue Engineering, Griffiths (Principal Investigator), NIH (NHBLI), RO1
Principal Investigator, Exploring the mechanisms by which feline mesenchymal stem cells downregulate T cell activation and proliferation, (Principal Investigator), Winn Feline Foundation
Principal Investigator, Deciphering feline stem cell interactions with CD8+ T cells, (Principal Investigator), VIRC Pilot Grant Program
Co-Investigator, Self assembling process in tissue engineering of articular cartilage, Athanasiou (Principal Investigator), NIH, RO1
Co-Principal Investigator, Stem Cell Tracking in the equine distal limb using Positron Emission Tomography, Spriet (Principal Investigator), UC Davis, Center for Equine Health
Principal Investigator, Mesenchymal stem cells for canine inflammatory brain disease, (Principal Investigator), Center for Companion Animal Health (CCAH) and Center for Equine Health (CEH)
Co-Principal Investigator, Mesenchymal Stem Cell Therapy for Gut Mucosal Recovery in the SIV Model of AIDS, Dandekar (Principal Investigator), NIH (NIAIS), R21
Honors and Awards
1988 Graduation with Distinction, The Colorado College
1991 Best research/presentation award for undergraduate thesis research
1994 Hanson-Welles Memorial Scholarship
1995 Phi Zeta Veterinary Honor Society
1997 ASVCP Excellence in Scientific Presentation Award
2001 CL Davis Student Scholarship Award
Most Recent Five Book Chapters
2014 Borjesson DL : Pancreas Cytology, Cowell RL, Tyler RD, Meinkoth JH, De Nicola, (ed), Diagnostic Cytology and Hematology of the Dog and Cat, 2nd Edition, St. Louis, MO. .
2014 Borjesson DL, DeJong KD : Cytologic examination of the urinary tract., Raskin RE, Meyer DJ, (ed), Canine and Feline Cytology, 3rd Edition, Philadelphia, PA. .
2011 Peroni J, and Borjesson DL : Anti-Inflammatory and Immuno-Modulatory Activities of Stem Cells, Stewart A, and Stewart M, (ed), Veterinary Clinics of North America: Equine Practice (Regenerative Medicine), Philadelphia. .
2011 Borjesson DL, Peroni JF : The regenerative medicine laboratory: facilitating stem cell therapy for equine disease, , Clin Lab Med, . 109-23.
2009 Borjesson DL, DeJong KD : Cytologic examination of the urinary tract, Raskin RE and Meyer DJ, (ed), Atlas of Canine and Feline Cytology, Philadelphia PA. .
Research Focus
I have been actively engaged in research on adult-derived mesenchymal stem cells (MSC). We have developed canine, feline and equine models to assess MSC safety and efficacy. My current research expertise is in MSC biology and immunomodulation. We have begun to define the mechanisms by which MSC alter the immune response and interact with cells of the immune system. Our most significant contribution is in the use of naturally occurring large animal models of disease to study cell therapy for inflammatory diseases. Specifically we are focused on naturally occurring inflammatory bowel disease in dogs, chronic gingivostomatitis in cats and spinal cord injury in dogs. With our canine work, we have focused on how MSCs interact with microbes important to GI health.
Specialty Focus
Clinical Pathology